Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior IT Audit Manager

$130k - $175k
Full-time

Repligen

This role will strengthen the company's control environment, reduce compliance and operational risk, and ensure timely execution of remediation efforts while enabling strategic technology investments to be implemented with appropriate governance. As the organization grows toward its long-term revenue objectives, this position provides critical capacity to support scalable, sustainable, and audit-ready IT operations.
  • Own and lead the ITGC and IT internal audit program, including planning, coordination, execution support, documentation quality, issue management, and executive-level status reporting.
  • Serve as a senior advisor to IT and business control owners on SOX ITGCs, automated controls, key reports, IT-dependent controls, governance expectations, and sustainable control design.
  • Collaborate with ITGC Manager to manage end-to-end audit lifecycle activities with external auditors and internal stakeholders, including walkthroughs, evidence readiness, testing coordination, deficiency evaluation, and timely issue resolution.
  • Lead the assessment of IT control risks across enterprise applications, infrastructure, cybersecurity, access management, change management, operations, and emerging technology initiatives.
  • Oversee remediation of IT-related audit findings and corrective actions, ensuring action plans address root cause, are appropriately documented, and are validated for operating effectiveness.
  • Partner with IT leadership, project teams, and process owners to embed control requirements into new system implementations, enhancements, SDLC activities, and process transformation initiatives.
  • Develop and maintain scalable IT compliance processes, templates, metrics, dashboards, and governance routines to improve program maturity, efficiency, consistency, and accountability.
  • Partner with ITGC Manager on continuous improvement efforts to reduce audit friction, strengthen evidence quality, improve control owner readiness, and enhance the overall IT risk and compliance operating model.
  • Manage internal corrective actions assigned to IT, coordinating with SME’s to identify and push forward remediation plans.
  • Provide coaching, direction, and quality review for team members, consultants, or control owners supporting ITGC, SOX, and internal audit activities.
  • Education and/or Work Experience Requirements:
    • Bachelor’s degree in Information Systems, Accounting, Finance, Computer Science, or a related field.
    • Minimum of 8 years of progressive experience in external audit, internal audit, IT compliance, IT risk management, or SOX advisory, with significant focus on IT General Controls and enterprise application controls.
    • Demonstrated experience leading audit programs, managing cross-functional stakeholders, and presenting risk and compliance matters to senior leaders.
    • Strong understanding of ITGC domains including access management, change management, computer operations, interface controls, automated controls, key reports, and SDLC governance.
    • Experience supporting enterprise environments such as SAP, Workday, ServiceNow, and related business applications preferred.
    • People leadership, indirect leadership, or consultant management experience preferred; ability to coach control owners and influence without authority required.
    • Excellent written and verbal communication skills, with the ability to translate complex IT risk and control topics into clear, actionable guidance for business and technology leaders.
    • Experience supporting environments such as SAP, Workday, ServiceNow preferred.
    Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated salary range for this role, based in the United States of America is $130,000-$175,000. Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.
Vacancy posted a month ago
Similar jobs that could be interesting for youBased on the Senior IT Audit Manager in Waltham, MA vacancy
  • $119k - $299.93k

     ...SummaryAt PwC, our people in audit and assurance focus on providing...  ...assessing governance and risk management processes and related controls...  ...operational processes. As a Senior Manager you will lead large projects...  ..., and controls, and leading IT-related controls assurance or... 
    Senior
    Full time
    H1b

    PwC

    Boston, MA
    3 days ago
  • $115k - $215k

     ...scientific findings and strategic recommendations to project teams, senior leadership, and external collaborators in a clear, concise, and...  ...organized, solutions-oriented scientist with the ability to manage multiple priorities simultaneously while driving innovation in targeted... 
    Senior

    Kymera Therapeutics

    Watertown, MA
    3 days ago
  • $154.4k - $242.55k

     ...true to the best of my knowledge.Job DescriptionJoin Takeda as a Senior/Principal Scientist, Cell Based-Potency Assay Development. As...  ...Operating with considerable autonomy, you serve as a consultant to management and an external spokesperson on major matters, often working... 
    Senior
    Minimum wage
    Contract work
    Temporary work
    Local area

    Takeda

    Lexington, MA
    3 days ago
  • $154.4k - $242.55k

     ...application is true to the best of my knowledge.Job DescriptionJoin Takeda as a The Senior/Principal Scientist, Analytical Cell Line Engineering and Bioessay Development plays a key role in managing and performing scientific research, development, and testing of new products,... 
    Senior
    Minimum wage
    Temporary work
    Local area
    Shift work

