Senior Principal Engineer, Agentic AI Platform, BYO Capability
$188k - $282kVertex Pharmaceuticals
Job DescriptionPosition SummaryVertex is seeking a Sr. Principal AI Engineer, Agentic AI Platform to design, build, and optimize the shared platform capabilities that power AI-enabled products and intelligent workflows across the enterprise. This role will focus on delivering production-grade platform services for model integration, prompt and workflow orchestration, evaluation, observability, performance optimization, and agent lifecycle management.A key focus of this role will be enabling a build/bring-your-own-agents capability within the Agentic AI Platform, allowing teams across Vertex to create, integrate, customize, and operationalize their own agents using shared platform standards, tooling, and governance controls.The ideal candidate combines strong software engineering fundamentals with deep experience in applied AI systems. This individual will be comfortable operating across rapid experimentation and engineering rigor, translating emerging AI capabilities into scalable, reliable, secure, and reusable platform components. The Senior Principal AI Engineer will play a critical leadership role in accelerating AI adoption across Vertex by enabling product teams to build and deploy AI solutions faster and more effectively.Key ResponsibilitiesArchitect and develop shared AI/agentic platform services that support enterprise AI products and internal workflowsDesign and implement a build/bring-your-own-agents capability that enables teams to create, register, integrate, deploy, and manage their own agents within the enterprise agentic platformEstablish reusable frameworks, SDKs, templates, interfaces, and guardrails that standardize how custom agents are built and onboarded onto the platformDefine agent lifecycle capabilities including agent registration, configuration, testing, deployment, monitoring, versioning, and retirementBuild and maintain robust integrations with foundation models, model gateways, APIs, enterprise tools, and related AI infrastructureDesign and implement systems for prompt orchestration, workflow execution, tool use, memory patterns, and agentic task coordinationDevelop reusable frameworks and services for evaluation, benchmarking, and validation of AI model, agent, and workflow performanceEstablish platform capabilities for observability, monitoring, tracing, logging, and alerting across AI workloads and autonomous agent interactionsOptimize platform performance, scalability, latency, reliability, and cost efficiency for production AI and agentic systemsPartner with product, data, engineering, security, and architecture teams to enable enterprise-ready AI solutionsTranslate prototypes and experimental concepts into hardened, maintainable, production-grade servicesDefine engineering standards, best practices, and design patterns for AI platform development and deploymentSupport governance, risk management, and responsible AI practices through measurable controls, policy enforcement, and technical safeguards for agent behaviorDrive platform adoption by creating reusable components, documentation, onboarding patterns, and developer enablement resourcesMentor engineers and provide technical leadership across AI platform initiativesEvaluate emerging tools, frameworks, and architectural patterns in generative AI and agentic systems to inform platform strategyRequired QualificationsBachelor’s degree in Computer Science, Software Engineering, Machine Learning, Data Engineering, or a related technical field; advanced degree preferredSignificant industry experience in software engineering, machine learning engineering, or AI platform development, including experience in senior or principal-level technical rolesProven track record designing and delivering production-scale AI or ML platformsStrong experience building distributed systems, APIs, microservices, and cloud-native applicationsDemonstrated experience operationalizing machine learning, generative AI, or agent-based solutions in enterprise environmentsExperience designing extensible platform capabilities that enable internal teams to build or integrate custom applications, tools, or servicesDeep understanding of software engineering best practices including testing, CI/CD, version control, code review, and system reliabilityDeep understanding of AI-native software engineering practices and experience establishing standards, governance, and best practices for the responsible use of AI coding assistants and software engineering agents across engineering teamsExperience defining architecture, standards, and reusable services for large-scale enterprise environmentsExperience leading complex technical initiatives and influencing architecture across cross-functional teamsStrong communication skills with the ability to explain complex technical concepts to varied audiencesExperience balancing experimentation speed with production engineering discipline, security, and maintainabilityTechnical Skills RequiredAI/ML platform architectureGenerative AI systems and large language model integrationAgentic workflows and orchestration frameworksMulti-agent or autonomous agent system designPrompt engineering and prompt managementWorkflow orchestration and automationAgent lifecycle managementModel evaluation, benchmarking, and performance measurementAI observability, tracing, monitoring, and loggingAPI design and service integrationDistributed systems and scalable backend engineeringCloud platforms and cloud-native deployment patternsProductionization of AI/ML servicesReliability, latency, throughput, and cost optimizationCI/CD pipelines and DevOps/MLOps practicesSecure software development and enterprise platform controlsPreferred SkillsAdvanced degree in Computer Science, Artificial