Associate Director, Translational PK/PD
Scorpion Therapeutics
The Translational PK/PD Scientific Associate Director will: Serve as expert PK/PD modeler in cross-functional teams to make model-informed decisions about drug discovery, modality selection, and dose prediction. Integrate in vitro and in vivo data to build PK/PD, PBPK, QSP, or other mechanistic modeling platforms for drug disposition and pharmacology to support forward/reverse translation. Collaborate to design experimental studies and modeling plans to identify and optimize drug candidates and guide translational strategy. Guide automated workflows for implementing modeling platforms to inform human PK/PD and dose projections. Provide scientific and modeling guidance to junior colleagues. Qualifications: Education: Master’s (8+ years), PharmD (6+ years), or Ph.D. (4+ years) in pharmacokinetics/pharmacodynamics, mathematics, applied mathematics, systems/computational biology, chemical/biomedical engineering, statistics/biostatistics, or related field. Required experience/skills: Hands-on translational PK/PD modeling using standard software (e.g., Matlab, OSP Suite, Monolix, R) for biologics/protein therapeutics and/or peptides. Expert skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics. Preferred: Experience in interdisciplinary teams and collaborative problem scoping/planning. Expertise developing novel translational modeling strategies or automated workflows using PBPK, QSP, or related mechanistic modeling. Skills: Biologics Biostatistics Data Analysis/Modeling/Data Science Drug Discovery Process Interdisciplinary Collaboration
MATLAB
Peptides Pharmacodynamics/Pharmacokinetics/Pharmacotherapeutics PK/PD Modeling Proteins Statistical Analysis Translational PK/PD #J-18808-Ljbffr Scorpion Therapeutics$156.9k - $247k
...Pharmacokinetics, Dynamics, Metabolism & Bioanalytics (PDMB) is seeking a curious and collaborative Scientific Associate Director for our growing Translational PK/PD organization. The Translational PK/PD Associate Director is an expert mathematical modeler and scientist...SuggestedFull timeFor contractorsLocal areaFlexible hours- Scorpion Therapeutics is seeking a Translational PK/PD Scientific Associate Director in Boston to lead model-based decisions across discovery and translational programs. You will integrate diverse data, build PBPK/QSP platforms, and help shape translational strategy for...Suggested
- Travere Therapeutics in San Diego seeks an Associate Director, Clinical Pharmacology to design, lead, and implement clinical pharmacology strategies... ...a PhD or equivalent (or PharmD with 8+ years), demonstrated PK/PD leadership, dose and regimen guidance, and experience with...SuggestedRemote job
$152.6k - $283.4k
...Hybrid Internal Title: Associate DirectorLocation: Cambridge... .... We are seeking a translational modeler eager to accelerate... ...) and mechanistic PBPK/PD approaches to inform... ...mechanistic models (PK/PD, QSP, and PBPK/PD) that... ...at the Associate Director level will have additional...SuggestedFull time- Novartis Group Companies in Cambridge, MA is seeking an Associate Director in Translational Modeling to lead M&S strategies across programs, building mechanistic PK/PD, QSP, and PBPK/PD models that connect pharmacology to clinical outcomes. You will collaborate with discovery...Suggested
$170k - $230k
...data and study reports. Work with Platform Discovery Sciences, Translational Medicine and program teams to utilize and interpret animal models of diseases for efficacy/tolerability assessment and PK/PD evaluation. Lead the development of early hypothesis-driven investigation...Temporary workSummer workLocal area$175.8k - $237.8k
Associate Director, Quantitative Systems PharmacologyOverview The Associate Director, Quantitative... ...pharmacology, clinical pharmacology, PK and PD with ability to critically evaluate... ...MATLAB, Simbiology etc.Experience in translating and summarizing QSP modeling outcomes...Full timeTemporary workLocal areaFlexible hours$156.9k - $247k
...welcome a curious, collaborative, and scientifically driven Associate Director to help support our growing cardiometabolic pipelines.In... ...:Develop and apply model-based strategies, including translational PK/PD approaches, mechanistic models, population PK/PD analyses...Full timeFor contractorsLocal areaFlexible hours$160.3k - $297.7k
...Description Summary#LI-Hybrid Internal Title: Associate DirectorLocation: Cambridge, MANovartis... ...(PKS) Modeling & Simulation (M&S), Translational Medicine, and multidisciplinary project... ...learning with mechanistic modelling (e.g., PK/PD, QSP) to support decision-making from...Full time$240k - $389.4k
...patients.Purpose of the Role:The Senior/Executive Director [commensurate with experience], ExploR&D Translational Medicine incumbent is responsible for the overarching... ..., dose ranges and in interpreting emerging human PK/PD data to inform dose escalation and dose regimen...Local areaRemote workFlexible hours$165k - $200k
...experienced scientist to provide scientific leadership and apply PK/PD principles to our portfolio of exciting peptide drugs.... ...outcomes, and all energy in the company is focused on science as it translates to patient impact. All-In. We're All-In on solving some of...Shift work$176.1k - $287.3k
...We are seeking a highly motivated Associate Director (AD) to join the Quantitative Pharmacology... ...Pharmacology, Biostatistics, Clinical and Translational teams to support regulatory and... ...accountable for timely delivery of population PK/PD, exposure–response, and translational...Remote work- Responsibilities: Develop and apply model-based strategies (translational PK/PD, mechanistic models, population PK/PD, and clinical trial simulations) to support quantitative decision-making (dose selection, trial design, go/no-go). Represent QP2 on cardiometabolic discovery...
