Senior Organic Chemist
$110k - $170kAdiabatic Materials
Adiabatic Materials | Somerville, MA
Reinvent chemistry. Decarbonize industry. Electrify the future.
Today, most chemicals are still made using heat from burning fossil fuels in energy-intensive, polluting processes. Adiabatic Materials has developed a fundamentally new approach: an electrochemical synthesis platform that uses clean electricity instead of heat. The platform grew out of 15 years of Harvard research and has been demonstrated for a broad range of chemicals. Adiabatic recently spun out of Harvard and is scaling its operations in the Boston area.
Why Adiabatic might be great for you
We're a small, early-stage team working on hard, meaningful problems. If you get energy from making things actually work and want your contributions to directly shape a company's trajectory, this could be a great fit.
- You'll be our first full-time synthetic organic chemist hire. You'll own the chemistry around and beyond the electrochemical step, from route design to characterized, written-up results, working directly with our Chief Scientific Officer and the founders.
- Apply your synthetic expertise to a new platform. You'll develop new reactions, establish new routes to key targets, and validate where our chemistry can outperform conventional approaches.
- Real ownership. As one of our early employees you'll have more influence on direction than you would at a big company: you'll help choose the problems we pursue, shape how we solve them, and influence how the R&D team grows, working with our Chief Scientific Officer, who is setting the overall research direction.
- Chemistry that is genuinely new. Electrochemical routes to pharmaceutical and fine chemical targets, with room to develop new reaction types.
- Equity and upside. You'll share in the value you help create, alongside a mission-driven team that cares about science and sustainability.
The Role
We have built a novel and differentiated chemistry platform, and see many opportunities beyond what we have already explored. Your job will be to expand its capabilities and demonstrate its value on real pharmaceutical and fine chemical targets.
Working closely with our Chief Scientific Officer, you'll identify and validate new reaction classes, devise routes that take advantage of our chemistry, and turn those ideas into robust experimental results. You'll own the synthesis end-to-end: designing and running reactions, developing and optimizing new transformations, and rapidly purifying, characterizing, and reporting products.
Electrochemistry experience is not required. We can get an excellent synthetic chemist up to speed on our system quickly. What matters most is strong synthetic intuition, speed at the bench, and the ability to take a target from route concept through validated chemistry.
What You'll Do
Synthetic Route Execution: Take high-level direction, then develop and run whole routes independently: read the procedure, execute it correctly, adapt it where it doesn't transfer, and deliver assigned targets.
Reaction Development: Develop and optimize conditions for reaction types beyond our current set, including those requiring standard air-free technique.
Electrochemical Steps: Learn the cell and mediator chemistry hands-on with our Director of Electrochemical Engineering, run the electrochemical step as one step among multiple, and help expand the reaction scope.
Purification and Characterization: Purify and characterize independently and quickly, and set a documentation and reporting standard the growing R&D team can follow.
Safety and Lab Standards: Work within the Greentown Labs safety environment from day one and run hazard assessments for every new reaction type you introduce.
Team and Technical Collaboration: Contribute in R&D meetings, work with our scientific advisors on open chemistry questions, and mentor our chemistry co-op informally on technique.
What We're Looking For
Many strong candidates don't fit a standard blueprint. If you bring relevant experience and are excited about what we're building, we encourage you to apply even if you don't check every box.
Required:
- PhD in chemistry or a closely related field with a research focus in organic synthesis: new reactions, condition optimization, novel compounds
- Deep and diverse hands-on experience across many reaction types
- Standard air-free technique on a Schlenk line, in vials and flasks
- Independent purification by column chromatography and characterization by NMR, IR, MS, UV-Vis, HPLC and GC (some hands-on, some via analytical labs)
Nice to Have:
- 2-4 years of industry or startup experience is a plus, but not a hard requirement: if you're coming straight out of a PhD, or have internship experience only, we'd still like to hear from you
- Retrosynthetic analysis
- Cheminformatics or computational chemistry
- Electrochemistry experience is not required. We already have expertise in this area in our team and expect you to learn it on the job within weeks
Working Style & Character:
- You are a team player who joins meetings and contributes, and who cares about building a great team culture as we grow
- You are good at taking high-level direction and running with it
- You have good judgement about when to ask for help: you don't ask permission for everything, but you also don't spend two days stuck on a five-minute question
- You are good at managing your own time against milestones and deadlines
- You operate safely without being reminded
Logistics
- Location: In-person at Greentown Labs, Somerville, MA
- Work style: Flexible, family-friendly schedule
- Compensation: $110K to $170K/year, plus meaningful equity and benefits (negotiable). The range is deliberately broad because it spans a fresh PhD through to five or more years of industry experience
How to Apply
Please submit your resume and include a few sentences about why you're excited about Adiabatic and how this role aligns with your experience. This is also an opportunity to highlight experiences that you feel are particularly relevant for the role. This doesn't need to be a formal cover letter; we just want to understand what motivates you.
