Sr Senior Scientist - Autoimmunity, Immunology and Inflammation

Do you want to help uncover the biology behind inflammatory and autoimmune diseases—and turn those insights into medicines that could change patients’ lives? Regeneron’s Immunology and Inflammation team is seeking a Senior Scientist to lead innovative research programs that connect deep mechanistic biology with therapeutic discovery. In this role, you will shape experimental strategy, design rigorous in vitro and in vivo studies, interrogate novel immune pathways, and collaborate with talented scientists across disciplines to advance high-impact programs in Regeneron’s pipeline. This is an opportunity for a creative, hands-on, hypothesis-driven scientist to do ambitious science in a collaborative environment where strong ideas can rapidly influence drug discovery.

In this role, you will have the opportunity to:

• Lead complex in vivo studies in mouse models of inflammatory disease to evaluate therapeutic efficacy, define mechanism of action, and generate decision-enabling data.

• Build and optimize primary cell-based assays and high-content immunological readouts, including multi-parameter flow cytometry, ELISA/MSD, and histology, to interrogate cytokine and immunoreceptor pathways.

• Influence project direction by interpreting complex datasets, integrating emerging literature, and communicating clear scientific recommendations to project teams, leadership, and external collaborators.

• Mentor junior scientists and research associates while contributing to an inclusive, collaborative culture that values scientific rigor and curiosity.

This role could be a great fit if:

• You are an independent, hypothesis-driven scientist who enjoys shaping research questions, designing rigorous experiments, and troubleshooting complex programs from concept through readout.

• You are energized by cross-functional collaboration and know how to partner across disciplines to move discovery programs forward.

• You bring deep immunology expertise, strong analytical thinking, and the ability to translate complex data into clear scientific conclusions.

• You are intellectually curious, adaptable, and comfortable learning new approaches as scientific questions and program priorities evolve.

• You are motivated by the chance to connect discovery science with therapeutic impact for patients.

To be considered for this role, you should have a PhD in Immunology, Biology, Cellular and Molecular Biology, or a related discipline, or an MS with at least 8 years of relevant industry or academic research experience. Hands-on expertise with mouse models of inflammatory diseases, multi-parameter flow cytometry, primary cell culture and cell-based assays, ELISA/MSD, and standard molecular techniques is required. A strong peer-reviewed publication record and demonstrated ability to lead independent research programs are essential.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)