Principal Scientist - Multiscale Separations Team Lead
Merck
Merck seeks a Principal Scientist to lead its Separations Sciences team in Rahway, New Jersey. The role combines scientific expertise in purification and analytical chromatography with laboratory leadership, capability development, and mentorship across multiple drug modalities.
Responsibilities
- Serve as subject matter expert providing scientific leadership for purification and analytical activities supporting drug development pipeline
- Provide technical guidance on chromatographic purification, analytical separations, and impurity isolation while resolving complex scientific challenges
- Partner with digital technologies team to implement innovative technologies, automation workflows, and laboratory informatics platforms
- Mentor and develop scientists and laboratory staff, building technical expertise and leadership capability across the organization
- Collaborate with process chemistry, pharmaceutical sciences, and automation teams to support project progression and capability advancement
Requirements
- Ph.D. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or related field with 8+ years pharmaceutical/biotech experience
- M.S. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or related field with 10-12 years pharmaceutical/biotech experience
- Extensive hands-on expertise in HPLC, uHPLC, LCMS, SFC, and preparative chromatography technologies
- Demonstrated experience delivering purification solutions across multiple scales from micrograms to kilograms
- Experience supporting multiple therapeutic modalities including small molecules, peptides, and adjuvants
- Working knowledge of orthogonal detection technologies such as PDA and charged aerosol detection
- Ability to provide scientific leadership and influence technical direction within laboratory environments
Vacancy posted 6 days ago
Similar jobs that could be interesting for youBased on the Principal Scientist - Multiscale Separations Team Lead in Rahway, NJ vacancy
$156.9k - $247k
Job DescriptionWe are seeking a Principal Scientist to join our Separations Sciences team, within the Analytical Enabling Capabilities Organization, located in Rahway, New Jersey.The successful candidate will provide scientific leadership and operational oversight for purification...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ4 days ago- Merck & Co., Inc. in Rahway, NJ, seeks a Principal Scientist to lead purification and analytical... ...leadership with hands-on execution to advance Separation Sciences capabilities. The successful... ...improvements while mentoring teams and collaborating across Process Chemistry...Suggested
- Scorpion Therapeutics in Rahway, NJ seeks a Principal Scientist to lead Separation Sciences within Analytical Enabling Capabilities, supporting drug development across modalities including small molecules, biologics, peptides, and ADCs. You will drive chromatography and...Suggested
$142.4k - $224.1k
...&D) is seeking an Associate Principal Scientist position at the Rahway, New... ...fast-paced, multidisciplinary team environment. The qualified... ...research and publish. Experience leading small groups of technical... ...:Hands-on experience in separation sciences with chromatography...PrincipalFull timeFor contractorsLocal areaMerck Sharp & Dohme (MSD)
Rahway, NJ3 days ago$142.4k - $224.1k
...Merck seeks an Associate Principal Scientist to lead analytical method development for biologics in the Rahway, New Jersey laboratory. The role... ...+ years; or Ph.D. with 3+ years Hands-on expertise in separation sciences including chromatography techniques (SEC, RP,...PrincipalMerck
Rahway, NJ5 days ago$282.2k
...mutual respect, encouragement and teamwork. As part of our global team, you'll have the opportunity to collaborate with talented and... ...and expanding your career. The Senior Director (Sr. Principal Scientist) has primary responsibility for the planning and directing clinical...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ4 days ago$190.8k - $300.3k
...Preclinical Leaders, Compound Leaders, and scientists across NDS and/or Preclinical Development... ...industry collaborations, and proactively lead internal cross-departmental initiatives... ...related field, with pharmaceutical program team experience and demonstrated expertise in...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ10 hours ago$173.2k - $272.6k
...seeking an accomplished and highly motivated Principal Scientist to provide strategic and scientific... ...Neuroscience portfolio. This role will lead the design, execution, analysis, and... ...partnership with cross-functional development teams.Translate disease biology and...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ2 days ago- ...Role Associate Principal Scientist supporting biologics sterile product development within the Sterile Product Development (SPD) group. Objectives Lead innovative biologics formulation and process development, support early and late-stage candidates, and contribute...Principal
Scorpion Therapeutics
Rahway, NJ1 day ago $173.2k - $272.6k
...a highly motivated and collaborative scientist/engineer to join our team. This is a unique opportunity to play... ...development to commercialization while leading highly visible technical initiatives across our global network.The Principal Scientist, Engineering position...PrincipalFull timeContract workFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ2 days ago$255.8k - $402.7k
...exciting opportunity for a physician-scientist to join our group as a Principal Scientist (Clinical Director) in... ...therapeutic areas as part of a global team. Primary responsibilities for the Principal... ...development strategyTaking a lead role in developing and executing clinical...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ2 hours ago$173.2k - $272.6k
Job DescriptionPrincipal Scientist Job Description: Our company's Pharmaceutical Sciences and Clinical Supply (PSCS) organization... .... In this role, the individual will be responsible for leading CMC project teams and the formulation development of new chemical entities...PrincipalFull timeFor contractorsLocal areaVisa sponsorshipFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ2 days ago$156.9k - $247k
