Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Applied Scientist

$142.8k - $274.8k

Microsoft Corporation

Overview

The Foundry Agent Platform organization within Azure AI Platform is at the forefront of building the next generation of AI-driven solutions that power Microsoft’s most innovative products and services. Our work underpins key Azure AI offerings, enabling intelligent, scalable, and reliable AI experiences across the Microsoft ecosystem.

Within Foundry Agent Platform, the Agent Performance team is focused on developing advanced tools and platforms to monitor, evaluate, optimize and self-improve AI agents. We are seeking a passionate and skilled Applied Scientist to join the Agent Performance R&D team to help integrate the latest science innovations into the Foundry Agent Platform.

In this role, you will:

  • Understand latest scientific advancements and collaborate with leading researchers to incubate cutting-edge RL techniques into the Foundry Agent Platform

  • Push the envelope on agent accuracy, experimentation and performance advancing the state-of-the-art by connecting customer needs, latest science techniques and product opportunities.

  • Collaborate closely with designers, UI-experts and engineers to ensure clear, actionable dashboards and visualizations that empower users to make trustworthy science-informed decisions.

We are looking for a Principal Applied Scientist, Agent Foundry (CoreAI) who is passionate about translating AI research into customer impact, with a deep understanding of observability and monitoring principles. If you thrive in collaborative environments and are excited to shape the future of AI agent accuracy and performance, we’d love to hear from you!

Microsoft’s mission is to empower every person and every organization on the planet to achieve more. As employees we come together with a growth mindset, innovate to empower others, and collaborate to realize our shared goals. Each day we build on our values of respect, integrity, and accountability to create a culture of inclusion where everyone can thrive at work and beyond.

In alignment with our Microsoft values, we are committed to cultivating an inclusive work environment for all employees to positively impact our culture every day.

Responsibilities

  • Help to shape the direction of Agent Foundry Platform and Agent self-improvement with industry-leading product work.

  • Collaborate with and bridge the gaps between researchers (e.g., across CoreAI, Microsoft Research [MSR] and open-source communities) to translate applied research into differentiated, production-quality features

  • Bring new technology and approaches, such as Reinforcement Learning from Human Feedback (RLHF), into production by applying long-term research efforts to drive Agent self-improvement

  • Drive negotiations across teams to ensure cutting edge technology is being applied to products in a practical way that meets key business objectives

  • Leverage and/or construct data and experimentation to rapidly iterate on and refine product opportunities in a rapidly evolving domain

  • Proactively provide mentorship and coaching to less experienced and mid-level team members by sharing expertise to build team capabilities and guiding team members in projects, and their careers

Qualifications

Required Qualifications

  • Bachelor's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research)

  • OR Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 4+ years related experience (e.g., statistics, predictive analytics, research)

  • OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 3+ years related experience (e.g., statistics, predictive analytics, research)

  • OR equivalent experience.

Other Requirements

  • Ability to meet Microsoft, customer and/or government security screening requirements are required for this role. These requirements include but are not limited to the following specialized security screenings:

  • Microsoft Cloud Background Check: This position will be required to pass the Microsoft Cloud background check upon hire/transfer and every two years thereafter.

Preferred Qualifications

  • Bachelor's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 8+ years related experience (e.g., statistics, predictive analytics, research)

  • OR Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research)

  • OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 5+ years related experience (e.g., statistics, predictive analytics, research)

  • OR equivalent experience.

  • 4+ years foundation in machine learning and applied AI techniques, including model evaluation and optimization.

  • 3+ years of experience programming in Python.

  • 1+ years of experience in fine-tuning and post-training strategies for models in production environments.

  • 2+ Experience with prompt engineering and optimization for large language models or similar AI systems

  • 3+ years experience presenting at conferences or other events in the outside research/industry community as an invited speaker.

  • 7+ years experience conducting research as part of a research program (in academic or industry settings).

