Scientist, Oncology Bioinformatics

Overview The role will support Moderna’s oncology pipeline by contributing computational analyses across research and preclinical development. You will work at the intersection of antigen discovery, tumor immunology, and multi-omics data analysis, applying established and emerging computational approaches to help characterize tumor biology and immune responses. In this highly collaborative environment, you will partner closely with oncologists, immunologists, biologists, and platform technology teams to generate insights that inform target discovery and early-stage therapeutic development for mRNA-based cancer vaccines and immunotherapies. Here’s What You’ll Do Analyze and integrate multi-omics datasets (e.g., WES/WGS, RNA-seq, single-cell) to characterize tumor antigen landscapes Apply computational methods to support antigen discovery efforts and investigate tumor-immune interactions and underlying mechanisms Leverage internal and public datasets (e.g., TCGA, GTEx, IEDB) for biomarker exploration and hypothesis generation Develop and maintain reproducible analysis workflows using Python, R, and cloud-based infrastructure (e.g., AWS) Collaborate with cross-functional teams in immunology, oncology, and translational research to support experimental design and data interpretation Communicate results clearly through presentations, summaries, and documentation to support team decision-making Basic Qualifications Ph.D., or M.S. with 4+ years of experience, in Bioinformatics, Computational Biology, or a related field Experience with high-throughput sequencing data analysis, including DNA-seq and RNA-seq Proficiency in Python and/or R for data analysis Experience working in cloud environments (e.g., AWS) Demonstrated ability to apply computational approaches to biological or early-stage translational research problems This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work Preferred Qualifications Exposure to immuno-oncology, cancer vaccines, tumor immunology, or computational immunology Familiarity with neoantigen prediction approaches, including HLA typing and peptide-MHC binding tools (e.g., NetMHCpan) Experience with immunogenomics resources (e.g., IEDB, TCGA) Strong collaboration and communication skills in a team-oriented environment Pay & Benefits At Moderna, we believe that when you feel your best, you can do your best work. That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between. Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs A holistic approach to well-being, with access to fitness, mindfulness, and mental health support Family planning benefits, including fertility, adoption, and surrogacy support Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Savings and investment opportunities to help you plan for the future Location-specific perks and extras The salary range for this role is $121,600.00 - $194,500.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance. About Moderna Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Our Working Model As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal Opportunities Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person\'s race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at View email address on click.appcast.io. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #J-18808-Ljbffr