Senior Director, Clinical Pharmacology

BridgeBio Pharma seeks a Senior Director of Clinical Pharmacology to lead pharmacology and pharmacometrics strategies across clinical development programs. The role involves overseeing population PK modeling, exposure-response analyses, regulatory submissions, and CRO management for small molecule development.

Responsibilities

• Develop and execute clinical pharmacology strategies across all development stages including pediatric programs
• Design, manage, and oversee population PK, exposure-response, PK/PD, and PBPK modeling analyses
• Author clinical pharmacology sections of regulatory submissions and support agency interactions
• Oversee clinical pharmacology study design, execution, and CRO management with protocol and report approval authority
• Present findings to internal teams and external stakeholders via publications and conference presentations

Requirements

• Ph.D. or Pharm.D. in Clinical Pharmacology, Pharmaceutical Sciences, or related field
• 10+ years of experience in biotechnology or pharmaceutical industry
• Demonstrated expertise in population PK, PK/PD, and mechanistic modeling
• Track record with quantitative data analysis and PBPK approaches
• Experience authoring regulatory documents and interacting with health authorities
• Ability to manage external CROs and cross-functional teams