    Takeda

    Lexington, MA
    3 days ago
  • $86.8k - $165.2k

     ...cybersecurity team is seeking a Senior Information Systems Security...  ...Information Systems Security Manager (ISSM) to ensure adherence with...  ...monitoring system compliance, auditing, security plan development and...  ...Customers, Information Technology (IT).Familiarity with large multi-... 
    Senior
    Temporary work
    Work experience placement
    Work at office
    Remote work
    Relocation package
    Flexible hours

    Raytheon

    Boston, MA
    20 hours ago
  •  ...clinical staff. Acts as a mentor to less experienced staff. Participates in operational duties assigned by and under the direction of the manager. Key Responsibilities Examinations/Procedures Performs the more complex imaging examinations while providing a safe... 
    Senior
    Flexible hours

    Boston Children's Hospital

    Waltham, MA
    20 hours ago
  • We're committed to bringing passion and customer focus to the business.SummaryLocation: New York, NY; Waltham, MA - Headquarters; East Norriton, PA; Princeton, NJType: Full time
    Senior
    Full time

    Trinity Life Sciences

    Waltham, MA
    4 days ago
  • Reference: 628547Posted: 2026-07-27Location: Boston, MassachusettsCompany: Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody discovery efforts...
    Senior

    Planet Pharma

    Boston, MA
    1 day ago
  •  ...Job Description Job Description Senior Principal Salesforce Business Systems Manager We are currently engaged in an executive search for a Senior Principal Salesforce Business Systems Manager. This role is with an international company who is a leader in their field... 
    Senior

    New Directions, IT & Digital Talent Solutions

    Waltham, MA
    more than 2 months ago
  • $120k - $160k

     ...the company and you can be part of that team. Job Summary The QC Senior/Principal Scientist for Analytical Method Validation is a key...  ...collaborative environment, working with minimal direction and able to manage workload based on changing priorities. Works independently and... 
    Senior
    Immediate start
    Visa sponsorship

    Genezenlabs

    Lexington, MA
    1 day ago
  • $95.7k - $126.7k

     ...vulnerabilities identified during risk assessments, audits, inspections, etc.Promote awareness of security issues among management and ensure sound security principles are...  ...remediation.Lead and align information technology (IT) security priorities with the security strategy... 
    Casual work
    Remote work
    Flexible hours

    Lincoln Laboratory

    Lexington, MA
    2 days ago
  • $177k - $336k

    A leading pharmaceutical company in Waltham, MA is seeking an Associate General Counsel, Transactions, to advise on mergers, acquisitions, and pharmaceutical licensing. This role requires 15+ years of experience and a J.D. degree, focusing on complex transactions and providing...
    Senior

    BioSpace, Inc.

    Waltham, MA
    4 days ago
  •  ...deliver unified access and security management programs that eliminate...  ...leadership, product, engineering, IT, legal, and compliance teams...  ...with legal, compliance, and audit teams to ensure adherence to regulatory...  ..., with at least 5+ years in a senior leadership role. Proven... 
    Work at office
    Local area

    Imprivata

    Waltham, MA
    20 hours ago
  • $75k - $95k

    Job Title Location 7 Wells Ave Suite 11, Newton, MA, 02459, United States Base Pay $75,000.00 - $95,000.00 / Year Employee Type FT Exempt Contact Information Name Ryan Galvin Phone 000-000-000 Email ****@*****.*** Description
    Senior

    Barkan

    Newton Center, MA
    4 days ago
  •  ...The MITRE Corporation in Bedford, Massachusetts, is seeking a Solution Lead Senior Principal (SLSP) to oversee 1-3 projects, driving them through the MITRE Innovation Lifecycle. The role requires strong project leadership and an entrepreneurial mindset to achieve disruptive... 
    Senior

    MITRE

    Bedford, MA
    11 hours ago
  • Position: Senior Scientist (solid state) Location: Waltham, MAJob Id: 650 # of Openings: 1 Position: Senior ScientistReports To: Solid State Team ManagerLocation: Waltham, MassachusettsA123 Systems, LLC... 
    Senior

    A123 Systems

    Waltham, MA
    20 hours ago
  • $120k - $160k

     ...problem they take on.$120,000 - $160,000 a yearTutor offers competitive benefits including fully employer-covered health insurance, a managed 401(k), and regular in-office meals. We host social events and maintain a collaborative, low-ego work culture where people are... 
    Senior
    Full time
    Work at office
    Shift work

