Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior PK/PD Scientist - RNAi Therapeutics & Modeling

$140.3k - $189.7k

Alnylam Pharmaceuticals

Alnylam Pharmaceuticals in Cambridge, MA is seeking a Sr. Scientist in Clinical Pharmacology to support an expanding clinical portfolio of RNAi therapeutics. The ideal candidate will possess strong expertise in pharmacokinetics and pharmacodynamics, with experience in data analysis and visualization skills using tools such as R and Phoenix. Responsibilities include leading analyses, providing regulatory input, and collaborating closely with various project teams. This role offers a competitive salary range of $140,300 - $189,700, and is eligible for both short-term and long-term incentive awards. Alnylam offers a robust Total Rewards package including comprehensive health benefits, paid time off, wellness days, and other family resources. #J-18808-Ljbffr Alnylam Pharmaceuticals

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Senior PK/PD Scientist - RNAi Therapeutics & Modeling in Cambridge, MA vacancy
  • Vertex Pharmaceuticals is seeking a Modeling & Simulations Scientist II to lead high-quality PK/PD programming and manage programming deliverables for studies. The role involves ensuring quality in datasets, developing automated solutions, and guiding a team of programmers... 
    Suggested
    Remote job
    Flexible hours

    Vertex Pharmaceuticals

    Boston, MA
    1 day ago
  • $190.8k - $300.3k

     ...Scientific Director for the Translational PK/PD organization in Boston, MA. The role...  ...physiologically-based pharmacokinetic (PBPK) modeling and leadership in drug discovery....  ...guiding modeling strategies, mentoring scientists, and collaborating across teams. Ideal candidates... 
    Senior

    MSD Malaysia

    Boston, MA
    4 days ago
  • $177k - $308k

     ...biotech companies access to drug discovery models trained on years of Lilly's research data...  ...predictive models across key ADMET and PK/PD endpoints — including clearance, permeability...  ...Mentorship: Provide coaching to junior scientists and contribute to TuneLab's growing ADMET... 
    Senior
    Full time
    Flexible hours

    Eli Lilly and Company

    Boston, MA
    1 day ago
  •  ...leading biopharma company in Cambridge, MA seeks a Senior Scientist to lead the development of advanced ocular in vitro models. You will apply your expertise in iPSC...  ...chance to make a lasting impact on ophthalmology therapeutics and develop vision-preserving treatments... 
    Senior

    Sanofi

    Cambridge, MA
    1 day ago
  • $150k - $190k

     ...are seeking a highly skilled computational protein scientist to execute complex protein design and modeling work across our portfolio. Working closely with...  ...hands‑on with existing portfolio companies on active therapeutic programs, while also contributing to the formation... 
    Senior

    TryApplyNow

    Boston, MA
    17 hours ago
  • $100.5k - $145.17k

    **Job Title:** Senior Scientist, Advanced Ocular In Vitro Models**Location:** Cambridge, MA**About the Job**Join the engine of Sanofi’s mission — where deep...  ...while driving innovation in disease modeling and therapeutic evaluation. This position offers the opportunity to... 
    Senior
    Worldwide

    Sanofi

    Cambridge, MA
    1 day ago
  • Initial Therapeutics, Inc. is seeking a Senior Scientist in Automation and Advanced Modeling in Cambridge, MA. In this role, you will develop automated laboratory systems and support modeling solutions for drug substance development. The ideal candidate will have a PhD... 
    Senior

    Initial Therapeutics, Inc.

    Cambridge, MA
    2 days ago
  • $108.5k - $201.5k

     ...enthusiastic and motivated PK Sciences project team...  ...molecules, biologics/therapeutic proteins, antibody drug...  ...Disposition (ADME, BA), Modeling & Simulation (M&S), and...  ...understanding of PK/PD relationships and develop...  ...considered for Principal Scientist II •    Extensive and... 

