Principal Investigator/Bioanalytical Lead Scientist I- (LC-MS)

Labcorp is a leader in diagnostics, drug development and healthcare innovation. Across every role, we harness data and AI to work smarter, move faster and create breakthrough solutions that improve health outcomes for people. With our global scale and deep expertise, you'll do meaningful work, grow your career and make a real impact. Together, we're improving health and improving lives.

Lead Scientist I & Principal Investigator to support our LC/MS Bioanalytical Study Team  in Madison, WI

Work Schedule - Mon-Fri (Day Shift)

Job Responsibilities :

• Leads and directs scientific work to support external methods and projects.

• Serves as an SD, RS, CS, LS, or PI for non-regulated, GLP-regulated, and GCP-regulated studies as applicable.

• Ensures client programs meet Labcorp, client, and regulatory requirements in order to meet defined milestones along the drug development pathway.

• Develops and reviews protocols and sample analysis plans.

• Reviews data with the Method Development Team to ensure methods are ready for validation.

• Approves validation methods and reviews sample analysis methods.

• Independently reviews and approves raw data.

• Ensures that any circumstances that may affect the quality and integrity of the study are identified and documented as the occur and appropriate corrective action is taken.

• Effectively evaluates data and tables to ensure regulatory guidelines and expectations are met.

• Reviews and approves reports for scientific accuracy and completeness.

• Ensures on-time delivery of high quality data and reports.

• Provides technical support as needed.

• Leads efforts to troubleshoot and solve assay problems.

• Recognizes the functions of different teams within Labcorp and seeks guidance when appropriate.

• Manages scientific investigations.

• Approves QA project specific inspections.

• Approves data archival.

• Evaluates new proposals for technical feasibility.

• Supports scientific papers or posters which are published or presented at scientific meetings.

• Serves as the scientific point of contact for the client.

• Effectively works with the client to determine project requirements.

• Leads preinitiation meetings when needed.

• Gives scientific directives to the study team.

• Identifies scientific issues or scope changes within the study.

• Communicates and monitors scientific expectations with scientific staff and clients.

• Proactively identifies ways to increase client satisfaction.

• Participates in client visits as a scientific lead.

• Responds to unscheduled deadlines, client needs, and crises without neglecting other responsibilities.

• Assists clients with experimental design outside the scope of SOPs.

• Develops and delivers compelling messages that connect with the audience.

• Promotes quality within the study team.

• Provides a technical resource for less experienced team members.

• Actively promotes collaboration within and across groups.

• Communicates successes and provides positive recognition to team members.

• Promotes a positive impression of Labcorp internally and within the industry.

• Provides technical and scientific guidance to clients and other departments.

• Leads new employee training and develops training materials and schedules.

• Identifies process improvement opportunities, participates in execution of initiatives.

• Advocates Labcorp ethics, vision, and values; fosters a high-performance culture.

• Participates in projects and tasks in addition to lead scientist responsibilities.

• Regularly provides support to other lead scientists or project managers.

• Mentors other employees.

• Able to plan, prioritize, and manage workload for large and complex projects.

• Demonstrated ability to manage high volume study work for key clients.

• Takes accountability and demonstrates responsibility regarding scientific study conduct.

• Good knowledge of client requirements.

• Manages time effectively.

• Performs other related duties as assigned.

Minimum Qualifications:

• Bachelors Degree (Chemistry, Biology)

• 3-4 years or more experience supporting lead scientific projects that support external methods and projects

• 2 years or more Good Laboratory Practice (GLP) experience required

• 2 years or more Liquid Chromatography Mass Spectrometry experience required

• 2 years or more Bioanalytical Method Development and Validation

Preferred Qualifications :

• Masters (MS) degree in science or related field preferred

• 1 year or more experience Watson, Nautilus, and Analyst software

• 1 year or more experience Root Cause Analysis

• 2 years or more experience working with regulatory agency guidelines and SOP's

Additional Job Standards:

• Excellent communication and interpersonal skills

• Proven ability to prioritize and manage time

• Excellent attention to detail

• Able to utilize word processing, database, spreadsheet, and specialized software

#LI-SD1

Application Window: 6/26 thru 7/26/2026

Pay Range: $80k – $95k annually

All job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data. 

Benefits: 

Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan. For more detailed information, please  click here .

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law. 

We encourage all to apply

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