Principal Software Engineer, Platform Engineering
$142.5k - $256.5kModerna Therapeutics
The Role:Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology, with a diverse pipeline of development programs across various diseases. Moderna is looking for a hands-on, impact-driven Principal Software Engineer, Platform Engineering to help define, build and evolve reusable platform capabilities that enable application teams to develop, deploy, and operate software safely and effectively. This is a senior individual contributor role that combines deep technical execution with cross-functional technical leadership across developers ("Builders"), Cybersecurity, Architecture, AI platform teams, and broader teams to provide scalable, secure, and user-focused capabilities that make the right path the easiest path for Moderna’s engineering teams. The initial focus for this role will be advancing AI runtime safety and AI gateway capabilities, including reusable integration patterns, policy enforcement, telemetry, secure development workflows, and operational tooling, and paved-road controls for governed AI assisted development. Over time, this role will influence and contribute across the broader Builder Tools & Platforms portfolio, including developer tooling, secure software delivery, internal frameworks, platform automation, and paved-road engineering standards. This role is well suited for a principal engineer who thrives in ambiguous, high-impact problem spaces and can move fluidly from strategy and architecture to hands-on implementation, cloud infrastructure, CI/CD, production operations, developer enablement, and secure software delivery. You will help translate emerging enterprise needs into reliable, reusable, and well-governed platform capabilities for Moderna’s engineering teams.Here’s What You’ll DoDesign and build secure platform capabilities using Python/TypeScript, GitHub Actions, Pulumi, Docker, AWS, and relevant internal or vendor APIs. Lead the design and evolution of AI runtime safety and AI gateway patterns, including policy enforcement, access controls, telemetry, auditability and operational controls. Build and guide implementation of governed AI-assisted development workflows by packaging approved tools, creating reusable integration patterns, improving developer experience, and embedding security and compliance expectations into paved-road delivery workflows. Partner with Cybersecurity, Architecture, AI platform teams, and engineering leaders to align on platform standards, adoption strategy, risk posture, and implementation tradeoffs. Create and drive adoption of templates, reference implementations, documentation, examples, and paved-road patterns that help application teams adopt secure development and AI-assisted workflows. Improve developer experience by identifying systemic friction, reducing setup time, eliminating manual toil, standardizing common workflows, and making secure patterns easy to adopt. Establish and mature operational practices for owned capabilities, including monitoring, alerting, dashboards, runbooks, support models, service ownership, and lifecycle management. Identify recurring developer pain points and influence roadmap by proposing improvements to shared frameworks, templates, platform tooling, and paved paths. Lead integration of secure software delivery controls into development workflows, including CI/CD guardrails, policy checks, artifact controls, and developer remediation patterns. Contribute hands-on across Builder Tools & Platforms priorities as team needs evolve, including developer tooling, platform automation, secure delivery patterns, internal frameworks, and operational support. Mentor and coach engineers, raise engineering standards, review design and implementations, and help teams make durable technical decisions across platform and applications boundaries Here’s What You’ll Need (Minimum Qualifications)10+ years of experience in software engineering, platform engineering, DevOps, infrastructure automation, secure software delivery, or a related role. Deep software engineering experience designing, implementing, and operating developer platforms, internal tools, infrastructure automation, CI/CD systems, or secure software delivery platforms. Very strong programming skills in Python or TypeScript/JavaScript. Significant experience with GitHub, GitHub Actions, CI/CD workflows, and modern software delivery practices. Significant experience with AWS or another cloud provider for deploying and managing applications or platform services. Experience with Docker and containerized applications. Strong understanding of secure software development practices, software supply chain, dependency management, vulnerability scanning, artifact management, secrets handling, identity, authorization, and policy enforcement. Proven ability to set technical direction and design systems that balance security, standardization, usability, reliability, and developer productivity. Proven experience leading technical initiatives with cross-functional stakeholders. Demonstrated ability to mentor engineers, raise technical standards, and guide teams through architecture, design, implementation, and operational tradeoffs. Expert troubleshooting skills across application code, build pipelines, cloud infrastructure, networking, identity, developer tooling, and third-party platforms. Demonstrated ability to adapt to changing team priorities, operate effectively in ambiguous problem spaces, and contribute across a range of platform engineering responsibilities, including areas outside immediate prior experience. Here’s What You’ll Bring to the Table (Preferred Qualifications)Experience with AI-assisted development tooling, AI gateway patterns, model or API access controls, policy-as-code, telemetry, or runtime safety controls. Experience shaping platform strategy or technical roadmaps for capabilities adopted by multiple engineering teams. Experience partnering with security, architecture, platform, and application teams to drive adoption of shared capabilities and standards. Experience