The pay range for this role is:
110,000 - 170,000 USD per year (Somerville, MA)
- Sail Biomedicines is seeking a Senior Research Associate to join the Targeted Drug Delivery team. This onsite, lab-based role supports the development of targeted lipid nanoparticle formulations for nucleic acid delivery. The role requires hands-on experiments, collaboration...Senior
$66.8k - $124k
Job Description Lab-based role carrying out multi-step organic chemistry synthesis routes to prepare organic molecules testing molecular biology hypotheses and disease-related pathways. Use mechanistic organic chemistry to perform functional group transformations and build...Suggested- Lindonlight seeks a Senior Scientist, Biochemistry to lead biochemistry strategy, develop assays, and drive HTS campaigns for pediatric brain tumor targets. You will work with CROs, optimize assay robustness, and contribute to lead progression with kinase-focused assays...Senior
$170k - $215k
...visit us on LinkedIn. Position Summary: Reporting to the Senior Director of Process Development and MSAT, the Associate... ...readiness. This role sits within Aura’s Technical Operations organization, supporting dye/API process development from initial route design...SuggestedTemporary work- Johnson & Johnson Innovative Medicine in Cambridge, MA / Spring House, PA seeks a Distinguished Scientist, Nonclinical Safety Leader to guide toxicology strategies across discovery and development. You will lead cross-functional teams, nominate candidate molecules, and ...Senior
- Regeneron is seeking a Senior Toxicologist to lead nonclinical development programs with regulatory oversight and cross‑functional collaboration. The role requires deep GLP and regulatory expertise to design, conduct, and report studies in rodent and non‑rodent models...Senior
- ...Vice President for Principal & Major Gifts to lead strategy, staffing, and fundraising for the PMG program. You will partner with senior leaders to advance Institute priorities and oversee a team driving major gifts across multiple disease areas. The role requires a decade...Senior
- Regeneron Pharmaceuticals, Inc (USA) is seeking a Senior Toxicologist to lead nonclinical development programs with guidance from their supervisor, collaborating within cross-functional project teams. The role requires deep knowledge of GLP regulations and FDA/ICH safety...Senior
- Senior Toxicologist The Senior Toxicologist utilizes their scientific expertise and regulatory experience to lead nonclinical development... ...and safety pharmacology studies at contract research organizations. Communicate toxicology study findings, including relevant interpretation...SeniorContract work
- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...Senior
$220k - $270k
Zealand Pharma U.S., Inc. in Cambridge is seeking a Principal or Senior Principal Scientist for Peptide & Bioconjugate Drug Discovery. This role involves leading the development of peptide drug discovery capabilities, with significant responsibilities for strategy and...Senior$128.6k - $210k
The Senior Toxicologist utilizes their scientific expertise and regulatory experience to lead nonclinical development programs with... ...toxicology and safety pharmacology studies at contract research organizations. Communicate toxicology study findings, including relevant...SeniorContract work- Lila Sciences in Cambridge, MA is looking for a Senior/Principal Scientist specializing in Small Molecule Therapeutics. This role focuses on leading hit identification through DNA-encoded libraries (DEL) and executing robust screening methodologies in collaboration with...Senior
- Sanofi is seeking a Senior Principal Scientist in Cambridge, MA to lead preclinical immunology programs and shape translational strategies that inform clinical development and lifecycle management. You will drive collaborations with Development, Medical Affairs, and Commercial...Senior
$148k - $208k
...safety team at Lila that will engage all core teams within the organization (science, model training, lab integration, etc.), to identify... ...of superintelligent scientific systems. We are seeking a chemist to map risk across the chemical sciences domain: you will connect...SeniorFull timeWork at officeLocal areaFlexible hours- Forrester Research, Inc. is seeking a Principal Analyst to lead the Enterprise Solutions Architecture Practice within the Technology Architecture & Delivery Research Group. The role guides CIOs, CTOs and IT leaders, driving insights across architecture, platforms, governance...Senior
- Harvard University Central Administration (CADM) seeks a Senior Director of Principal Gifts to lead a portfolio of high-capacity donors and prospects, with the potential to secure 8- and 9-figure gifts. The role partners with university leaders and fundraisers across Harvard...SeniorWork at office
- Sanofi Cambridge is seeking a Senior Principal Scientist to lead preclinical translational efforts within the Type 2 Immunology cluster. You will shape translational strategies that inform clinical development and lifecycle management, collaborating across Development,...Senior
- Alsym Energy seeks a Computational Physical Chemist to shape electrolyte discovery and development. You will blend physical chemistry with ML/AI, using MD or DFT to propose formulations and transfer insights into battery performance, lifetime, and safety. Join the Discovery...Senior
- ...We are seeking a passionate PhD-level synthetic chemist to drive the discovery of small molecules for next-generation 3D printing resins... ...position involves rapid exploration of chemical space through organic synthesis to develop photochemical and photophysical structure-...
