Senior Research Associate V - Protein Development

Job Description

Job Description

1. Understanding the actual requirement

This is a highly specialized Protein Analytical Development / Assay Development position.

The client needs an experienced scientist who can independently perform protein quantification and quality assessment for cell-free protein synthesis (CFPS) raw materials and in-process intermediates.

The person will primarily own two analytical methods:

1. Sandwich ELISA – specifically for RNA synthetase and RNA polymerase lysates.
2. Bradford protein assay – for total protein quantification.

The candidate will also support assay qualification, reagent qualification, troubleshooting, data analysis, and automation of high-throughput assays.

This is not a general protein research or molecular biology position.

The strongest candidate is someone with extensive hands-on ELISA and Bradford assay experience, preferably in pharmaceutical or biotechnology analytical development, with exposure to method qualification and laboratory automation.

2. Must-have technical skills

Priority

Technical skill

What recruiters should validate

Critical

Sandwich ELISA

Independent assay execution

Critical

Bradford assay

Total protein quantification

Critical

Protein analytical methods

Protein concentration and quality

Critical

Method qualification

Accuracy, repeatability, precision

High

Reagent qualification

Antibodies, standards, assay controls

High

Benchling

Electronic laboratory records

High

Data analysis

Assay variability and interpretation

Preferred

GFP activity assay

Protein activity measurement

Preferred

Capillary Western

Jess / Leo

Preferred

A280 / SoloVPE

Protein concentration measurement

Preferred

Tecan EVO

Automated ELISA

Preferred

Biomek

Automated liquid handling

Important technical terminology

Recruiters should understand these terms:

• ELISA: Enzyme-linked immunosorbent assay used to quantify specific proteins.
• Bradford assay: Colorimetric method used to measure total protein concentration.
• CFPS: Cell-free protein synthesis, a system that produces proteins without using intact living cells.
• Jess / Leo: Automated capillary Western systems used for protein analysis.
• SoloVPE: Instrumentation used for protein concentration measurement.
• Tecan EVO: Automated liquid-handling platform used for laboratory workflows.

3. Ideal candidate backgrounds

Search for candidates with these job titles:

1. Senior Research Associate – Analytical Development
2. Senior Associate Scientist – Protein Analytics
3. Senior Scientist – Assay Development
4. Scientist – Protein Characterization
5. Senior Research Associate – Biochemistry
6. Analytical Development Scientist – ELISA
7. Senior Scientist – Protein Quantification
8. Associate Director / Principal Associate – Analytical Sciences (only if hands-on and rate-aligned)

** Our Company offers a very competitive benefits program including paid time off, medical, dental, vision, and a 401K.

Company Description

Founded in 2015 and backed by two decades of hands-on experience, our strong insight on the enterprise ecosystem and its dynamics helps to offer a complete end-to-end solution. We automate recruitment processes with intelligent solutions to save time and money. Synkriom leads the industry with experience authentication of candidates.

Company Description

Founded in 2015 and backed by two decades of hands-on experience, our strong insight on the enterprise ecosystem and its dynamics helps to offer a complete end-to-end solution. We automate recruitment processes with intelligent solutions to save time and money. Synkriom leads the industry with experience authentication of candidates.