Medicinal Chemist (IPMs/PROTACs) for First-in-Class Drugs
General Proximity
General Proximity, a seed-stage startup located in San Francisco, is seeking a talented medicinal chemist to join our Chemistry/Drug Discovery Team. In this role, you'll design and optimize novel bifunctional molecules while collaborating with cross-functional teams. Ideal candidates will hold a PhD and have proven skills in drug discovery and medicinal chemistry. We offer significant equity incentives and top-tier medical benefits, promoting a healthy work-life balance. #J-18808-Ljbffr General Proximity
- ...generation of induced proximity medicines (IPMs). Our OmniTAC drug discovery engine... ...decades. We are seeking a first-rate medicinal chemist to help us pioneer this... ...of a completely novel class of therapeutics. Your responsibilities... ...medicines (e.g. PROTACs or other IPMs) Hit-to-...Suggested
- University of California, San Francisco seeks creative medicinal chemists to join the Institute for Neurodegenerative Diseases as part of an Adjunct Professor series. The role focuses on driving drug discovery programs for Alzheimer's, Parkinson's, and other neurodegenerative...Suggested
- A renowned educational institution in San Francisco seeks experienced Medicinal Chemists for adjunct faculty positions in drug discovery programs, particularly in Alzheimer's disease and related conditions. Candidates must hold a Ph.D. and demonstrate creative molecular...SuggestedFull time
- Lilly is seeking a Postdoctoral Scientist in South San Francisco to join the Medicinal Chemistry organization within LSMD. You will work on drug-discovery projects, applying synthetic expertise to design and prepare novel targets while contributing to method development...Suggested
- ...the team building the first accurate AI systems for... ...important questions in drug discovery: Given a molecule... ...needs shape the world‑class datasets we build from... ...outcomes. Use medicinal chemistry intuition to... ...workflows for medicinal chemists and toxicologists. Help...Suggested
- ...only be considered if the position has not yet been filled. Medicinal Chemists/Adjunct Professor Series The Institute for Neurodegenerative... ...highly motivated medicinal chemists to help drive the IND's drug discovery programs in Alzheimer's disease, frontotemporal dementia...Full timeContract workLocal area
$112.5k - $297.2k
...Medicinal Chemists/Adjunct Professor Series The Institute for Neurodegenerative Diseases (IND) at the University of California, San Francisco... ...highly motivated medicinal chemists to help drive the IND's drug discovery programs in Alzheimer's disease, frontotemporal...Full timeContract workTraineeshipWorldwide$112.5k - $297.2k
Medicinal Chemists / Adjunct Professor Series The Institute for Neurodegenerative Diseases (IND) at the University of California, San Francisco... ...highly motivated medicinal chemists to help drive the IND’s drug discovery programs in Alzheimer’s disease, frontotemporal...Full time- Capable Labs is seeking an experienced medicinal chemist to lead design and synthesis across small‑molecule and peptide programs. You will own chemistry end to end, from target selection to biological handoff, while leveraging SAR and in vitro/in vivo data to steer next...Visa sponsorship
- Capable is seeking an experienced medicinal chemist in San Francisco to lead design and synthesis across diverse programs. You will own end‑to‑end chemistry, from target selection through purification and preparation for biological testing, while troubleshooting challenges...
- ...Biology Team. You will collaborate with our Platform and Chemistry Teams, driving the mechanistic understanding of our next-generation drugs and supporting core drug discovery efforts. Ideal candidates will have a strong background in cellular and molecular biology, with...
- ...It starts with deeply understanding the needs of drug hunters inside large pharma. Those needs shape the world‑class datasets we build from scratch. We then use that... ...hit‑to‑lead, lead‑op, or candidate nomination. Medicinal chemistry reasoning around structure-activity...
- BioSpace is looking for an analytical chemist to oversee discovery analytical work at their South San Francisco headquarters. The role involves... ...have a Ph.D. in analytical chemistry and at least five years of drug discovery experience, with a strong background in small-molecule...
