Director, Protein Sciences

Responsibilities Lead evaluation of therapeutic targets, including structural, sequence, and domain architecture analysis. Integrate internal and external data (literature, databases, structural repositories). Define antigen and engineered-cell design strategies to support antibody discovery: construct design and domain selection, epitope exposure and conformational state optimization, strategies for difficult targets (e.g., multi-pass membrane proteins) including nanodisc technology and nucleic acid immunogen design. Apply computational and structural biology approaches to protein design: homology modeling, structural analysis, and rational mutagenesis. Integrate emerging AI/ML-based protein design tools. Engineer proteins to improve stability and expression, functional relevance for discovery assays and immunization. Requirements A minimum of a Ph.D. in Biochemistry, Structural Biology, Protein Engineering, or a related discipline. A minimum of 10 years of experience in biologics discovery or protein sciences. Demonstrated leadership experience within the pharmaceutical or biotech industry. Strong knowledge in: antigen design and generation for antibody discovery; structural biology and protein sequence analysis; biologics discovery workflows from target to lead identification. Experience or domain knowledge in Oncology, Immunology, and/or Neuroscience is preferred. People management experience is preferred. Excellent verbal and written communication skills. Strategic with a strong scientific mindset. Ability to operate effectively within a highly coordinated, fast-paced matrix environment. Core Competencies Expertise in protein engineering and structural biology, with a strong focus on antigen design and biologics discovery workflows. Proven leadership in the pharmaceutical or biotech industry, complemented by excellent communication skills and the ability to thrive in fast-paced environments. #J-18808-Ljbffr Jobtailor