    Tutor Intelligence

    Watertown, MA
    2 days ago
  • Trinity Partners in Waltham, MA, is seeking an experienced Associate Director for Account-Based Marketing to design and execute strategies aimed at pharmaceutical and biotech accounts. The role involves collaborating closely with Sales and Marketing to drive growth and...
    Senior

    Trinity Partners

    Waltham, MA
    4 days ago
  •  ...Senior Director, Principal Gifts About the Company Philanthropic organization supporting Indigenous culture & individuals Industry Non-Profit Organization Management Type Non Profit Founded 2017 Employees 11-50 Categories... 
    Senior

    Confidential

    Boston, MA
    1 day ago
  • $110k - $135k

     ...in Waltham, Massachusetts is looking for an Executive Assistant to support senior leadership in a dynamic biotech environment. This position will provide high-level administrative support, manage complex calendars, and coordinate travel arrangements. The ideal candidate... 
    Senior

    Korsana Biosciences

    Waltham, MA
    4 days ago
  • $52.2k - $101.79k

     ...looking for a candidate who will provide senior level support for government regulatory contracts...  .... The role involves developing and managing contracts for healthcare services to...  ...regulatory requirements, and conducting audits of operational implementations. A minimum... 
    Senior

    Molina Healthcare

    Waltham, MA
    2 days ago
  •  ...Torch Technologies, a 100% employee-owned company, seeks a Senior Systems Engineer to support the AFLCMC/ESG at Hanscom AFB, MA. You...  ...development, integration, and fielding. The role emphasizes risk management, formal reviews, and IPT collaboration; U.S. Citizenship is... 
    Senior

    PVH (Tommy Hilfiger/Calvin Klein)

    Lincoln, MA
    20 hours ago
  • A renewable energy company based in Weston, Massachusetts, seeks a Senior Analyst - Operations and FP&A. The successful candidate will drive financial planning and operational analytics, collaborate with senior leadership and external stakeholders, and prepare analytical... 
    Senior
    Full time

    Vanguard Renewables Ag

    Weston, MA
    4 days ago
  •  ...Changemaker Helping people by developing novel product candidates is more than just meeting a need or conducting a business transaction. It's more than science for science's sake. Improving human health changes the world. At Keros, we're making progress every day toward a... 
    Senior

    Keros Therapeutics

    Lexington, MA
    2 days ago
  •  ...manufacturing company just outside of Boston is seeking a Staff or Senior Accountant to join their team. This role will focus on the GL,...  .... Responsibilities Include Support the month-end close process Manage cost and inventory accounting Partner with various other divisions... 
    Senior

    KBW Financial Staffing & Recruiting

    Newton, MA
    3 days ago
  • MIT Lincoln Laboratory's Air Traffic Control & Weather Systems Group in Lexington, MA seeks a meteorologist with radar analysis and algorithm development expertise to contribute to national infrastructure needs. The role focuses on wind-based hazardous weather for aviation...
    Senior

    MIT Lincoln Laboratory

    Lexington, MA
    3 days ago
  •  ...experience in tools like O9 Solutions and Oracle ASCP. The ideal candidate will collaborate cross-functionally to ensure data integrity and foster process improvements across various teams, playing a critical role in managing business functionalities. #J-18808-Ljbffr... 
    Senior

    Helen of Troy

    Arlington, MA
    4 days ago
  •  ...HX5, LLC is seeking a Senior Logistics Manager to support the HNJ Division at Hanscom Air Force Base, MA. The role emphasizes independent work,...  ...and guidance. Qualified candidates will have DoD experience, IT logistics background, and strong MS Office skills. Travel and... 
    Senior

    HX5

    Lincoln, MA
    4 days ago
  •  ...seeking a technical expert to empower enterprises with innovative storage solutions. This role involves leading presales evaluations, managing customer onboarding, and providing troubleshooting support for enterprise storage tools. The ideal candidate has at least 5 years... 
    Senior

    INFINIDAT

    Waltham, MA
    4 days ago
  •  ...curious and driven to learn new things by answering challenging business questions. Position Responsibilities: Coordinating with and managing data collection vendors Responding to clients' needs Creating client reports in PowerPoint Using MarketSight / SPSS to manage and... 
    Senior

    PLP Group

    Waltham, MA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior IT Audit Manager. Be the first to apply!