- ...study designs and data interrogation deliver high-value results Present findings to interdisciplinary teams spanning biologists, chemists, clinicians, and machine learning scientists Requirements ~ Ph.D. or equivalent in biology, computational biology, or related...Senior
- ...Kymera Therapeutics seeks a Senior or Principal Scientist in Targeted Proteomics to lead mass spectrometry-based assay development and execution supporting targeted protein degradation research programs. The role combines scientific strategy, experimental design, and...Senior
- Judge Group, Inc. is seeking a Senior Principal GMP Compliance Auditor to lead independent GMP audits across pharmaceutical sites, laboratories, suppliers, CMOs, and quality systems. This role focuses on regulatory compliance, inspection readiness, and quality-system effectiveness...SeniorRemote job
$138.6k - $257.4k
...mechanism of action studies to accelerate the development of transformative therapies for patients.Job DescriptionInternal Job Title: Senior Principal Scientist/Associate DirectorPosition Location: Cambridge, MA, onsite #LI-onsiteJob Description:We are seeking an...SeniorFull time$115k - $215k
...scientific findings and strategic recommendations to project teams, senior leadership, and external collaborators in a clear, concise, and... ....Domain leadership with cross-functional drug discovery:Highly organized, solutions-oriented scientist with the ability to manage...Senior- Mariana Oncology is seeking an experienced Radiochemist to advance personalized medicine and radiopharmaceuticals in a lab-based setting. You will develop radiolabeling methods, support in vitro and in vivo studies, and contribute to pharmacokinetic work while presenting...Senior
- ...Basic knowledge of statistics and experimental design Excellent organization, communication, and presentation skills High level of... ...confidential according to EEO guidelines.SummaryType: ContractFunction: ResearchExperience level: Mid-Senior LevelIndustry: PharmaceuticalsImmediate start
$119.7k - $222.3k
...acceleration of PKS/clinical pharmacology deliverables across the organization. Our unique organizational structure enables colleagues to... ...Principal Scientist II. 4+ years of experience to be considered for Senior Principal Scientist.Extensive and in-depth knowledge of...SeniorFull time$138.6k - $257.4k
...reproducible, and well-documented analytical processes that improve operational resilience and cross-site consistencyImprove image data organization, sharing, and best practices to support collaboration with Oncology Data Science, Data42, and enterprise AI initiativesAI/ML-...SeniorFull time$148.5k - $214.5k
Job title: Senior Principal Scientist Type 2 ImmunologyLocation:Cambridge, MAAbout the JobImmunology and Inflammation Therapeutic AreaWe... ...relationships effectively across a matrixed global organization. Communicate research findings clearly and compellingly to diverse...SeniorFull time
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Organic Chemist. Be the first to apply!
- senior business development Somerville, MA
- senior research specialist Somerville, MA
- american senior communities Somerville, MA
- senior devops engineer remote Somerville, MA
- senior information technology project manager Somerville, MA
- senior vmware engineer Somerville, MA
- sr marketing manager Somerville, MA
- senior dynamics crm developer Somerville, MA
- senior development executive Somerville, MA
- senior analytical scientist Somerville, MA



