Senior Translational PK/PD Modeling Director
Scorpion Therapeutics
Scorpion Therapeutics is seeking a Translational PK/PD Scientific Associate Director in Boston to lead model-based decisions across discovery and translational programs. You will integrate diverse data, build PBPK/QSP platforms, and help shape translational strategy for dose projections and human pharmacology. The role requires advanced degrees and hands-on experience with PK/PD modeling in biologics/peptides, plus expertise in experimental design and statistics. #J-18808-Ljbffr Scorpion Therapeutics
- Scorpion Therapeutics in Boston seeks a Translational PK/PD Senior Scientist to drive model-informed decisions across drug discovery and dose prediction. The role integrates PKPD modeling with experimental data, supporting forward and reverse translation and informing modality...Senior
$156.9k - $247k
...(PDMB) is seeking a curious and collaborative Scientific Associate Director for our growing Translational PK/PD organization. The Translational PK/PD Associate Director is an expert mathematical modeler and scientist who independently designs and executes analyses with...SuggestedFull timeFor contractorsLocal areaFlexible hours- The Translational PK/PD Scientific Associate Director will: Serve as expert PK/PD modeler in cross-functional teams to make model-informed decisions about drug discovery, modality selection, and dose prediction. Integrate in vitro and in vivo data to build PK/PD, PBPK,...Suggested
$129k - $203.1k
The Translational PK/PD Senior Scientist will: Serve as PK/PD modeler in cross-functional teams to support model-informed decisions on drug discovery, modality selection, and dose prediction. Integrate in vitro and in vivo data to build PKPD, PBPK, QSP, and other mechanistic...Senior$129k - $203.1k
...Metabolism & Bioanalytics (PDMB) is seeking a curious and collaborative Senior Scientist for our growing Translational PK/PD organization. The Translational PK/PD Senior Scientist is a skilled mathematical modeler and scientist who designs and executes analyses, with...SeniorFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$152.6k - $283.4k
...therapies. We are seeking a translational modeler eager to accelerate oligonucleotide... ...(QSP) and mechanistic PBPK/PD approaches to inform key... ...and apply mechanistic models (PK/PD, QSP, and PBPK/PD) that link... .... A modeler at the Associate Director level will have additional...Full time$240k - $389.4k
...partners and patients.Purpose of the Role:The Senior/Executive Director [commensurate with experience], ExploR&D Translational Medicine incumbent is responsible for the... ...dose ranges and in interpreting emerging human PK/PD data to inform dose escalation and dose regimen...SeniorLocal areaRemote workFlexible hours- Novartis Group Companies in Cambridge, MA is seeking an Associate Director in Translational Modeling to lead M&S strategies across programs, building mechanistic PK/PD, QSP, and PBPK/PD models that connect pharmacology to clinical outcomes. You will collaborate with discovery...
- Merck in Boston, MA is seeking a Translational PK/PD Senior Scientist to design and execute modeling analyses that guide drug discovery for biologics, proteins and peptides. You will serve as a PK/PD modeler in cross-functional teams and help shape dose predictions and...Senior
- ...partners and patients. Purpose of the Role: The Senior/Executive Director [commensurate with experience], ExploR&D Translational Medicine incumbent is responsible for the... ...ranges and in interpreting emerging human PK/PD data to inform dose escalation and dose regimen...Senior
- Merck is seeking a Senior Director at our Boston Research Labs to lead protein therapeutic efforts from discovery to first-in-human trials. This role will involve overseeing pharmacokinetic studies and managing a talented team of scientists while collaborating cross-functionally...Senior
- Amylyx Pharmaceuticals is seeking a Senior Director, Clinical Pharmacology to provide strategic scientific leadership across... .... The successful candidate will lead deep PK/PD, exposure-response analyses, modeling and simulation, and study design, while mentoring #J...Senior
- Amylyx Pharmaceuticals, Inc. is seeking a Senior Director, Clinical Pharmacology to provide strategic leadership from early to late-stage trials. Lead PK/PD, exposure-response analyses, and modeling across programs, partnering with Clinical Development, Biometrics, Regulatory...Senior
- Eli Lilly and Company seeks a Senior/Executive Director of ExploR&D Translational Medicine for medical strategy across multiple early assets. You will lead cross... ...for early-phase programs, with a hybrid work model in Boston, MA, or Indianapolis, IN. #J-18808-Ljbffr...Senior
$126k - $234k
...Title: Principal Scientist II or Senior Principal ScientistLocation:... ...therapies. We are seeking a translational modeler eager to accelerate... ...pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key... ...and apply mechanistic models (PK/PD, QSP, and PBPK/PD) that link...SeniorFull time$119.7k - $222.3k
