Assoc Director/Director, IT

Are you ready to join a team committed to making a meaningful impact on cancer treatment through the discovery and development of precision medicines? At Kura Oncology, you have an opportunity to be a part of something bigger, with a lasting impact that you can be proud of.

At Kura Oncology, we are working to change the paradigm and improve the science of cancer treatment. As an organization, we strive to cultivate a diverse and talented professional culture driven to develop precision medicine therapeutics.

As we continue to build a leading biotech organization with a strong culture, a patient-focused mindset and a team focused on relentless execution, we are looking for innovative, passionate professionals to join us and make our vision a reality.

To succeed at Kura, you will need to have a demonstrated ability for excellence in drug discovery and development and a roll-up your sleeves attitude. The ideal candidate will possess a values-driven work style where integrity and grit drive all behaviors, decisions, and actions.

ESSENTIAL JOB FUNCTIONS:

We are seeking an experienced and visionary leader to join our IT leadership team as the Associate Director/Director of IT. This pivotal role reporting to the Head of IT, will be responsible for shaping and executing our IT strategy, managing our IT portfolio, driving change management initiatives, leading IT communications, refining our IT operating model, co-managing IT budget and forecasting and supporting business system owners (BSO’s) in new compliance initiatives

IT Strategy and Portfolio Management

• Develop, implement, and continuously refine a comprehensive IT strategy in partnership with the Head of IT and functional stakeholders that aligns with and supports overall business objectives.
• Drive innovation by integrating emerging technologies and leading digital transformation initiatives that align with the strategic vision of Kura Oncology.
• Establish and maintain a robust IT portfolio management framework, including tools and processes for project prioritization, resource allocation, and performance tracking.
• Conduct regular portfolio reviews to ensure optimal balance of risk, value, and strategic alignment.
• Collaborate with business units and system owners to identify and prioritize IT initiatives that drive business value.
• Implement and maintain security policies based on roadmap initiatives and business goals of the company.
• Evaluate system vulnerabilities and conduct regular audits, risk assessments, and compliance checks to ensure security standards are met.
• Coordinate with the Incident response team in responding to any security incidents and investigating root causes, while implementing corrective measures to prevent future occurrences.

AI Strategy, Governance, and Enablement

• Partner with the Head of IT and business leaders to develop and execute the company’s enterprise AI strategy and roadmap, identifying opportunities to leverage artificial intelligence, generative AI, and automation to improve productivity, decision making, and business outcomes.
• Establish and maintain an AI governance framework addressing appropriate use, data privacy, information security, regulatory compliance, intellectual property, risk management, and responsible AI practices.
• Lead the evaluation, selection, and implementation of enterprise AI platforms, tools, and capabilities, ensuring alignment with the company’s technology architecture, security requirements, and business objectives.
• Partner with functional stakeholders to identify, prioritize, and develop high value AI use cases across the organization, establishing clear business outcomes, ownership, success criteria, and measures of value.
• Collaborate with Information Security, Legal, Compliance, Quality, and business stakeholders to assess and manage risks associated with AI technologies, including sensitive and confidential data, model outputs, third party services, and regulatory requirements.
• Develop policies, standards, and procedures governing the responsible use of generative AI and other AI technologies across the organization.
• Drive responsible adoption of AI through employee education, training, communications, and change management programs that improve AI literacy and encourage effective and appropriate use of approved AI tools.
• Ensure AI solutions supporting GxP or other regulated business processes are appropriately assessed, documented, validated, and governed in partnership with Quality and applicable Business System Owners.

Change Management and Communications

• Develop and execute comprehensive change management strategies for major IT initiatives and organizational transformations.
• Create and maintain a change management framework and train IT Team on effective use to deliver change in a consistent manner.
• Lead the development and execution of multi-channel IT communication plans, ensuring clear and effective messaging to all stakeholders.
• Establish feedback mechanisms to measure the effectiveness of change initiatives and communications.
• Collaborate with HR and other departments to align IT changes with broader organizational change efforts.