Job DescriptionThe Human Factors team plays a pivotal role in combination product... ...management. This person will lead several Human Factors scientists to perform and manage human factors... ...Responsibilities and Activities:The Principal Scientist is responsible for managing...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ4 days ago- # Associate Principal Scientist, Preclinical DevelopmentRahway, New Jersey, United States of America... ...to commercialization. Our development teams ensure robust composition, primary... ...Product Development.**Primary duties:**Lead/ contribute towards the new, innovative...Principal
Biopharma Careers
Rahway, NJ2 days ago $145.48k - $224.1k
...clinical endpoint data (efficacy and safety) and pharmacokinetic data (raw concentration data and derived PK parameters);Experence leading study programming deliverables for multiple studies.Requires 1 year of experience with at least one software other than SAS (e.g.,...PrincipalFull timeFor contractorsSecond jobLocal areaMerck Sharp & Dohme (MSD)
Rahway, NJ4 days ago- ...Senior Principal Scientist leading nonclinical drug safety strategy for immunology programs at Merck. Responsible for overseeing development progression... ...oversight and mentorship to compound leaders and program teams, guiding resolution of complex development issues...Principal
Merck
Rahway, NJ6 days ago $190.8k - $300.3k
...DescriptionDescriptionThe Senior Director (Sr. Principal Scientist), Regulatory Affairs Liaison reports to... ...point of contact on those project teams and independently interact with... ...regulatory advice as the Global Regulatory Lead to Product Development Teams and regulatory...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ4 days ago$190.8k - $300.3k
...Senior Principal Scientist in Regulatory Affairs at Merck responsible for developing and implementing... ..., and leadership of regulatory teams to optimize labeling and accelerate product... ...approval Serve as global regulatory lead and single point-of-contact for assigned...PrincipalWorldwideMerck
Rahway, NJ6 days ago$173.2k - $272.6k
...treatment of diseases in people and animals.We are seeking a Principal Scientist to join our Analytical Commercialization Technology (... ...Point, PA sites. This is an exciting opportunity to lead a highly collaborative team of scientists utilizing innovative analytical...PrincipalFull timeFor contractorsLocal areaFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ4 days ago$142.4k - $224.1k
Job DescriptionAssociate Principal Scientist, Regulatory CMC, Synthetic Moities of ADCs & BioconjugatesThis... ...limited to:Serve as a Regulatory CMC Lead for the Synthetic-Moiety (Drug-Linker)... ...Regulatory and on cross-functional teams. Be accountable for the delivery of all...PrincipalFull timeFor contractorsLocal areaMerck Sharp & Dohme (MSD)
Rahway, NJ2 hours ago$156.9k - $247k
Job DescriptionAssociate Principal Scientist/Associate Director, V&I Outcomes Research, HIVRole SummaryThe Associate Principal Scientist/Associate... ...strategy and programs.In collaboration with internal teams and external partners, designs studies; authors study protocols...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ4 days ago- ...Principal Scientist role in Biostatistics leading late-stage clinical development projects. Provides statistical expertise for drug and vaccine development, manages cross-functional teams, and ensures compliance with regulatory requirements throughout the clinical trial...PrincipalWorldwide
Merck
Rahway, NJ6 days ago $142.4k - $224.1k
...Development division, quantitative scientists, in partnership with other... ...human health.The Associate Principal Statistical Programmer,... ...and consulting with project teams, outreach to external vendors... ...Experience contributing to or leading Standards governance forums influencing...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ3 days ago$173.2k - $272.6k
...Principal Scientist position in regulatory affairs for immunology programs at Merck, responsible... ...leadership of cross-functional regulatory teams. Responsibilities Develop and... ...approvals Serve as global regulatory lead and single point-of-contact for assigned...PrincipalWorldwideMerck
Rahway, NJ6 days ago$173.2k - $272.6k
Job DescriptionThe Director (Principal Scientist), Global Regulatory Liaison reports to the Executive... ...point of contact on those project teams and interact with Worldwide Regulatory... ...expert advice as the Global Regulatory Lead to Product Development Teams and regulatory...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ2 days ago$260.3k - $409.7k
...Cardiovascular Disease and related conditions. The Principal Scientist (Clinical Director) must have a strong... ...strategies through cross-functional teams that provide line-of-sight from First-... ...clinical and biomarker plans for Lead Optimization programs, early clinical...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hoursMerck Sharp & Dohme (MSD)
Rahway, NJ2 hours ago- ...Merck's Sterile Product Development group seeks an Associate Principal Scientist to lead biologics formulation and process development from... ...experiments, characterizing drug products, managing cross-functional teams, and advancing innovation in non-oral dosage forms....Principal
Merck
Rahway, NJ6 days ago $173.2k - $272.6k
...Merck seeks a Principal Scientist to lead analytical chemistry efforts for small molecule drug product development and commercialization. The role involves managing a team, conducting method development and validation, supporting regulatory submissions, and mentoring scientists...PrincipalMerck
Rahway, NJ6 days ago- ...Principal Scientist role in oral formulation development within Merck's Pharmaceutical Sciences and Clinical Supply organization. Leads CMC project teams and formulation development from early-stage first-in-human through market formulation, while driving technology strategy...Principal
Merck
Rahway, NJ6 days ago - ...Merck seeks a Senior Principal Scientist to lead upstream bioprocess development for the Biologics platform. This role combines scientific expertise... ...innovation across pipeline projects and directing a team of 3-5 scientists. Responsibilities Drive innovation...Principal
Merck
Rahway, NJ6 days ago
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Scientist - Multiscale Separations Team Lead. Be the first to apply!
Related searches