- Jobtailor is seeking an experienced biomarker leader to develop translational strategies for clinical development, regulatory paths, and product commercialization in collaboration with cross‑functional teams. You will partner with Research to identify biomarker endpoints...
- Overview: The Associate Director, Quantitative Systems Pharmacology (QSP) supports a clinical portfolio... ...pharmacology, clinical pharmacology, PK/PD, and data analysis to answer drug... ...g., R, MATLAB, Simbiology). Ability to translate QSP outcomes for project teams; strong...
- OverviewThe Research Department at Alnylam is seeking a passionate and creative physician-scientist to join the Translational Research Group to play a key role in guiding the discovery, validation, and prioritization of new therapeutic targets. You will join a highly collaborative...Full timeTemporary workLocal areaFlexible hours
- ...staffingfuture.comPosition Summary The Senior / Associate Director, Clinical Data Manager will lead... ...Development, Safety, Regulatory, Translational Medicine, and external vendors to ensure... ...local laboratory, imaging, safety, PK/PD, biomarker, genomic, and specialty testing...Work at officeLocal area3 days per week
$145k - $240k
...differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.How you’ll make an impact:Lead Translational Medicine (TM) operations for clinical studies, overseeing end-to-end biospecimen management from study start-up through closeout...Contract work$146.3k - $234.1k
...cutting-edge science and innovation. As Associate Director, Clinical Pharmacology &... ...scientific expertise in pharmacokinetics (PK), pharmacodynamics (PD), and pharmacometrics (PMx), and... ...modeling, exposure-response analyses, and translational quantitative pharmacology...Hourly payWorldwide$165k - $200k
...Job Description Job Description Description: Sr. Manager / Associate Director, Late-Phase Drug Substance PD/MSAT At Merida Biosciences, we are pioneering true precision medicines for antibody-driven diseases. We specifically target pathogenic antibodies and their...Local area$183.77k - $275.65k
...Job Title: Translational Medicine Lead, Associate Director, Oncology Location: Cambridge, MA Introduction to role: Are you ready to turn cutting-edge biomarker science into confident clinical decisions that change patient outcomes? As Translational Medicine...Hourly payTemporary workWork at officeFlexible hours3 days per week$146.3k - $234.1k
...data Drive PKPD modeling, exposure-response analyses, and translational quantitative pharmacology activities to support optimal... ...research leads on study design and data interpretation of PK, toxicokinetic and PD aspects of preclinical studies Provide clinical pharmacology...$193.8k - $240.38k
Associate Director / Director, Clinical Pharmacology Watertown, Massachusetts... ...with Clinical Development, Translational Medicine, Biomarkers, and... ...also includes oversight of PK sample strategy, bioanalytical... ...pharmacokinetic (PK), pharmacodynamic (PD), and exposure-response...$174k - $196k
Associate Director, Clinical Pharmacology Cambridge, Massachusetts, United States City Therapeutics... ...to join our dynamic and growing Translational Sciences Team to help shape the... ...leadership for pharmacokinetic (PK), pharmacodynamic (PD), exposure-response, and dose...Work at officeWork from homeFlexible hours- Develop translational biomarker strategies designed to support clinical development plans, the regulatory path, and product commercialization Partner with Research to discover and characterize novel biomarker endpoints in preclinical studies Develop biomarker methods and...
$160k - $275k
...and grow Kymera's PBPK/PBBM capability, defining workflows, standards, best practices, and software strategy.Apply translational PBPK/PBBM to predict human PK and oral bioavailability across species, formulations, and dose levels, and to support first-in-human dose...- ...DescriptionGeneral Summary:The Modeling & Simulations Associate Director will be responsible for developing and... ...mechanism based PKPD and population PK and PKPD-analyses, Clinical trial... ...teams and integrating the use of PK/PD modeling and/or modeling of complex biological...Full timeSummer workRemote workFlexible hours2 days per week
$190k - $240k
...is seeking a highly motivated and detail-oriented Director specializing in immuno-oncology to join our Translational Medicine team in Cambridge, MA. This individual... ...validation, and execution of clinical biomarker and PK/PD assays with external CROs and actively manages...Flexible hours3 days per week- ...patients. Purpose of the Role: The Senior/Executive Director [commensurate with experience], ExploR&D Translational Medicine incumbent is responsible for the... ...doses, dose ranges and in interpreting emerging human PK/PD data to inform dose escalation and dose regimen selection...
$154.4k - $242.55k
...and empower you to shine? Join us as Associate Director, Quantitative Clinical Pharmacology Lead... ...and/or independently performs PK, PD, and pharmacometric analyses including... ...Scientific understanding of biological translation, drug development and its integration...Minimum wageTemporary workWork experience placementWork at officeLocal areaRemote work
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