Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Manager, Manufacturing Operations (2nd Shift)

$119.9k - $179.9k

Vertex Pharmaceuticals

Vertex Pharmaceuticals seeks a Manager for Manufacturing Operations to lead cell therapy production on the second shift in Boston. The role involves overseeing daily operations, managing supervisors and staff, ensuring cGMP compliance, and driving continuous improvement across manufacturing activities.

Responsibilities

  • Lead and manage daily cell therapy manufacturing operations and production schedules
  • Provide leadership and direction to Manufacturing Supervisors and frontline personnel
  • Oversee cGMP compliance including equipment operation, batch documentation, and facility audits
  • Partner with cross-functional teams on maintenance, investigations, deviations, and improvements
  • Monitor performance metrics and drive operational improvements in safety, quality, and cost

Requirements

  • Bachelor's degree in scientific, technical, or engineering discipline
  • 4+ years of experience in pharmaceutical manufacturing operations
  • Prior people leadership experience managing staff and manufacturing teams
  • Demonstrated competency in cGMP principles and regulatory requirements
  • Working knowledge of deviation management, CAPA, and change control processes
  • Proficiency with Quality by Design, Design of Experiments, and statistical process control
  • Cell therapy and aseptic manufacturing experience preferred
Vacancy posted 27 days ago
Similar jobs that could be interesting for youBased on the Manager, Manufacturing Operations (2nd Shift) in Boston, MA vacancy
  •  ...Senior Manager overseeing manufacturing operations and supervisory team at a pharmaceutical facility. Ensures safe, compliant, and efficient execution of cGMP manufacturing while driving continuous improvement and building organizational capability. Responsibilities... 
    Afternoon shift

    Vertex Pharmaceuticals

    Boston, MA
    23 days ago
  • $119.9k - $179.9k

     ...Job Description General Summary: The Manager, Manufacturing Operations manages a team and gives oversight to the day-to-day operations of...  ...Work Schedule This position supports our 1st shift operations. Availability to work other shifts may be necessary... 
    Suggested
    Summer work
    Flexible hours
    Shift work
    Day shift

    Vertex Pharmaceuticals

    Boston, MA
    5 days ago
  • $130k - $167k

     ...around us. We design, develop, manufacture, and service highly complex,...  ...looking for a Manufacturing Operations leader who brings strong...  ...partnering closely with Product Management, Engineering, Supply Chain,...  ...D, root cause analysis, and shift-left activities.Execute... 
    Suggested
    Shift work

    Veeco

    Waltham, MA
    5 days ago
  • $27 per hour

     ...– Assisting in the day-to-day management of the assigned location ensuring that parking operations are handled within contractual...  ...reports, auditing daily cashier shift reports, monitoring and checking...  ...applicable, availability to work 2nd shift, 3rd shift and/or week-... 
    Afternoon shift
    Hourly pay
    Temporary work
    Bank staff
    Flexible hours
    Shift work
    Night shift

    Metropolis Corp

    Charlestown, MA
    7 hours ago
  • $141.7k - $173.19k

     ...created role reflects the organization's commitment to operational excellence, scalable project management, and digital transformation within CMC.The Manager,...  ....Partner with Regulatory, Process Development, Manufacturing, Supply Chain, and Quality representatives to ensure... 
    Suggested
    Full time

    Intellia Therapeutics

    Somerville, MA
    2 days ago
  •  ...goods for businesses from family-owned manufacturers to some of the largest brands in the world...  ...robots are manufactured at scale and operate as a network, combining the whole fleet’...  ...’re protected without the premium. A managed 401(k) to help you plan for the future.... 
    Hourly pay
    Full time
    Contract work
    Work at office

    Tutor Intelligence

    Watertown, MA
    3 days ago
  • $124.8k - $130.8k

     ...Description Statement of Duties: The Director of Water and Sewer Operations is in charge of field operations for both the Water and Sewer...  .... Reviews work schedules and deployment of equipment. Manages on-call contracts for execution of any work not self-performed... 
    Afternoon shift
    Full time
    Contract work
    For contractors
    Work at office
    Local area
    Flexible hours

    City of Somerville

    Somerville, MA
    18 days ago
  • $136.5k - $187.66k

     ...About the Job: LaunchDarkly is looking for a Senior Program Manager to help the Revenue Operations team scale efficiently. This role drives cross-functional programs, streamlines processes, and delivers data-driven solutions that accelerate predictable SaaS revenue growth... 

