STAFF SCIENTIST

Closing date: December 25, 2026 Title: STAFF SCIENTIST Employee Type: Other Academic Department: Center of excellence-Cancer Campus Location: CANCER CENTER/SETON BLDG./2025 Job Summary/Basic Functions The Staff Scientist Staff Scientist will investigate the critical intersection of host metabolic health and tumor biology. Specifically, they will study how obesity-induced systemic changes drive metabolic reprogramming and epigenetic remodeling in prostate cancer. Research will place special emphasis on how these dual mechanisms converge to promote therapeutic resistance and lineage plasticity, with the goal of identifying novel therapeutic targets. The Staff Scientist will lead projects investigating how obesity alters the prostate tumor microenvironment, focusing on crosstalk among adipocyte-derived factors, tumor metabolism, and epigenetic states (e.g., histone modifications, DNA methylation). Uncover pathways that promote survival and lineage plasticity under therapeutic stress, including androgen deprivation therapy (ADT) and next-generation anti-androgens. They will be responsible for Multi-Omic Integration: Design and execute high-throughput multi-omic workflows that integrate data from RNA-seq, ChIP-seq, ATAC-seq, and metabolomics. The Staff Scientist will also apply CRISPR-Cas9 genetic screens and targeted gene editing to functionally validate candidates that drive drug resistance, conduct independent computational analyses and develop pipelines to interpret complex multi-omic data and, help with the preparation of high-impact manuscripts and actively pursue extramural funding. Minimum Qualifications Required Education: PhD Required Field of Study: Basic Science, Health Science, Bioinformatics, or related field Number of years required to perform the job: 0 - 2 years Type of experience required to perform the job: Experience in a research environment Substitution: MD or DDS are also acceptable Comprehensive benefits are available to eligible employees and their dependents health, life, dental, and vision insurance flexible spending accounts retirement plans generous annual and sick leave 14 paid holidays per year an employee health primary care clinic Other employee benefits include full-service credit union wellness benefits featuring complementary fitness center membership for employees and their spouses employee assistance program campus assistance program pet insurance option See following link for more details on our benefits offerings: LSUHSC, New Orleans - Benefits More information about these benefits can be found on this webpage: Additional Benefits #J-18808-Ljbffr LSU Health Sciences Center New Orleans