DMPK Scientist - PK/PD Modeling & ADME Strategy
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals in Cambridge, MA seeks a DMPK Scientist to design and interpret ADME and PK/PD studies for siRNA and other modalities, applying quantitative pharmacology to guide candidate selection and human dose predictions. The role demands expertise in non-compartmental and compartmental analysis, PBPK, and systems pharmacology, with strong communication and teamwork within a fast-paced environment. #J-18808-Ljbffr Alnylam Pharmaceuticals
- ...quality biotherapeutics development go hand in hand. As a Scientist, PK/PD Modeling & Simulation, you will be responsible for developing, validating... ...will be central to integrating modeling and simulation strategies into Hemab’s clinical programs and advancing our mission...Suggested
- Zealand Pharma in Cambridge, MA seeks a Principal Scientist to lead the DMPK/ADME strategy for complex drug modalities and to build discovery platforms and... ...excellence from the ground up. You will oversee PK studies, deliver integrated DMPK summaries, and drive digital...Suggested
$110.4k - $165.6k
Overview:The mission of DMPK is to enable... ...and interpreting ADME (absorption, distribution... ...excretion) and PK/PD (pharmacokinetics/... ...pharmacology and modeling, consequently... ...highly motivated scientists across a broad array... ...Responsibilities:Support DMPK strategy across drug...SuggestedFull timeTemporary workLocal areaFlexible hours$147.2k - $220.8k
.../pharmacodynamic (PK/PD) relationships of... ...Development as a Principal Scientist within Drug... ...Pharmacokinetics (DMPK), providing... ...and implement DMPK strategies to support discovery... ...metabolism, excretion (ADME), PK/PD... ...approaches, including modeling and simulation, to...SuggestedFull timeTemporary workWork at officeLocal areaFlexible hours$119.7k - $222.3k
...enthusiastic and motivated PK Sciences... ...intelligence (AI) enabled strategies to transform... ...Drug Disposition (ADME, BA), Modeling & Simulation (M&S)... ...and clinical PK/PD relationships and... ...role overseeing ADME/DMPK project strategy... ...considered for Principal Scientist II. 4+ years of...SuggestedFull time$157k - $213k
...motivated and detail-oriented Scientist with strong expertise... ...and Pharmacokinetics (DMPK) sciences to support... ...pharmacokinetic (PK), toxicokinetic (TK),... ...in vivo studies (i.e., ADME, PK, PK/PD) to support advancement... ...-on experience with modeling and simulation is a plusPay...Contract workTemporary workSummer workWork at officeLocal area$176.2k - $277.3k
...collaborative Principal Scientist (director-level... ...interpretation of PK and PK/PD data sets and... ...Lead bioanalytical strategies for a portfolio of... ...multiple modality DMPK activities within... ...pharmacokinetic (PBPK) software modeling (e.g., Phoenix... ...Skills: ADME, Bioanalysis, Bioanalytical...Full timeFor contractorsLocal areaWorldwideFlexible hours$179k - $236k
...Scientific Officer, this role leads DMPK and bioanalytical strategy across nonclinical and clinical... ...DMPK and bioanalytical scientist with experience in PK study design, bioanalytical method... ...PK, biomarker, and translational PD readoutsLead method development,...- ...Position The Senior Scientist, DMPK will provide... ...candidates by integrating DMPK strategy across multiple therapeutic... ...experimental and modeling approaches to de risk... ...pharmacokinetic/pharmacodynamic (PK/PD) modeling and/or... ...global Novo Nordisk ADME experts to harmonize...Local areaFlexible hours
- ...Beacon-1 ADMET prediction models, human dose projection tools... ...and cost-effective tier 1 ADME panels that enable initial human PK projection, closing the... ...Alongside outstanding compchem, DMPK, and machine learning... ...you think about synthetic strategy, you look for convergent routes...
$146k - $236k
...portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms... ...impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World...$115k - $209k
...companies. As part of Flagship’s integrated model of science, entrepreneurship, and... ...Position Summary We are seeking a (Senior) Scientist to join Pioneering Intelligence (PI), a... ...house expert in clinical and commercial strategy, and will lead the codification of therapeutic...Casual work- ...PK Sciences Project Team Representative We are seeking an enthusiastic and motivated... ...translational or clinical pharmacology strategies to support the pursuit of... ...Science disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations through...
- ...motivated and accomplished scientist to lead the Bioanalytical (BioA) and PK/PD function. This role is... ...pharmacokinetic modeling to translate data into actionable... ...Bioanalytical and PK/PD strategies for ADC programs,... ...Oversee in vitro and in vivo ADME studies, including payload...