    Candidate Company

    Boston, MA
    9 hours ago
  • $95k - $125k

     ...Description Job Description Job Title : Director, Ticket Operations Department : Business Intelligence & Operations Supervisor...  ...Operations is responsible for the strategic and day-to-day management of ticket operations for the Boston Celtics, Maine Celtics, and... 
    Afternoon shift
    Hourly pay
    Full time
    Work at office
    Local area
    Flexible hours

    Boston Celtics

    Boston, MA
    6 days ago
  • $97.9k - $146.9k

     ...Vertex Pharmaceuticals seeks a Manufacturing Operations Supervisor to lead second-shift cGMP operations at its Boston facility. The role involves supervising personnel, managing equipment operations, ensuring regulatory compliance, and maintaining production schedules... 
    Afternoon shift
    Shift work

    Vertex Pharmaceuticals

    Boston, MA
    a month ago
  • $100k - $120k

     ...Job Description Job Description ASSOCIATE DIRECTOR OF OPERATIONS The Associate Director for New England will play a pivotal role...  .... This position requires a results-driven professional who can manage multiple responsibilities, effectively utilize CRM tools, and collaborate... 
    Afternoon shift
    Live in
    Work at office
    Remote work
    Weekday work

    Friends of the Israel Defense Forces

    Boston, MA
    6 days ago
  • $150k - $225k

     ...Marsal Private Equity Performance Improvement Director: Operations & Manufacturing (OPEN TO ALL U.S. LOCATIONS) About Alvarez & Marsal...  ...and oversee the quality of deliverables and effectively manage the team and day-to-day relationships to ensure exceptional... 
    Full time
    Part time
    Monday to Friday
    Monday to Thursday
    Flexible hours
    Night shift

    Alvarez & Marsal

    Boston, MA
    1 day ago
  •  ...Reporting into the Regional Director of Operations, the Director of Operations will lead...  ...assigned Puttshack venue location. This role manages a multi-faceted, high volume, full-...  ...Hospitality Managers, Sales Office, and Shift leads.   ~ Collaborate with Talent and... 
    Afternoon shift
    Hourly pay
    Full time
    Temporary work
    Work at office
    Local area
    Flexible hours
    Shift work
    Weekend work

    Puttshack

    Boston, MA
    6 days ago
  • $175k - $250k

     ...Marsal Private Equity Performance ImprovementSenior Director: Operations & Manufacturing(OPEN TO ALL U.S. LOCATIONS)About Alvarez & MarsalAlvarez &...  ...models. Leadership: Experience in leading teams, managing multiple stakeholders, and driving results around executable... 
    Full time
    Part time
    Interim role
    Flexible hours

    Alvarez & Marsal

    Boston, MA
    1 day ago
  • $125.1k - $225.2k

     ...Unleash your talent and redefine what’s possible.Job Description:Parsons is seeking a dynamic Senior Rail & Transit Operations Planning Program Manager to join our growing Rail and Transit business. This is a high-impact leadership role for a seasoned professional who... 
    Full time
    Contract work
    For contractors
    Flexible hours

    Parsons

    Boston, MA
    1 day ago
  • $129.5k - $207k

    Job Description:Our OpportunityChewy is seeking a SeniorTechnical Program Manager (TPM), Platform Operations to lead high-impact, cross-functional programs across the whole Chewy ecosystem in Boston, MA.You will own delivery across critical engineer journeys and foundational... 
    Local area
    Flexible hours

    Chewy

    Boston, MA
    1 day ago
  • $119.9k - $179.9k

     ...Vertex Pharmaceuticals seeks a Manager, Manufacturing Operations to oversee daily operations of the Drug Product Facility in Boston, directing staff and ensuring cGMP compliance. The role involves process improvement, regulatory oversight, and cross-functional collaboration... 