Intelligence, Machine Learning, or a related disciplineExperience with enterprise AI platforms, developer platforms, or internal tooling ecosystemsExperience building frameworks or platforms that support bring-your-own-component or extensible developer patternsFamiliarity with model gateways, retrieval-augmented generation, and evaluation frameworksExperience implementing AI governance, responsible AI controls, and compliance-oriented technical solutionsKnowledge of vector databases, knowledge retrieval systems, and orchestration layers for intelligent applicationsExperience in regulated industries such as biotechnology, pharmaceuticals, healthcare, or life sciencesStrong mentoring and technical leadership experience in highly collaborative environmentsAbility to assess emerging AI technologies and translate them into practical platform capabilities#LI-HYBRIDPay Range:$188,000 - $282,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.Company InformationVertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io: Boston, MAType: Full time
$188k - $282k
Job DescriptionPosition SummaryVertex is seeking a Sr. Principal AI Engineer, Agentic AI Platform & Control Tower Ops to define and build the... ...and implementation of scalable, secure, and reusable capabilities for agentic AI, with a strong focus on retrieval-augmented...PlatformSeniorFull timeSummer work$166.64k - $250k
...SummaryVertex is seeking an Integrations Engineer, Agentic AI Platform to connect the AI/agentic platform... ...will play a key role in ensuring AI capabilities are embedded into day-to-day work at... ...such as OAuth, OIDC, SSO, service principals, secrets management, and token-based...PlatformFull timeSummer workRemote workFlexible hours2 days per week- ...stack of integrated cloud capabilities across data, edge,... ...elite technical and product engine of the Accenture Google... ...technology: the move to Agentic AI and Product-Led Operating... ...Models. As a Google Cloud Platform (GCP) Agentic AI Delivery Senior Engineer, you are a new...PlatformSeniorFull timeWork experience placementLive inWork at officeLocal areaShift work
- ...in cloud, data and AI with unmatched... ...and global delivery capability. Our broad range of... ...applied AI and data engineering. We help the world... ...foundations, AI platforms, and governance models... ...You Are:You are a Senior AI engineering... ...how generative and agentic AI is built,...PlatformSeniorFull timeWork experience placementLive inWork at officeLocal area
$75 per hour
Overview Senior AI Platform Engineer with Agentic AI & Model Context Protocol (MCP) Location: Preferred local candidates but open to 100% remote working... ...productivity. The focus is on introducing agentic AI capabilities into existing developer workflows in a practical,...PlatformSeniorRemote jobLong term contractContract workFor contractorsLocal area$182.3k - $291.5k
...Join Global Partners as Senior Director of Data Engineering to lead the architecture,... ...optimization of our enterprise data platform. This role drives the... ...of modern, AI-native data infrastructure... ...portfolio of streaming, ML, and agentic capabilities - while embedding agentic...PlatformSeniorPermanent employmentLocal areaShift work$173.43k - $211.97k
...seeking a transformative Senior Manager of AI Engineering to lead the technical strategy... ...of our next-generation agentic AI systems. In this high-... ..., leveraging advanced AI capabilities and seamless external... ...Generation (RAG), and major AI platforms (AWS, Azure, Google Cloud...PlatformSeniorFull timeWork at officeLocal areaFlexible hoursShift work- ...Integrity, and Inclusion. We weave AI into the fabric of everything... ..., is the observability platform built for control in the modern... .... We are seeking experienced engineers who can craft intuitive, fast... ...new features to core product capabilities using Go, deployed on...PlatformSeniorFull timeRemote workFlexible hours
$185k - $225k
...Overview:We are seeking a Principal Quant Engineer to work in close... ...scalable, production-grade platforms that support Acadian’... ...generation.Lead the AI centric development... ...of core platform capabilities that support signal computation... ...the use of AI or agentic coding tools (e.g....PlatformCasual workWork at officeWorldwideFlexible hours3 days per week$131k - $218.3k
Position Summary Our Deloitte AI & Engineering team to transform technology platforms, drive innovation, and help... .... Work You’ll Do As an Agentic Capability Engineer, you will operate as a... ...From entry-level employees to senior leaders, we believe there’s always...PlatformLocal area- ...modern cloud and data capabilities, and next‑generation AI—including Microsoft... ...You understand how agentic AI applies to... ...specialized Agentic AI Senior Manager in AMBG,... ...Advise on Microsoft platform application across... ...industry, data/AI engineering, and change management...PlatformSeniorFull timeWork experience placementLive inWork at officeLocal area
- Be the one building AI-powered experiences where... ...orchestration. Our platform connects people,... ...environments every day.Principal Applied AI Engineer, FinanceWe are seeking... ...advanced machine learning, agentic AI, and software... ...and hands-on builder—capable of architecting complex...PlatformFull timeWork at officeRemote workWork from homeWorldwideFlexible hours
$152k - $283k
...customers they serve. We build AI-powered software that... ..., we're looking for a Principal AI Product Engineer to be a foundational... ...in this role is when a capability belongs to the platform vs. when it belongs to a... ...your craft is shaped by agentic coding. What We're Looking...PlatformLive inWork at officeFlexible hours2 days per week3 days per week- ...Teradata Autonomous Knowledge Platform activates enterprise... ...real business value with AI. What You'll Do Lead... ...Teradata. We are seeking a Senior Manager, Software Engineering to lead teams building modern... ..., translating advanced AI capabilities into intuitive workflows...PlatformSeniorPermanent employmentFlexible hours