  • 5+ years experience developing and deploying live production systems, as part of a product team.

  • 7+ years experience developing and deploying products or systems at multiple points in the product cycle from ideation to shipping.

Applied Sciences IC5 - The typical base pay range for this role across the U.S. is USD $142,800.00 - $274,800.00 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000.00 - $304,200.00 per year.

Certain roles may be eligible for benefits and other compensation. Find additional benefits and pay information here:

Applied Sciences IC6 - The typical base pay range for this role across the U.S. is USD $165,600.00 - $296,400.00 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $220,800.00 - $331,200.00 per year.

Certain roles may be eligible for benefits and other compensation. Find additional benefits and pay information here:

Applied Sciences IC6 - The typical base pay range for this role across the U.S. is USD $165,600 - $296,400 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $220,800 - $331,200 per year.

Certain roles may be eligible for benefits and other compensation. Find additional benefits and pay information here:

Applied Sciences IC6 - The typical base pay range for this role across the U.S. is USD $165,600 - $296,400 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $220,800 - $331,200 per year.

Certain roles may be eligible for benefits and other compensation. Find additional benefits and pay information here:

This position will be open for a minimum of 5 days, with applications accepted on an ongoing basis until the position is filled.

Microsoft is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, color, family or medical care leave, gender identity or expression, genetic information, immigration status, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran or military status, race, ethnicity, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable local laws, regulations and ordinances. If you need assistance with religious accommodations and/or a reasonable accommodation due to a disability during the application process, read more about requesting accommodations. (

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Principal Applied Scientist in Redmond, WA vacancy
  • $142.8k - $274.8k

     ...the planet Collaborate closely with backend engineers, data scientists, site reliability engineers (SREs), and product managers to...  ...Microsoft Research [MSR] and open source communities) to translate applied research into differentiated, production-quality features... 
    Principal
    Ongoing contract
    Local area

    Microsoft Corporation

    Redmond, WA
    4 days ago
  • $165.6k - $296.4k

     ...full potential of AI to build intelligent, adaptive, and transformative software. You will be a technical contributor driving the applied science foundation for observability in AI agents and multi-agent systems running at scale. This role focuses on understanding how... 
    Principal
    Ongoing contract
    Local area

    Microsoft Corporation

    Redmond, WA
    1 day ago
  •  ...Principal Applied Scientist The people at UiPath believe in the transformative power of automation to change how the world works. We're committed to creating category-leading enterprise software that unleashes that power. To make that happen, we need people who are... 
    Principal
    Work at office
    Immediate start
    Remote work

    UiPath

    Bellevue, WA
    13 hours ago
  • $150k - $200k

     ...contributions to the company’s success. SystImmune is seeking a Principal Scientist to lead the design, implementation, and ownership of a next‑...  ..., SPR, ELISA, Octet) Biophysical characterization techniques Apply structural biology knowledge to guide construct design and... 
    Principal

    SystImmune Inc.

    Redmond, WA
    13 hours ago
  • $150k - $200k

     ...significant contributions to the company’s success. Senior or Principal Scientist - AI/ML & Protein Drug Discovery This role will drive the...  ...knowledge into model architectures and training strategies. Apply ML to support antibody humanization, CDR optimization, stability... 
    Principal

    SystImmune

    Redmond, WA
    1 day ago
  • $184k - $299k

     ...with deep quantum computing domain expertise to path-find the future. As a Senior Quantum Error Correction Research Scientist for Quantum Computing Applied Research, you'll focus on technical pathfinding, helping to develop innovative technologies that advance the state... 

    NVIDIA Corporation

    Redmond, WA
    4 days ago
  • $192k - $304.75k

     ...approach to accelerated computing. We're looking for a passionate scientist at the intersection of quantum device physics, quantum...  ...time models for fault‑tolerant quantum hardware. As a Sr. Quantum Applied Research Scientist, you will help design and build real‑time models... 