$125k
...wellness Competitive salary and first-employee equity package... ...for “Research And Development Chemist” roles. Oakland, CA $97,000.00... ...weeks ago Intern - Synthetic and Medicinal Chemistry Senior Chemist, Scientist... ...Scientist, Small-Molecule Drug Substance Development and Manufacturing...Full timeContract workInternship- IDEAYA Biosciences seeks a Senior Principal Research Scientist in Computational Chemistry to advance its drug discovery programs. This role involves leading drug design efforts, applying computational methods, and mentoring team members. The ideal candidate holds a PhD...
$145k - $220k
...demonstrates the judgment, rigor, and follow‑through to move important work forward can earn meaningful scope. What You’ll Do Lead medicinal chemistry design and synthesis across small‑molecule, peptide, and peptide‑adjacent programs, from target compound selection...H1bVisa sponsorship- ...firm is seeking a Senior Principal Scientist in Medicinal Chemistry to design novel compounds and lead PhD-level chemists. This role involves managing external teams and... ...with a diverse team to advance the drug development pipeline. The ideal candidate will...Flexible hours
- ...therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease—we reach millions of patients each... ...PTR). Recruit top talent and lead several PhD‑level chemists in the design and synthesis of potential drug candidates. Provide motivating professional...Full timeRemote workFlexible hours
- Genentech in South San Francisco seeks a highly skilled computational chemist to drive induced proximity small molecule discovery,... ...advanced modeling (molecular dynamics, docking), apply AI/ML in drug discovery, and coordinate with Structural Biology, Biochemical Pharmacology...
$135k - $180k
...improve the success rate of drug discovery and development. One... ...data-oriented DEL synthetic chemist to lead lab-based DEL synthesis... ...methods Collaborate with our Medicinal Chemistry and Machine... ...selections to various protein classes Contribute to the analysis of...Full timeHome officeFlexible hours$167k - $206k
...Summary IDEAYA is a precision medicine oncology company committed to... ...expertise in small‑molecule drug discovery, structural biology... ...develop tailored, potentially first‑in‑class, targeted therapies aligned... ...studies Manage junior analytical chemist(s) to achieve strong...Temporary workShift work$196k - $242k
...Summary IDEAYA is a precision medicine oncology company committed to... ...expertise in small‑molecule drug discovery, structural biology... ...develop tailored, potentially first‑in‑class targeted therapies aligned to... ...experienced computational chemist with a strong track record of...Temporary workWork at officeLocal areaWork from home$229k - $269k
...Overview Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted... ...seeking a Senior Machine Learning Scientist to help accelerate drug discovery through advanced analytics and artificial...Full timeLocal area- ...performs professional pharmaceutical duties in drug education and utilization, counsels... ...utilization, and may compound drugs and dispense medicines in a clinical pharmacy. The essential... ...as a Clinical Pharmacist (equivalent to class 2454 Clinical Pharmacist within the City...Full timeWork experience placement
$191.85k - $244.84k
Department: Public Health Job class: 2454-Clinical Pharmacist Salary range: $191,854.0... ...performs professional pharmaceutical duties in drug education and utilization, counsels... ...utilization, and may compound drugs and dispense medicines in a clinical pharmacy. The essential...Permanent employmentFull time$132k - $166k
Revolution Medicines in San Francisco is seeking a Scientist II for its Drug Product team. The role involves contributing to the development of solid oral dosage forms for small molecule programs. Candidates should have a Ph.D. with relevant experience or a Bachelor's/Master...$167.4k - $310.8k
...Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early... ...both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. The Opportunity At Roche's AI for Drug...Local areaWorldwideRelocation package$170k - $212k
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers... ...Playing a critical role as a technical lead within the Drug Substance function, the position will be responsible for process...Work experience placement$147.8k - $274.4k
...computational sciences are transforming drug discovery and development. Roche’s Research... ...more innovative and transformative medicines for patients worldwide. The Opportunity... ...research experience, including at least one first author publication or equivalent. Strong...Work experience placementLocal areaWorldwideRelocation package$220k - $315k
...real-world applications in precision medicine, digital pathology, drug discovery, and more. Core responsibilities... ...our values: Put mission and team first All we do is in service of our... ...groundbreaking technology with a world-class team dedicated to ensuring a safe and...
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