Senior Applied Science Manager, Amazon Sponsored Products & Brands

The Sr. Manager Applied Science will lead a cross-functional team of 30+ builders in pioneering GenAI experiences for +1.3MM Amazon Sponsored Product and Brand (SPB) advertisers. The leader will invent and build the SPB-Agent, a GenAI platform which will transform retail-media advertising for SPBadvertisers, from emerging brands to global brands selling on Amazon. SPB-Agent will serve as an intelligent advisor integrated directly into Amazon Ad Console and Selling Partner portals (Seller Central and Vendor Central). Through conversational interfaces and deep reasoning, it will help advertisers discover growth opportunities, optimize campaign performance, and execute sophisticated strategies. The leader will drive this transformation from vision to reality, directly shaping the intersection of generative AI and advertising at unprecedented scale. Key job responsibilities As a Sr. Applied Science Manager, you will: - Lead a cross-functional team of Applied Scientists, Engineers, and Product leaders. - Define and deliver the science and engineering roadmap for SPB Agent, translating business goals into agentic experiences and driving integration of the SPB-Agent into advertising applications. - Hire and develop top talent, providing technical direction and career growth guidance to scientists and engineers within and across organizations. - Stay current on research advances, industry trends, and system architectures relevant to agentic AI for SPB's advertising business. About the team The Advertiser Guidance team sits at the heart of Sponsored Products and Brands, tackling advertising's most complex challenges: how do you guide 1.3+ million advertisers-from first-time sellers to global brands-to create and manage campaigns that drive real business growth? Our advertisers span every industry, budget level, and sophistication-selling everything from handmade crafts to consumer electronics. They manage campaigns with vastly different goals: some prioritize brand awareness, others focus on conversion efficiency, and many need help understanding what's even possible. This diversity creates immense technical complexity, but also a transformative opportunity to drive impact at scale. BASIC QUALIFICATIONS * M.S. in Computer Science, Information Retrieval, Machine Learning, Natural Language Processing, Statistics, Mathematics, or related discipline * Experience in managing and growing a high-performing and diverse team of both applied scientists and engineers for at least 5 years * Experience in building large-scale machine learning and AI solutions for at least 5 years PREFERRED QUALIFICATIONS * Ph.D. in Computer Science, Information Retrieval, Machine Learning, Natural Language Processing, Statistics, Mathematics, or related discipline * Experience in building large-scale machine-learning models and infra for online recommendation, ads ranking, personalization, or search, etc. * Experience developing and deploying Agentic AI solutions * The ability to communicate complex technical concepts and solutions to all levels of the organization * Experience in Advertising Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $196,900/year in our lowest geographic market up to $340,300/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit This position will remain posted until filled. Applicants should apply via our internal or external career site.