    NVIDIA Gruppe

    Redmond, WA
    3 days ago
  • A leading research organization is seeking a Research Scientist IV/ Applied Perception Scientist to support their Audio team. This role involves overseeing research projects on speech quality, managing multiple projects in a dynamic environment, and requires a PhD or equivalent... 

    ManpowerGroup Global, Inc.

    Redmond, WA
    13 hours ago
  • $70 - $75 per hour

     ...research organization specializing in virtual and augmented reality technology, is seeking a Research Scientist IV to join their innovative team. As a Research Scientist IV/ Applied Perception Scientist, you will be part of the Reality Labs Research department supporting the... 
    Hourly pay
    Weekly pay
    Contract work
    Temporary work
    Flexible hours

    ManpowerGroup Global, Inc.

    Redmond, WA
    13 hours ago
  •  ...and late‑stage programs with emphasis on safety, robustness, and scalability. Author patents, publications, and regulatory documents. Apply modern synthetic organic chemistry principles, mechanistic insight, and data‑rich methods to accelerate development. Communicate... 
    Principal
    Temporary work

    Pfizer

    Bothell, WA
    4 days ago
  •  ...functional teams, lead the discovery, optimization, and nomination of new drug candidates for clinical development. Responsibilities Apply oncology and ADC pharmacology to formulate new therapeutic concepts. Lead preclinical discovery for novel ADC technologies: linker/... 
    Principal

    Scorpion Therapeutics

    Bothell, WA
    4 days ago
  •  ...an opportunity for you to learn and grow while making significant contributions to the company\'s success. We are seeking a Principal Scientist to provide technical leadership for the development of immunohistochemistry (IHC) companion diagnostics supporting oncology drug... 
    Principal
    Full time

    Systimmune

    Redmond, WA
    2 days ago
  • $170k - $210.64k

    Principal Scientist, ADC Technologies Bothell, Washington, United States Company Overview Immunome is a clinical-stage targeted oncology company...  ...drug candidates for clinical development. Responsibilities Apply extensive knowledge of oncology and ADC pharmacology to formulate... 
    Principal

    Immunome

    Bothell, WA
    1 day ago
  •  ...inclusive of diverse perspectives. Join us as we shape the future of AI and beyond. THE ROLE We are looking for a Senior Applied Research Scientist who is experienced with training large language models and/or large multimodal models. In this role, you will explore... 

    Advanced Micro Devices

    Bellevue, WA
    1 day ago
  • $140k - $210k

     ...reasoning, and multi‑step planning for foundation models. In this role, you will define the technical direction of the applied science team, mentor scientists, and partner closely with engineering to translate advanced research into scalable, production‑ready AI systems.... 
    Full time
    Work visa

    Naver U.Hub INC

    Bellevue, WA
    1 day ago
  • $106k - $176.6k

     ...safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate...  ...drive the next generation of targeted cancer therapy. As a Principal Scientist in CPAD, you will provide technical leadership to a team of... 
    Principal
    Permanent employment
    H1b
    Local area
    Visa sponsorship
    Work visa
    Relocation package

    Pfizer Belgium

    Bothell, WA
    2 days ago
  • $117.2k - $229.2k

     ...users to dramatically enhance productivity and creativity throughout their writing journey from start to finish. As a Senior Applied Scientist in the team, you will drive intelligence experience projects through their entire life cycle from idea creation through rigorous... 
    Full time
    Local area
    Work from home
    Worldwide

    Microsoft

    Redmond, WA
    7 hours ago
  • $106k - $176.6k

    Pfizer, S.A. de C.V is seeking a Principal Scientist in Bothell, WA to lead the Chemical Process and Analytical Development group. Your role will revolve around providing technical leadership, overseeing process development for drug-linkers in antibody-drug conjugates,... 
    Principal

