HR Generalist

HR Generalist

Responsibilities

Employee Relations & HR Support

• Serve as a trusted point of contact for employees and managers regarding HR-related questions, including compensation, benefits, PTO, policies, and procedures
• Investigate employee relations issues and workplace complaints, recommend corrective actions, and partner with the Legal department and HR leadership as appropriate.
• Handle confidential and sensitive employee information with professionalism, discretion, and strict adherence to company privacy and confidentiality standards.
• Work closely with managers and employees to strengthen working relationships, enhance engagement, and support employee retention initiatives.

HR Operations & Compliance

• Maintain accurate and timely employee data by processing and documenting personnel actions such as new hires, promotions, transfers, job changes, and terminations.
• Ensure data integrity across HR systems to support payroll, benefits administration, compliance, and reporting requirements.
• Apply working knowledge of employment laws and regulations, including FMLA, ADA, leaves of absence, return-to-work programs, and NLRA; escalate and partner with Legal or HR leadership as needed.
• Support audits and ensure compliance with internal policies and external regulatory requirements.

Talent & Employee Lifecycle Support

• Assist with new hire onboarding and orientation, including coordination of paperwork, scheduling, and delivery of orientation content.
• Support performance management processes, recognition programs, training initiatives, and company-wide HR events.
• Assist with benefits administration activities, including open enrollment support, employee education, and issue resolution.

Collaboration & Continuous Improvement

• Partner with HR leadership, including the SVP, HR, to support the execution of People initiatives aligned with business objectives.
• Act as a liaison with other HR functions to ensure consistent and effective service delivery.
• Contribute to HR projects, data analysis, reporting, and process improvements to enhance employee experience and operational efficiency.

Required Skills & Competencies

• Must have biotech experience and be willing to be onsite 4 days a week
• Working knowledge of compensation practices and benefits administration with the ability to identify issues and apply established programs.
• Strong analytical and problem-solving skills, including basic data analysis and interpretation.
• Excellent verbal and written communication skills with strong organizational, documentation, and follow-up abilities.
• High level of discretion and professionalism when handling confidential and sensitive employee matters.
• Proficiency in Microsoft Office applications (Outlook, Word, Excel) and HRIS platforms.
• Ability to manage multiple priorities, meet deadlines, and adapt to changing business needs.
• Self-motivated, proactive, and collaborative team player.
• Ability to interact effectively and professionally with employees at all levels, including management, vendors, and external partners.

Qualifications

• Bachelor's degree in Human Resources, Business Administration, or a related field, or equivalent professional experience.
• Minimum of 5-7 years of progressive HR experience, preferably in an HR Generalist or similar role.
• Hands-on experience supporting employee relations, HR operations, and compliance.
• Familiarity with HR systems, reporting tools, and standard HR processes.
• Demonstrated ability to resolve employee issues using sound judgment and practical HR solutions.
• Strong organizational skills with attention to detail and accuracy.

The base pay range for this position at commencement of employment is expected to be between $145K and $160K / year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.

Protagonist Therapeutics is a discovery through late-stage development biopharmaceutical company. The Company's proprietary peptide technology platform enables de novo discovery of peptide therapeutics. Two novel peptides derived from Protagonist's proprietary discovery platform are at or near commercialization. ICOTYDE™ (icotrokinra) is approved in the U.S. for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age and older who weigh at least 40 kg who are candidates for systemic therapy or phototherapy. ICOTYDE is the first and only targeted oral peptide that precisely blocks the Interleukin-23 receptor (IL-23R) licensed to Janssen Biotech, Inc.,a Johnson & Johnson company. ICOTYDE was jointly discovered by Protagonist and Johnson & Johnson scientists, with Protagonist having primary responsibility for the development of ICOTYDE through Phase 1, and Johnson & Johnson assuming responsibility for further development and commercialization. An NDA for rusfertide, a first-in-class hepcidin mimetic peptide that is being co-developed with Takeda Pharmaceuticals pursuant to a worldwide license and collaboration agreement entered in 2024, is under priority review with the FDA. Protagonist holds an option to co-commercialize rusfertide in the U.S. through a 50/50 profit and loss share structure or can opt-out of this structure. The Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs.

More information on Protagonist, its pipeline drug candidates, and clinical studies can be found on the Company's website at