    Research

    Cambridge, MA
    more than 2 months ago
  • $146k - $209k

    Vesalius Therapeutics is seeking a computational biologist with 5+ years of experience in high...  ...development, mentoring junior data scientists and advising stem cell scientists and biologists...  ..., and iPSC-based physiological models and champion decisions and next steps... 
    Senior

    Flagship Pioneering

    Cambridge, MA
    1 day ago
  • $140.3k - $189.7k

    Overview The Sr. Scientist in Clinical Pharmacology position will...  ...portfolio of promising RNAi therapeutics. The candidate in this position...  ...should be well versed in PK and PD with strong ability to critically...  ...analysis, and PKPD modeling. In this role, the candidate... 
    Senior
    Full time
    Temporary work
    Local area
    Flexible hours

    Alnylam Pharmaceuticals

    Cambridge, MA
    1 day ago
  • $150k - $200k

     ...an experienced and versatile Senior Scientist, Computational Biology to...  ...support for our oligonucleotide therapeutics pipeline. This is a hands‑on...  ...activity in preclinical models. Design, execute, and interpret...  ...programs, including PK/PD characterization and biomarker... 
    Senior
    For contractors
    Flexible hours

    Orro

    Cambridge, MA
    17 hours ago
  • $100.5k - $145.17k

    Job title: Senior Scientist, Advanced Ocular In Vitro Models Location: Cambridge, MA About the Job Are you ready to shape the future of ophthalmology research...  ...while driving innovation in disease modeling and therapeutic evaluation. This position offers the opportunity to... 
    Senior
    Full time
    Worldwide

    Sanofi

    Cambridge, MA
    1 day ago
  •  ...and scientifically rigorous Scientist/Senior Scientist with deep expertise...  ...relevant kidney disease models to build and lead our kidney...  ...discovery, mechanistic validation, therapeutic screening, and development...  ...knockdown. In vivo PK/PD, biodistribution, efficacy,... 
    Senior

    Initial Therapeutics, Inc.

    Boston, MA
    2 days ago
  • MSD Malaysia is seeking a Senior Scientist for Biomarker Discovery based in Cambridge, MA. This role involves designing and optimizing immunological...  ...candidate diagnostics development using advanced cellular models. Ideal candidates will have extensive experience isolating... 
    Senior

    MSD Malaysia

    Cambridge, MA
    2 days ago
  • A leading biotechnology R&D center in Cambridge, Massachusetts is seeking a Senior Scientist to develop 3D skin tissue models. This role demands expertise in anti-aging research and collaboration within bioengineering teams. The ideal candidate will have a PhD/MS in Bioengineering... 
    Senior

    Oddity Labs, Llc.

    Cambridge, MA
    2 days ago
  • A pioneering venture firm based in Cambridge seeks a Machine Learning Engineer to develop innovative ML models for complex measurement data. The successful candidate will have a strong background in Python and modern ML frameworks, particularly with hands-on experience... 
    Senior

    Flagship Pioneering

    Cambridge, MA
    3 days ago
  • A leading biopharma company in Cambridge, MA is seeking a Senior Scientist in Automation and Advanced Modeling to enhance laboratory processes through automation and modeling techniques. The ideal candidate will have a PhD or equivalent in relevant fields, strong programming... 
    Senior

    Sanofi

    Cambridge, MA
    1 day ago
  • $126.4k - $189.6k

     ...of individuals, driving discoveries that directly inform our RNAi therapeutics pipeline. In this role, you will champion methodological...  ...emerging approaches (e.g., multi‑omics integration, polygenic modelling, rare variant aggregation, AI/ML‑enabled prioritisation). Help... 
    Senior
    Full time
    Temporary work
    Local area
    Flexible hours

    Alnylam Pharmaceuticals

    Cambridge, MA
    3 days ago
  • **Job title**: *Senior Scientist Automation and Advanced Modeling** *Location: Cambridge, MA***About the Job** We are seeking highly motivated individual to join our drug substance process engineering and modeling team. As a technical expert in process engineering and modeling... 
    Senior
    Work experience placement

