Protein Purification Scientist

Location : Fully Onsite in Collegeville, PA Shift: 1st Shift (M-F) Compensation: $38.46/hr to $46.97/hr. Exact compensation may vary based on several factors, including skills, experience, and education. Benefit packages for this role will start on the 1st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law. Required Skills & Experience PhD in Biochemistry, Neuroscience, Molecular Biology, Cell Biology, or a related scientific discipline preferred Candidates with a Master's degree and relevant industry experience will also be considered Demonstrated hands‑on protein purification experience, preferably from tissue‑derived samples Western blotting RT‑qPCR Aseptic mammalian cell culture HTRF and/or MSD assays Nice to Have Skills & Experience Experience working with human brain tissue Experience purifying Tau protein or other aggregation‑prone proteins associated with neurodegenerative diseases Hands‑on experience with iPSC‑derived neuronal cultures Job Description We are seeking a highly motivated Protein Purification Scientist to support neurodegeneration drug discovery programs within the NeuroImmune group. The successful candidate will be responsible for the purification, quality control, and delivery of human brain‑derived Tau protein to support research aligned with the neurodegeneration portfolio. This role requires strong hands‑on expertise in protein biochemistry, purification from tissue samples, molecular and cell biology techniques, and assay execution. The scientist will work closely within a collaborative team environment, generating high‑quality data, maintaining accurate records, and communicating results effectively to project stakeholders. Key Responsibilities Execute Tau protein purification from human brain tissue using established protocols. Perform end‑to‑end purification workflows, including protein isolation, enrichment, quality control, and final product delivery. Conduct analytical and functional assays, including: HTRF assays MSD assays Western blotting RT‑qPCR ELISA‑based assays High‑content imaging Perform and maintain aseptic cell culture procedures. Support iPSC‑derived neuronal culture experiments as required. Analyze, interpret, and present experimental data to project teams and management. Maintain accurate and timely documentation in electronic laboratory notebooks (Signals ELN). #J-18808-Ljbffr