- ...to this mission.The AI Devex team exists to... ...operating a model-agnostic platform that powers AI coding... ...and expert-knowledge agentic workflows across the... ...acceleration.As a Senior Platform Engineer on the AI Devex team,... ...tooling that increase our capability to run long running...PlatformSeniorWork at officeRelocation
- Principal or Senior Principal, Anthropic AI Solutions (East Region)AI Systems & Platforms | Anthropic Business Unit****Please... ...combining design, engineering, and analytics expertise... ...MCP integrations, agentic workflows, and... ...and elevate AI capabilities across the organization...PlatformSeniorTemporary workWork at officeLocal area
- ...concepts to improve risk analysis, develop AI-enabled workflows, and enhance reporting... ...Version Control (Git).Experience using Agentic Programming tools (Github Copilot, Claude... ...Plotly, Dash).Familiarity with financial data platforms (such as Bloomberg, FactSet, Aladdin,...Platform
$229.9k - $262.4k
...Overview Senior Lead AI Engineer (AI Foundations, LLM Core and Agentic AI) Overview: At Capital One, we are creating... ...deliver our industry leading capabilities with breakthrough product... ...customers. Our AI models and platforms empower teams across Capital One...PlatformSeniorFull timePart timeLocal area$229.9k - $262.4k
...Overview Senior Lead AI Engineer (Gen AI Platform Services, Agentic AI) Overview: At Capital One, we are creating responsible and reliable AI systems... ...teams to deliver our industry leading capabilities with breakthrough product experiences and scalable...PlatformSeniorFull timePart timeLocal area$165k - $216.56k
...powering the era of the agentic enterprise. To usher... ...new era, we seek AI-native thinkers across... ...rapidly test emerging capabilities to discover simpler,... ...We are looking for a Senior Solution Engineer who is accustomed to... ...flexibility of big data platforms, and the elasticity...PlatformSenior- ...Information Job Title Senior Manager, AI & Developer Platform Product Management... ...Work Areas Technology & Engineering Employment Type... ...infrastructure and AI developer capabilities.Partner closely with... ...coding agents, LLM APIs, agentic workflows, and modern software...PlatformSeniorPermanent employmentFull timeWork at office1 day per week
$245k - $307.5k
...internet financial platform companies, building... ...responsible for:As the Senior Director, Arc - Agentic Economy Strategy &... ...infrastructure for AI agents. Working across... ...Developer Relations, Engineering, and Commercial... ...integrations and product capabilities that make Arc the...PlatformSeniorFlexible hours$235k - $335k
...Kymera is seeking a Senior/Executive Director, AI Strategy & Applications... ...governance of AI platforms, and partner across... ...criteriaOwn Kymera's Answer Engine Optimization (AEO) /... ...advisor on AI capabilities and limitations,... ...prompt engineering, and agentic frameworksA strong...PlatformSenior$210k - $245k
...and daily lives. We are looking for a Senior Manager, Analytics Platform to lead and scale our Analytics... ...between our Analytics and Data Platform Engineering teams, ensuring alignment on... ...practices including semantic modeling and AI-ready data infrastructure. RESPONSIBILITIES...PlatformSeniorFull time$244k - $366k
...their own destiny.Klaviyo's platform sends billions of messages and... ...scale up-market and embed AI/agentic systems throughout our product... ..., not bolted on. The Principal Engineer, Security is a hands-on IC who... ...and tooling; mentor Staff and Senior security engineers across teams...Platform$145k - $192.5k
...seeking a Cyber Threat Defense AI Security Senior Engineer to drive the integration... ...controls by leveraging agentic AI, custom-built machine learning... ...and adversarial emulation capabilities.Drive innovation in... ...enterprise cloud AI development platforms such as Azure AI Foundry,...PlatformSeniorFull timeWork at officeShift workDay shift$132.4k - $251.6k
...industry. Collins Aerospace has the capabilities, comprehensive portfolio, and... ...Communications Team is seeking an experienced Senior Principal Systems Engineer in a role committed to creating... ..., ship, submarine, or airborne platforms • Experience in Virtual Machine design...PlatformSeniorTemporary workWork experience placementWork at officeRemote workRelocation packageFlexible hours$200k - $325k
Job DescriptionWe are building an AI Engineering function to enable productivity and agentic capabilities across the firm, for end users, developers, and business teams.As a Senior AI Platform Engineer, you will design and own the shared platform that powers AI systems...PlatformSeniorFull timeWork at officeLocal area- ...opportunity for a Senior Data Scientist to... ...machine learning, and AI technologies to... ...competition, and digital platforms. This is a highly... ...science and AI capabilities.Required Skills &... ...Computer Science, Engineering, Statistics,... ...generative AI, and agentic systems • Experience...PlatformSeniorFull time
- ...DescriptionDirector of Engineering AI/Data ScienceLocation(... ..., Data Science, and platform development.Drive the... ...implementation of Agentic AI frameworks, including... ...of high-impact AI capabilities.Collaborate with architecture... ...technical leads, and senior engineers to build a...PlatformOngoing contractFull timeCasual workFlexible hours
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