with infrastructure-as-code tools such as Pulumi, CDK, Terraform, or similar. Experience with application security, cloud security, software supply chain controls, vulnerability management workflows, or secure CI/CD guardrails. Experience building internal developer platforms, paved-road workflows, reusable templates, CLIs, scaffolding systems, or shared engineering standards. Experience with Kubernetes, container security, base image lifecycle management, secrets management, network isolation, or secure runtime patterns. Experience creating documentation, reference architecture, onboarding materials, and developer enablement content for shared platform capabilities. Pay & BenefitsAt Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.Competitive healthcare, plus voluntary benefit programs to support your unique needsA holistic approach to well-being, with access to fitness, mindfulness, and mental health supportFamily planning benefits, including fertility, adoption, and surrogacy supportGenerous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdownSavings and investments to help you plan for the futureLocation-specific perks and extrasThe salary range for this role is $142,500.00 - $256,500.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Our Working Model As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal OpportunitiesModerna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. AccommodationsWe’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at View email address on click.appcast.io. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #LI-CK1-SummaryLocation: Cambridge, Massachusetts; DigitalType: Full time
- ...requiredSECRET Security Clearance Required; TS+ clearance preferred5+ years of experience as a Software EngineerExperience with distributed system architectures, secure platform engineering, and knowledge graphsStrong programming skills in Python, expertise in React and...SuggestedApprenticeshipEasy work
$188k - $257.5k
...Flagship Pioneering is building intelligent software systems that integrate agentic AI... ...effort is a new autonomous research platform. It supports autonomous AI systems... ...biological problems. We are seeking a Principal Software Engineer to own the underlying agentic platform...Suggested$168.6k - $224.8k
...Tools and Automation organization, the Test Platform Services (TPS) team builds and operates... ...hardware, firmware, and distributed software systems to ensure our devices behave correctly... ...production.We are seeking a Software Engineer to lead TPS’s technical vision while...SuggestedWork at officeShift work$188k - $257.5k
...Principal Software Engineer - Agentic Platform Cambridge, MA USA The Role The Pioneering Intelligence group at Flagship Pioneering is building intelligent software systems that integrate agentic AI with scientific reasoning to accelerate discovery and decision...Suggested$250.6k - $362.6k
...will join Cisco’s Security and Policy Platform Group, a foundational organization responsible... ...comprehensive security outcomes, as a Principal Engineer. The team delivers secure, scalable... ..., develop, and drive unique software and technology solutions with global impact...SuggestedFull timeTemporary workLocal areaRemote workFlexible hours$266.2k - $425.9k
...Acceleration group empowers over 2,000 engineers to build, test, and deploy... ...for rethinking how software gets shipped at scale — and what... ...the RoleWe're looking for a Principal Software Engineer to help define... ...of HubSpot's delivery platform should look like — not just how...Live outWork at officeRemote workShift work- ...ecosystem that delivers accessible, high-quality, and sustainable healthcare for all.Role Summary Join our innovative team as a Principal Software Engineer in Boston, MA, where you will play a pivotal role in shaping the future of medication management. This hybrid position...Full timeTemporary workWork at office
$114.2k - $267.8k
...carriers and the customers they serve. We build AI-powered software that keeps everyone in the claims conversation informed... ...a human touch, we’d love to meet you. We're looking for a Principal Software Engineer, a person trusted with our hardest, highest-leverage technical...Flexible hours2 days per week3 days per week$88k - $168k
DescriptionDo you bring deep full-stack software engineering experience and the judgment to... ...performance and cost efficiency of a cloud platform?If this sounds like you and you are driven... ...by purpose, join SOPHiA GENETICS as a Principal Software Engineer and enable us to...Full timeContract workTemporary workWork at officeLocal areaWork from homeWorldwideWeekend work$266.2k - $425.9k
...clarity, and predictability matter.We're building a commerce platform where the data model, APIs, and flows are first-class.... ...risk before it's too late.About the RoleWe're looking for a Principal Software Engineer to help shape the technical future of Revenue Hub. This is...Contract workLive outWork at officeRemote work$108k - $209k
...psychological fitness and wellbeing. We are creating a platform that empowers people to build a life they are proud of and... ...We are seeking an experienced, creative, and talented Principal / Senior Software Engineer. The ideal candidate will have a strong background in software...$131k - $200k
...transforming, and PTC is leading the way. Our software brings the physical and digital... ...we are and the work we do possible. Principal Software Engineer (SRE)-Onshape Hybrid-Boston, MAAbout... ..., and operational excellence of our platform.As a Principal Software Engineer, you...Permanent employmentFull timeWork at officeLocal areaImmediate startVisa sponsorshipFlexible hours$244k - $366k
...their own destiny.Be Klaviyo’s senior IC for scale, you will report into a VP of Engineering and lead performance, reliability, multi‑region, and large‑tenant readiness. You’ll drive platform-wide architectural change, hunt bottlenecks and optimize systems, and partner...$147k - $237.5k