...enthusiastic and motivated PK Sciences representative... ...work seamlessly in the translational and/or clinical space,... ...(ADME, BA), Modeling & Simulation (M&S), and... ...nonclinical and clinical PK/PD relationships and development... ...to be considered for Senior Principal Scientist....SeniorFull time- ...-driven organization focused on translating innovative discovery concepts into... ...We are seeking an experienced Director or Sr. Director of Nonclinical Toxicology & PK to provide scientific leadership... ...WinNonlin) and oversee advanced PK modeling and FIH starting‑dose rationale...SeniorRemote job
$194.1k - $305.6k
...thinking and collaborative Senior Director to contribute to our Company... ...and operational oversight for PK/PD and bioanalytical activities... ..., nonclinical drug safety, translational medicine and therapeutic area... ...pharmacokinetic (PBPK) models (e.g., Phoenix WinNonlin, Berkeley...SeniorFull timeFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$210.4k - $331.1k
...Pharmacometrics -Oncology (QP2 Oncology) team as Senior Director, Quantitative Systems Pharmacology (... ...clinical pharmacology, mechanistic PK-PD modeling and pharmacometrics of oncology drugs... .... Partner with senior leaders in Translational Modeling, Discovery and Clinical...SeniorFull timeContract workFor contractorsLocal areaRemote workRelocationVisa sponsorshipFlexible hoursShift work$146k - $236k
...portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms... ...Pioneering Intelligence (PI) is building AI systems that accelerate translational decision making. This forward-deployed role bridges the gap...Senior$176.4k - $327.6k
...Hybrid Internal Title: Executive Director / DirectorLocation:... ...is a leader in mechanistic modelling and simulation. We are seeking... ...Modeling & Simulation (M&S) within Translational Medicine in Biomedical... ...systems biology, integrative PK/PD-disease frameworks) to understand...Full time$195k - $330k
...inviting curiosity and inclusivity, so that our people are valued, seen, and heard.How you’ll make an impact:Serves as an Immunology Translational Medicine Program Lead on cross-functional project team(s) and develops translational medicine and biomarker strategies to...Senior$196.7k - $353.4k
...strategic leader to serve as Senior Director, Head of Quantitative... ...vision for how mechanistic modeling, systems biology, and model-... ...development decisions, strengthen translational understanding, and optimize... ...clinical).Deep understanding of PK/PD, systems biology, disease...SeniorPermanent employmentFull timeWork at officeWork from home- Pinetree Therapeutics is seeking a Director/Senior Director of Nonclinical Toxicology & PK to lead integrated safety and PK strategies across multispecific antibody programs. The role involves independent ownership of nonclinical safety, tissue cross-reactivity assessments...SeniorRemote job
- ...clinical‑stage biotech, seeks a Sr. Principal Scientist / Director of DMPK & Bioanalytical Sciences to lead DMPK and... ...fast‑paced environment. This hands‑on role drives PK/PD study design, assay development, and translational biomarker strategy with CRO oversight. The...Senior
- ...Therapeutics in San Diego seeks an Associate Director, Clinical Pharmacology to design, lead,... ...communicate key pharmacology concepts to senior management, regulatory agencies, and... ...(or PharmD with 8+ years), demonstrated PK/PD leadership, dose and regimen guidance, and...Remote job
- Kymera Therapeutics is seeking an Immunology Translational Medicine Program Lead to develop translational medicine and biomarker strategies for early and late-phase trials. The role involves cross-functional collaboration with Medicine, Clinical Operations, and external...Senior
$170k - $230k
...with Platform Discovery Sciences, Translational Medicine and program teams to utilize and interpret animal models of diseases for efficacy/tolerability assessment and PK/PD evaluation. Lead the... ...guidance to project teams and senior management including evaluation...Temporary workSummer workLocal area$202.4k - $323.4k
Your Impact at LILA The Director, Molecular Discovery is... ...ensure that process translates into real, high-quality... ...at least 5 years in a senior role closely involved in... ...potency, selectivity, ADMET, PK, safety) well enough to... ...don't need to build models, but you must be a...SeniorFull timeWork at officeFlexible hours$160k - $275k
...standards, best practices, and software strategy.Apply translational PBPK/PBBM to predict human PK and oral bioavailability across species, formulations,... ...IVIVC and mechanistic in vitro-in vivo dissolution models (e.g., DDDPlus) to link drug product performance to in...
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