$192k - $265k
...Biomedicines is seeking a creative, rigorous, and execution-oriented machine learning scientist to join our Model-Driven Design team. This role will focus on building the ML methods, data strategies, and closed-loop systems that determine what we design, build, test, and learn...Work at officeShift work$114.1k - $211.9k
...motivated and scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker representative and strategic... ...milestones.Develop integrated biomarker plans encompassing assays, models, samples, analyses, timelines, and external partnerships....Full timeLocal areaFlexible hours$108k - $128k
...Principal Associate Scientist Parabilis Medicines is a clinical-stage... ...blot across 2D and 3D cell models. Develop, optimize, and qualify... ...with Translational Biology, DMPK and in vivo Pharmacology... ...cellular findings into tissue PK/PD and biomarker studies where appropriate...Shift work$170k - $200k
...stability, permeability, and ADME/PK properties; and using multiparameter... ...to integrate computational modeling, structural information,... ...biophysics, structural biology, DMPK and biology design molecules... ...and passionate team of scientists ~ Be a part of a cutting-...$184.2k - $253.2k
Does it excite you to translate DMPK insights into the design and... ...have experience leading DMPK/ADME strategy in a fast-moving R&D... ..., we are seeking a Principal Scientist to take a leading scientific... ...MS, immunoassays) to support PK, metabolite identification, and...$176.2k - $277.3k
...Principal Scientist position in pharmacokinetics, dynamics... ...matter expert on DMPK activities across oncology... ...spectrometry-based bioanalytical strategies Contribute to global... ...strategies and analyze ADME and pharmacokinetic... ...to translational PK/PD/efficacy relationships...- ...off Stock options plan Scientist/Senior Scientist, Biology Lead... ...relevant kidney disease models to build and lead our kidney... ...functional knockdown ü In vivo PK/PD, biodistribution, efficacy,... ...therapeutic hypotheses, delivery strategies, and biomarker plans ·...
- ...Generate Biomedicines seeks a machine learning scientist to develop methods and systems for lab-... ...decision-making and data-driven design strategies. Responsibilities Develop machine... ...protein optimization including property models and multi-objective strategies Design...
$161k - $186k
...it most.We are seeking a Senior Scientist/Manager, Clinical Bioanalysis to... ...clinical implementation of bioanalysis strategy in partnership with internal... ...of the clinical studies.Support DMPK bioanalysis activities, including PK, ADA, and PD biomarker integration, for...Work at office- ...50,000 planners, designers, engineers, scientists, digital innovators, program and construction... ...is seeking a dynamic Economics and Strategy Advisory Consultant to support our growing... ...analysis, such as microeconomic modelling, econometric estimations and cost-benefit...Work at officeLocal areaWorldwideRelocation packageFlexible hours
$80k - $130k
...motivated and detail-oriented scientist to join our dynamic in... ...pharmacology studies in rodent models relevant to oncology,... ...efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of new compounds. Perform... ...to optimize therapeutic strategies. Analyze and present data...Full timeWork at office$100k - $120k
...StealthCo - Associate Scientist, In Vitro Pharmacology... ...translatability from animal models to humans, which... ...target engagement and PD effect across delivery... ...biodistribution data anchoring PK/PD interpretation In... ...with the team’s biomarker strategy, develop and implement...Shift work- ...Research Scientist Position at Basis Research scientists lead Basis' efforts to develop a deeper understanding of the conceptual, mathematical... ...increasing recognition that both having and discovering world models are central to intelligence, current AI systems struggle to...Full timeWork at officeImmediate start
$141k - $188k
...a highly motivated Principal Scientist to contribute to the development... ...biomarker and bioanalytical strategies supporting discovery, translational... ...bioanalytical approaches (PK, ADA) and support the implementation... ...of Biomarker methods (TE, PD, Disease) supporting the...Full timeTemporary workLocal areaFlexible hours$126k - $234k
...radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team in... ...development and application of in vivo models for evaluating novel cancer therapies and... ...of in vivo anti-tumor efficacy and PK/PD studies aimed at evaluating drug candidates...Full timeRemote work$137k - $215.27k
...seeking a skilled cheminformatic scientist to join Takeda’s... ...teams in medicinal chemistry, DMPK, and AI/ML, defining a roadmap... ...acceleration. Build predictive models for molecule design and optimization... ...of innovative chemistry strategies that meet Takeda’s therapeutic...Minimum wageLocal area
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