...United States* We’re looking for a Principal Escalation Engineer to serve as a key architect of customer... ...~8+ years of experience in the software industry (Technical Support, R&D, or... ...of CyberArk’s next-generation cloud platform. Compensation Disclosure The compensation...Full timeWork at officeImmediate startShift work$107.5k - $204.5k
...Security Clearance Status: Not RequiredOur Connected Aviation - Air Traffic Solutions - Software Engineering Department (ATS-SED) is looking for a talented experienced Principal Software Engineer to join our team developing and supporting our Air Traffic Control Systems...Contract workTemporary workWork experience placementStart working todayWork at officeRemote workWorldwideFlexible hours$150k - $210k
...maintenance of all three packages, and we're hiring an experienced engineer to serve as a primary maintainer. You'll take broad ownership... ..., community-facing disposition. Substantial professional software engineering experience building and maintaining production-grade...Full timeWork at officeLocal areaImmediate startFlexible hours$150k - $180k
...professional to join its Enterprise Solutions (ES) team as a Principal Software Engineer based in Boston. This role offers a unique opportunity to... ..., accessible, and user-friendly interfaces across platforms.Design and fine-tune database architectures with a focus on...Temporary workFlexible hours- ...that provide peace of mind for our customers worldwide. As a principal software engineer at Liberty Mutual, you’ll consult on highly complex... ...Workflow & Automation squad powers Bridgeway, our Micro Frontend platform that enables rapid, scalable React application development...Work at officeLocal areaWorldwide
$107.5k - $204.5k
...AerospaceCollins Aerospace, an RTX company, is a leader in engineering and proposal teams to successfully execute... ...to work at RTX.The Strategic Communication Software (SW) Engineering Department has an opportunity for a talented Principal Software Engineer to join our team. What You...Temporary workWork experience placementWork at officeRemote workFlexible hours$107.5k - $204.5k
...than 100 years of experience and renowned engineering expertise to meet the needs of today’s... ...and defense.We are seeking Senior Software Engineers to join our development team... ...support multiple programs and multiple platforms within a software product line. Software...Temporary workWork experience placementInterim roleWork at officeLocal areaRemote workRelocationFlexible hours$150k - $300k
...impact on its customers, employees, and communities.The RoleAs Principal Software Engineer for a new product within Veeva, you will be a founding member of a team building our next major AI-driven platform — one that will transform how Life Sciences companies manage safety...Work at officeLocal areaRemote workWork from homeFlexible hours3 days per week- Senior, Principal or Lead Software Engineer, Artificial Intelligence, fully remote, 145k to 195k base, bonusCompensation Commensurate with experience... ...development and deployment of AI-based products and platforms.Responsibilities Duties involve leading, designing and developing...Permanent employmentH1bRemote workVisa sponsorship
- ...Principal Software EngineerThis role will require a 4-day hybrid work schedule in one of our primary... ...not an option.The Principal Software Engineer serves as a technical authority and... ..., Kubernetes, and/or OpenShift.Cloud platform experience with AWS, Microsoft Azure,...Local areaRemote workFlexible hours
- ...Principal Software EngineerLocation: Boston, MA; NC; Salt Lake City, UT; Smithfield, RI/RemoteDuration: Long TermRequired Skills: Java, J2EE, Spring Boot, REST, Microservices, API developmentPreferred Skills: Kafka, UI, Spark, Docker, React, Kubernetes, Angular8+, AWSMust...
$135.2k - $306.4k
...to real-world cloud-scale distributed systems, as part of an engineering organization that highly values formal methods. OCI has been using... ...and verification. ~5+ years of full-time professional software development of concurrent and distributed systems, ideally cloud...Full timeTemporary workFlexible hours- ...Principal Software Engineer We're looking for a Principal Software Engineer to join the world-class team combining two of the top private sale e-commerce destinations. This is an opportunity to be directly involved in scaling our systems towards $1B annual sales using...
$152k - $228.5k
...Principal Software EngineerWith 1,000+ intelligence professionals serving over 1,900 clients worldwide... ...is seeking a Principal Software Engineer to join our Engineering team,... ...architectural improvements and ensuring the platform scales effectively as it continues to...Full timeWorldwide- ...Principal Software Engineer Duration: Long term Contract Location: Boston, MA (onsite) Must have skills: Python AND Financial Systems Knowledge of financial systems Solid understanding of statistics and how it plays with...Long term contract
- ...Principal Software Engineer Location: Boston MA, Remote till covid Duration: 12+ months Job Description: Bachelor level degree in... ...programming languages, frameworks, operating systems, and platforms Strong technical design skills and experience with object...Remote work
- ...JOB MISSION: New Balance is seeking an experienced Principal Software Engineer to join our Enterprise AI Solutions team. This team is responsible... ...work closely with cross-functional partners, data and platform teams, and other engineers to design, implement, and...Temporary workPart timeWork at officeFlexible hours3 days per week
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Software Engineer, Platform Engineering. Be the first to apply!
- principal software engineer Cambridge, MA
- senior platform engineer Cambridge, MA
- platform developer Cambridge, MA
- platform engineer Cambridge, MA
- principal applied scientist Cambridge, MA
- senior principal scientist Cambridge, MA
- principal scientist Cambridge, MA
- senior principal cloud computing engineer Cambridge, MA
- principal Cambridge, MA
- software support Cambridge, MA