    Sanofi

    Cambridge, MA
    1 day ago
  • $128.6k - $210k

    Regeneron Pharmaceuticals, Inc is seeking a Senior Clinical Pharmacologist to lead the planning and analysis of pharmacokinetic studies. The ideal candidate will hold a PhD in relevant fields and have at least 3 years of clinical pharmacology experience. This role involves... 
    Senior

    Regeneron Pharmaceuticals, Inc

    Cambridge, MA
    4 days ago
  • $124.6k - $187k

    **Job Description****General Summary:**The Modeling & Simulations Scientist II-(PKPD Programming) is a primarily hands-on programming leader responsible for delivering high-quality PK/PD, PopPK, and exposure-response analysis datasets, outputs, and regulatory submission... 
    Summer work
    Work at office
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    1 day ago
  • $146k - $209k

    Senior Scientist, Computational Genomics Cambridge, MA USA Company Summary We are building a...  ...MRNA), Generate Biomedicines, Tessera Therapeutics, and Quotient Therapeutics. We are an...  ...statistical genetics and statistical modeling. The role includes responsibility of the... 
    Senior

    Flagship Pioneering

    Cambridge, MA
    17 hours ago
  • $220k - $270k

    Principal or Senior Principal Scientist, Protein Drug Discovery page is loaded## Principal or Senior...  ...Provide scientific leadership across therapeutic protein modalities (e.g., antibodies...  ...to interpret and apply computational modeling/design insights in experimental decision... 
    Senior

    Zealand Pharma group

    Cambridge, MA
    3 days ago
  • Senior Scientist/Principal Scientist, Bioinformatics, within the Data Science team. The role involves...  ..., signalling pathways, biomarkers, and therapeutic modalities. Experience with single‑...  ..., knowledge graphs, large language models, or foundation models, to biological data... 
    Senior
    Local area

    Integratedcooling

    Watertown, MA
    2 days ago
  • $163.5k - $281.6k

     ...medicines. Job Summary We are looking for an RNAi drug discovery expert with deep...  ...opportunities, design and execution of novel RNAi therapeutics within ExploR&D, and partnership with...  ...selection, human-relevant pharmacology models, purification and formulation best... 
    Full time
    Flexible hours

    Eli Lilly and Company

    Boston, MA
    3 days ago
  •  ...company is seeking a skilled cheminformatics scientist to join its team in Boston. The ideal...  ...designing workflows and predictive models, collaborating closely with global teams...  ...Competitive compensation and benefits are offered. #J-18808-Ljbffr Initial Therapeutics, Inc.
    Senior

    Initial Therapeutics, Inc.

    Boston, MA
    4 days ago
  • Senior Scientist Immunology (Boston, MA) As a Senior Scientist Immunology overseeing the design and...  .... Establish and validate in vitro models of autoimmune diseases; support the design...  ...execution of in vivo experiments such as PK, tox, dosing. Develop and perform biochemical... 
    Senior

    CeDent

    Boston, MA
    1 day ago
  •  ...transformative precision allosteric therapeutics to address serious unmet...  ...: We are seeking a Senior Scientist, DMPK, to join our R&D...  .... Propose ADME/PK, biodistribution and PK-PD approaches at team discussions...  ...to optimize preclinical models and inform on first in human... 
    Senior
    Flexible hours

    Atavistik Bio

    Cambridge, MA
    22 days ago
  • $100k - $140k

    Overview We are seeking an accomplished Senior Scientist to join a leading global pharmaceutical...  ...and drive the validation of novel therapeutic targets in complex disease areas. The successful...  ...relevant in vitro, in vivo, or ex vivo models. Excellent communication skills, with... 
    Senior
    Full time
    Relocation package

    Sphere Recruitment

    Cambridge, MA
    2 days ago
  • $270k - $295k

    A growing biotech firm in Cambridge is seeking a Senior Director, DMPK to lead DMPK strategy, manage regulatory submissions, and guide...  ...roles, a Ph.D. in a relevant field, and expertise in oncology therapeutic programs. The firm offers a competitive salary range of $270,0... 
    Senior

    Nuvalent, Inc.

    Cambridge, MA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior PK/PD Scientist - RNAi Therapeutics & Modeling. Be the first to apply!