    Pfizer, S.A. de C.V

    Bothell, WA
    1 day ago
  • $146k - $188k

     ...-stage ADCs pursuing undisclosed solid tumor targets. Position Overview We are seeking an experienced and motivated Senior/Principal Scientist in ADC Conjugation Process Development to support our growing pipeline. This role will be responsible for the optimization of... 
    Principal

    Immunome

    Bothell, WA
    1 day ago
  • $90k - $140k

     ...contributions to the company’s success. Position Summary Senior Scientist - Antibody Discovery We are seeking a highly skilled and...  ...an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. #J-18808-Ljbffr Itlearn360
    Work at office

    Itlearn360

    Redmond, WA
    4 days ago
  • $90k - $140k

     ...contributions to the company’s success. We are seeking a highly motivated Scientist / Senior Scientist to lead and support the development,...  ...Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. #J-18808-Ljbffr Systimmune
    Full time

    Systimmune

    Redmond, WA
    1 day ago
  • $60k - $85k

     ...MORE. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. #J-18808-Ljbffr SystImmune
    Full time
    Work at office
    Relocation
    Shift work
    Weekend work

    SystImmune

    Redmond, WA
    1 day ago
  • $106k - $176.6k

     ...development of chemical processes and analytical methods for novel drug‑linkers used in antibody‑drug conjugates (ADCs). As a Principal Scientist in CPAD you will provide technical leadership to process chemists engaged in route screening/selection, process development,... 
    Principal
    Permanent employment
    Local area

    Pfizer, S.A. de C.V

    Bothell, WA
    3 days ago
  • $90k - $140k

     ...The ideal candidate is a highly energetic and motivated Senior Scientist with experience in discovery and development of protein therapeutics...  ...biologics drug development. Responsibilities Establish and apply in vitro, in vivo, and in‑site models to identify and... 
    Work at office

    Systimmune

    Redmond, WA
    4 days ago
  •  ...Society of Tribologists and Lubrication Engineers is seeking a Principal Electrical Engineer in Redmond, Washington. The ideal candidate...  ...growth are prioritized. Interested candidates are encouraged to apply and make a meaningful impact through innovative electrical... 
    Principal

    Society of Tribologists and Lubrication Engineers

    Redmond, WA
    2 days ago
  • $161.01k

     ...will be notified as specific positions arise. The starting salary is $161,006 per year, along with a full benefits package. The district embraces inclusivity and encourages underrepresented individuals in education to apply. #J-18808-Ljbffr Lake Washington School District
    Principal

    Lake Washington School District

    Redmond, WA
    13 hours ago
  • A leading technology company in Redmond is seeking a Principal Security Research Engineer to protect users from cyber threats. This role requires over 7 years of experience in software development and cybersecurity, including threat research and innovative tech solutions... 
    Principal

    Victrays

    Redmond, WA
    2 days ago
  • $78.3k - $111.98k

     ...Geologist to join the Geosciences Team in our Redmond, WA office. The qualified candidate shall have broad skills in the field of applied geology and engineering geology, be registered as a Geologist or Engineering Geologist, or be capable of obtaining their license in... 
    Local area

    WSP in the U.S.

    Redmond, WA
    3 days ago
  •  ...AI Research team. This role, based in Bellevue, offers recent PhD graduates the chance to deepen their research in AI, focusing on applying machine learning to impactful real-world challenges in domains such as medicine and finance. The ideal candidate will have a PhD,... 

    Snowflake

    Bellevue, WA
    1 day ago
  • $82k - $88k

    ## Senior Associate Scientist, Drug Product DesignApplylocations: Redmondtime type: Full timeposted...  ...*Location:** Redmond, WA**Reports to:** Principal Scientist, Drug Product Design **About...  ...are you waiting for? Take the leap and apply today. We can’t wait to see where your... 
    Temporary work
    Work at office
    Flexible hours

    Evotec WD

    Redmond, WA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Applied Scientist. Be the first to apply!