Senior Marketing Manager

Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

We are seeking a Senior Marketing Manager, Global Marketing with a background in promotional execution and tactical marketing within the biotechnology or pharmaceutical industry. This individual will play a key role in driving awareness and consideration with patients and HCP in support of our lead product in the rare disease space. The Senior Marketing Manager will build and execute brand-aligned print and digital marketing materials to reach patients and healthcare providers, translating brand strategy into high-quality, compliant promotional tactics in metabolic diseases. This individual will support the day-to-day implementation of marketing tactics across channels, participate in brand strategy development and work closely with cross-functional teams, and the field to ensure flawless execution.

Key Accountabilities/Core Job Responsibilities :

• Builds and executes brand-aligned print and digital marketing materials, including patient- and HCP-facing promotional pieces, websites, digital ads, and sales support tools, to drive awareness, consideration, and engagement.
• Manages day-to-day execution of targeted omnichannel marketing tactics across owned, earned, and paid channels, ensuring materials are delivered on time, and aligned with brand strategy.
• Engages and collaborates with patient advocacy groups, the patient community, and other critical stakeholders to deepen understanding of the patient journey and ensure support programs and materials meet the needs of patients and healthcare professionals alike.
• Shepherds promotional materials through Medical, Legal, and Regulatory (MLR) review to ensure timely, compliant approval, partnering closely with Compliance to maintain adherence to promotional and regulatory standards
• Collaborates with cross-functional team members toinform market research and secondary analysis used to identify patient and HCP trends, needs, and challenges.
• Supports planning and on-site execution of medical conferences, congresses, and advisory boards, including development of booth materials, leave-behinds, and other sales support tools.
• Tracks and reports on tactical performance metrics, such as material utilization, digital engagement, and campaign reach, to inform ongoing optimization and coordinates with field/sales teams to ensure effective integration of marketing tactics into commercial execution.

Qualifications:

• Typically requires a Bachelor’s degree in Marketing, Business, Life Sciences, or a related field and 10+ years of overall experience, including biotechnology or pharmaceutical marketing experience.
• Experience with promotional execution or tactical marketing is preferred.
• Industry Knowledge: Understanding of biotech or pharmaceutical market dynamics, promotional and regulatory requirements, and the MLR review process.
• Execution Mindset: Strong attention to detail and ability to translate brand strategy into high-quality, on-time promotional materials and tactics, with a data-driven approach to optimization.
• Communication Skills: Excellent verbal and written communication skills, with the ability to convey complex information clearly and empathetically to patients and healthcare providers.
• Collaboration: Proven ability to work effectively across functions and lead collaborative initiatives with internal and external stakeholders.

• Project Management: Exceptional organizational skills with experience managing multiple projects, agency and vendor relationships, timelines, and priorities in a fast-paced environment.

Salary Range: $151,000.00 to $196,000.00 . Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at

This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.