    Vertex Pharmaceuticals

    Boston, MA
    27 days ago
  • $134.5k - $265.1k

    Position Summary Learning Business Process as a Service (LBPaaS) helps enterprises operate and continuously improve learning programs through managed services, technology, and global delivery capabilities. As a Manager, Learning Operations Managed Services, you... 
    Local area
    Visa sponsorship

    Deloitte

    Boston, MA
    5 days ago
  • $120k - $225k

     ...helping everyone design, prototype, and manufacture faster than ever before.We’re a team of...  ...Manufacturing Engineering Manager for our global headquarters team in Boston...  ...player coach on complex engineering and operational challenges. Own manufacturing technical... 
    Afternoon shift
    Contract work
    Work at office
    Local area
    Remote work
    Worldwide
    Flexible hours

    Formlabs

    Somerville, MA
    2 days ago
  • $90k - $120k

    Position Title: Manager, Air OperationsReporting To: VP, Air OperationsDepartment: Air OperationsLocation: Boston, MA (Hybrid)Position...  ...Circle Travel.We’re seeking a results-oriented Manager, Air Operations to lead critical air operational activities that support traveler... 
    Full time
    Contract work
    Summer work
    Work at office
    Immediate start
    Overseas

    Grand Circle Travel

    Boston, MA
    4 days ago
  • $150k - $200k

    JOB SUMMARYB-Stock is hiring a Senior Manager of Revenue Operations to lead the team and systems that keep go-to-market running across sales, account management, and marketing — spanning sales and marketing analytics, operations, systems, and process. This is a people-manager... 
    Contract work
    Work experience placement
    Work at office
    Remote work

    B-Stock Solutions

    Boston, MA
    3 days ago
  • $109.2k - $174.6k

    The Role:The Manager, RWE Study Operations provides operational leadership for multiple Real-World Evidence (RWE) studies and coordinates cross-functional teams to ensure successful study execution and delivery. This role requires strong project management, vendor oversight... 
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    1 day ago
  • $119.1k - $239.3k

     ...that’s why there’s nowhere like RSM.As a Manager within the Management Consulting, Life...  ...middle market firm but will be able to operate in a lean and agile environment where your...  ...government price points (e.g., Average Manufacturer Price, Best Price, Unit Rebate Amount, Average... 
    Full time
    Contract work
    Work experience placement
    Internship
    Work at office
    Local area

    RSM International

    Boston, MA
    1 day ago
  • $130.8k - $209.4k

    The Role:Moderna is seeking a Biomarker Operations Sr. Manager to support the clinical teams and to work across its clinical trials as well as with external biorepositories, assay laboratories and CROs. This position will work collaboratively across all therapeutic area... 
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    1 day ago
  • $141.7k - $173.19k

     ...Intellia Therapeutics seeks a Manager of CMC Program Operations to lead operational excellence and digital transformation for chemistry, manufacturing, and controls teams. The role combines project management oversight with AI-enabled tool design to enhance visibility... 

    Intellia Therapeutics

    Cambridge, MA
    23 days ago
  •  ...Services is seeking a Director of People & Operations —a strategic, hands-on leader with deep...  ...is tech-savvy (across property management, HR platforms, and AI tools), understands...  ...and support scheduling processes; ensure shift coverage and compliance with labor standards... 
    Afternoon shift
    Full time
    Casual work
    Remote work
    Monday to Friday
    Flexible hours
    Shift work

    Apex Concierge Services Inc

    Boston, MA
    4 days ago
  • $139.1k - $208.7k

     ...Vertex Pharmaceuticals seeks a Senior Manager for Manufacturing Operations to lead a supervisory team and oversee cGMP pharmaceutical manufacturing on the third shift in Boston. The role requires strategic operational leadership to ensure safe, compliant, and efficient... 
    Shift work
    Night shift

    Vertex Pharmaceuticals

    Boston, MA
    a month ago
  •  ...experience. Job Description Job Summary: The Production Manager reports to the Technical Director for college theater and...  ...collaboration among students, OFA, and program, facility, and operations staff, as well as other stakeholders, ensuring that production... 
    Afternoon shift
    Term time
    Work at office

    Harvard University

    Cambridge, MA
    4 days ago
  • $85k - $95k

     ...boarding school for Afghan girls, the first and only of its kind operating anywhere in the world. SOLA evacuated Afghanistan upon the...  ...mission-driven leader who thrives in a dynamic environment, can manage complex projects, coordinate diverse stakeholders, and build systems... 
    Work at office
    Remote work
    Flexible hours

    School Of Leadership Afghanistan Inc

    Boston, MA
    15 days ago
  •  ...per week onsite. Candidates MUST live within commutable distance to our office.Job DescriptionWe're looking for a Manager of Customer Service Operations to own the operational backbone of our global Go-to-Market engine. You'll sit at the intersection of Sales, Finance... 
    Contract work
    Work at office
    Immediate start
    Remote work
    Flexible hours
    3 days per week

    Nexthink

    Boston, MA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Manager, Manufacturing Operations (2nd Shift). Be the first to apply!