Compliance & Validation Management

• Ensure IT systems used in GxP-regulated processes and implemented, validated, and maintained according to regulatory standards and Kura business processes.
• Collaborate with Business Systems Owners, IT, and Quality teams to develop and execute validation deliverables (IQ/OQ/PQ).
• Monitor system changes to ensure compliance with change control procedures and regulatory standards

GxP System Audits and Inspections

• Support internal and external audits, including those conducted by regulatory authorities (e.g., FDA, EMA).
• Prepare compliance documentation and provide necessary evidence for GxP audits and inspections.
• Follow up on audit findings and assist with remediation plans to close gaps

IT Operating Model and Governance

• Continuously assess and refine the IT operating model to enhance efficiency, effectiveness, and alignment with business needs.
• Establish and maintain IT governance frameworks, including decision-making processes to support cross functional steering committees and drive efficiencies across IT.
• Develop and oversee IT performance metrics and scorecards to drive continuous improvement.

Budget and Forecasting

• Working with Head of IT to oversee the development and management of the annual IT budget, ensuring alignment with strategic priorities and maximizing ROI on IT investments.
• Implement robust financial management processes that can be quickly adopted/adapted to by the IT Team.
• Develop accurate IT financial forecasts, considering technology trends and business growth projections.

JOB SPECIFICATIONS:

• Bachelor’s degree in a related technical or business discipline required.
• A minimum of 8-10 years of progressive experience in IT leadership roles, with at least 5 years in management positions
• Proven track record in developing and implementing enterprise-wide IT strategies that drive business value
• Understanding of current security practices and standards for mid-size enterprise IT
• Extensive experience in portfolio management, including the use of portfolio management tools and methodologies
• Strong background in change management, with demonstrated success in managing complex organizational changes
• Expertise in IT financial management, including budgeting, forecasting, and cost optimization techniques, SOX reporting
• In-depth knowledge of IT governance frameworks (e.g., COBIT, ITIL) and experience implementing governance structures
• Proven ability to communicate effectively with C-level executives, board members, and diverse stakeholder groups
• Strong analytical skills with the ability to translate complex technical concepts into business terms
• Experience with digital transformation initiatives and emerging technologies (e.g., cloud, AI, IoT)
• Track record of building and leading high-performing teams in a fast-paced, dynamic environment
• Strong negotiation skills and experience managing vendor relationships and contracts
• Demonstrated commitment to continuous learning and staying current with industry trends and best practices
• Makes decisions for assigned programs or functional areas, balancing priorities and resolving routine challenges; escalates high-impact or cross-functional decisions as needed.
• Facilitates cross-functional coordination for assigned programs or initiatives, ensuring alignment and timely execution of deliverables.

The base range for this role at the Associate Director level is $186,000 - $218,000 and Director level is $221,000 - $259,000. Individual pay may vary based on additional factors, including, and without limitation, job-related skills, experience, work location, and relevant education or training. Kura's compensation package also includes generous benefits, equity, and participation in an annual target bonus.

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Kura’s Values that are used for candidate selection and performance assessments:

• We work as one for patients
• We are goal-focused and deliver with excellence
• We are science-driven courageous innovators
• We strive to bring out the best in each other and ourselves

The Kura Package

• Career advancement/ development opportunities
• Competitive comp package
• Bonus
• 401K + Employer contributions
• Generous stock options
• ESPP Plan
• 20 days of PTO to start
• 18 Holidays (Including Summer & Winter Break)
• Generous Benefits Package with a variety of plans available with a substantial employer match
• Paid Paternity/Maternity Leave
• In-Office Catered lunches
• Home Office Setup
• Lifestyle Spending Stipend
• Commuter Stipend (Boston Office)
• Regular employee social activities, including happy hours, monthly birthday celebrations, Kura Koffee Talks, and much more!

Kura Oncology is a commercial-stage biopharmaceutical company committed to discovering and developing innovative precision medicines to help patients with cancer lead better, longer lives.

Through our deep understanding of cancer biology and decades of experience in precision oncology, we are studying the underlying causes of treatment resistance. This enables us to design smart combination regimens with other cancer therapies to target tumors from multiple directions, with the goal of improving long-term clinical benefit.

Kura developed and is commercializing KOMZIFTI® (ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory NPM1-mutated acute myeloid leukemia, and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. For additional information, please visit Kura’s website at and follow us on X and LinkedIn.

Kura Oncology is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

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