Scientist - In Vivo

Job Description Our company's South San Francisco research laboratory is seeking an innovative drug hunter with a strong in vivo background in biology or metabolism to join the cardiometabolic disease department as an Associate Scientist. The individual will perform experiments in the laboratory with minimal guidance and supervision. The successful candidate will design, execute, and interpret complex in vivo/ex vivo/in vitro studies to support target identification, validation, and therapeutic development. The successful candidate will also possess a strong sense of intellectual curiosity to expand their technical expertise at the bench, as well as effective written and interpersonal communication skills to explain complex experiments and biological concepts to a broader scientific team. Key Responsibilities Establish key assays and model systems suitable for the mechanistic investigation of potential targets, as well as evaluation of therapeutic candidates. In vivo dosing, bleeding, and handling of small laboratory animals. Perform molecular biology, cellular biology, cell-based assay, and ex vivo sample processing and analysis. Design, perform, troubleshoot, document, analyze and interpret assigned research with minimal supervision, to support exploratory activities as well as project‑focused goals. Scour and critically evaluate current literature to identify opportunities for new and existing programs. Work independently in executing tightly controlled experiments, analyzing data, and presenting to teams within the disease area. Solve complex problems by undertaking innovative approaches and applying state‑of‑the‑art technologies. NOTE This role will be required to work on weekends in a shifted work‑week schedule (Tuesday – Saturday / Sunday – Thursday). Qualifications Education Bachelor's (with 3+ years) or Master's in chemical biology, molecular and cellular biology, pharmacology, biology or other related scientific discipline and relevant experience. Required Experience and Skills Experience in one or more of the following areas: target validation, in‑vivo model development or adipose biology. Experience with handling, dosing (oral, subcutaneous, intraperitoneal, intravenous), and bleeding small laboratory animals. Experience working with human as well as pre‑clinical tissues and primary cell lines. Experience with standard molecular biology techniques (western blotting, qPCR, etc). Works independently and is able to simultaneously handle a varied workload with strong organizational and time‑management skills. Strong communication and interpersonal skills as well as the ability to work flexibly in a dynamic team environment. Scientific curiosity, analytical mindset with a drive to own a project to understand biology, mechanism of action, and drive it through the discovery pipeline. Preferred Experience and Skills Prior industry experience. Experience in target identification, muscle biology or immunology in the context of metabolic disease. US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights, EEOC GINA Supplement. Salary Range The salary range for this role is $108,000.00 – $170,100.00. An employee's position within the salary range will be based on several factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. Benefits The successful candidate will be eligible for annual bonus and long‑term incentive, if applicable. We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits for employees and families, retirement benefits including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at . Other Details Employee Status: Regular Relocation: Domestic Visa Sponsorship: No Travel Requirements: No Travel Required Shift: 1st – Day Valid Driving License: No Hazardous Material(s): N/A Flexible Work Arrangements: Not Applicable Job Posting End Date 07/15/2026 (Job posting effective until 11:59:59 PM on the day before the listed job posting end date). Requisition ID

R405157

#J-18808-Ljbffr Merck & Co.