Sr Scientist, Structural Chemistry (United States - California - Foster City)
$169.32k - $219.12kGilead Sciences Inc.
This job is with Gilead Sciences Inc., an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.
At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job DescriptionKey Responsibilities
- Apply cryo-EM and/or X-ray crystallography to determine high-resolution structures of proteins and macromolecular complexes relevant to drug discovery
- Conduct cryo-EM workflows including grid preparation, data collection, image processing, 3D reconstruction, and model building
- Collaborate closely with cross-functional teams to integrate structural insights into medicinal chemistry and biologics design efforts including hit validation and hit-to-lead optimization.
- Contribute to the operation, optimization, and maintenance of cryo-EM instrumentation and workflows
- Present results clearly to internal project teams and contribute to scientific publications and reports
- Independently manage multiple projects in a fast-paced environment and deliver impactful results
Basic Qualifications
- PhD in Structural Biology or related field with postdoctoral training in solving atomic resolution structures of macromolecular complexes
- Minimum of 3 years of relevant experience in structural biology, preferably including biopharmaceutical industry experience
Preferred Qualifications
- Extensive experience in single-particle cryo-EM, including grid preparation, optimization, data acquisition, processing, 3D reconstruction, and model building
- Hands-on experience in recombinant protein construct design, expression, purification, and characterization
- Excellent communication, collaboration, and interpersonal skills in a matrixed team environment
- Strong organizational skills with the ability to manage multiple projects independently
For additional benefits information, visit:
* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
For jobs in the United States:
Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex , age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact View email address on apply.placed-app.com for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Gilead Employees and Contractors:
Please apply via the Internal Career Opportunities portal in Workday.
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