Medical Director

Senior Medical Director, Clinical Development, Oncology (Remote) About the Organisation A global biopharmaceutical company is dedicated to advancing innovative treatments for patients facing serious and often underserved medical conditions. With a strong emphasis on scientific research and patient outcomes, the organisation develops therapies across areas such as neuroscience and oncology. Operating internationally, it combines cutting-edge research with a commitment to improving lives worldwide. Role Overview An experienced clinical leader is sought to head early-stage oncology development efforts. This senior role will guide the strategy and delivery of clinical programmes from first-in-human studies through early proof-of-concept phases. You will oversee a portfolio of emerging therapies, ensuring that scientific insights, biomarker strategies, and clinical execution are aligned to accelerate development. This position plays a critical role in shaping the early pipeline and influencing key investment and progression decisions. Key Responsibilities Strategic Leadership Define and lead the clinical development approach for early oncology programmes across multiple indications and treatment modalities Design early-phase trials, including first-in-human, dose escalation, and expansion studies Provide senior clinical input on portfolio prioritisation, including go/no-go decisions Integrate translational science and biomarker strategies to optimise patient selection and demonstrate early efficacy signals Clinical Oversight Provide medical leadership for ongoing early-phase studies, ensuring high standards of safety and scientific integrity Contribute to clinical protocols, regulatory submissions, and study documentation Analyse and interpret clinical and translational data to guide dose selection and programme advancement Ensure compliance with global regulatory requirements and best practices Collaboration & External Engagement Work closely with research, translational science, regulatory, and operational teams to advance programmes efficiently Support interactions with regulatory authorities and external stakeholders Engage with key opinion leaders, academic institutions, and advisory groups Contribute to partnerships and collaborative development initiatives Team Leadership Lead and develop a team of clinical professionals across early oncology programmes Build capabilities in early-stage development strategy and execution Promote a culture of accountability, innovation, and collaboration Candidate Profile Essential Requirements: Medical degree (MD required; MD/PhD advantageous) Specialist training in oncology or haematology Significant experience (10 years) in oncology drug development within the pharmaceutical or biotech industry Demonstrated leadership in early clinical development (Phase 1–2), including first-in-human trials Experience working with regulatory authorities on early-stage programmes Strong understanding of tumour biology, translational medicine, and clinical trial design Key Skills: Ability to lead multiple complex programmes simultaneously Strong analytical capabilities, including interpretation of clinical and biomarker data Excellent communication and influencing skills at senior levels Proven experience building and managing high-performing teams Compensation & Benefits Base salary range: approximately $348,000 – $522,000 annually (U.S.-based roles) Additional compensation may include performance bonuses and long-term equity incentives Comprehensive benefits package supporting health, wellbeing, and professional development Equal Opportunity Statement The organisation is committed to fostering an inclusive workplace and provides equal employment opportunities to all qualified individuals, regardless of protected characteristics.aa415a4b-8b21-40fc-a65c-70d2b25ca29a