Director, Medical Science Liaison

Compass Pathways plc (Nasdaq: CMPS) is a biotechnology companydedicatedto unlocking urgently needed new treatment options in mental health care.

The Company is headquartered in London, UK, with a U.S. office in New Jersey. We believe mental health patients deserve the possibility of a better future. Our initial focus is developing COMP360 psilocybin, a proprietary, investigational, synthetic psilocybin treatment under evaluation for treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD). COMP360 is a potentially first-in-class treatment and has Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA), as well as Innovative Licensing and Access Pathway (ILAP) designation in the UK for TRD.

We are leading the world’s largest classic psychedelic clinical program in TRD, and building upon that robust foundation, we are executing a late-stage trial evaluating COMP360 for PTSD, another condition with high unmet need. Our goal is to advance treatments that move the field of psychiatry towards treatment options that offer rapid onset and sustained durability with infrequent dosing. - Compass Pathways

Job overview:

The Director of Medical Science Liaison (Western US) at Compass Pathways will lead and develop a high-performing field medical team focused on impactful scientific engagement within the neuroscience and mental health community. This role is responsible for translating Compass’s medical strategy into effective field activities, overseeing MSL operations across a defined region, and ensuring consistent, high-quality scientific exchange with external stakeholders.

The Director will drive execution of the national medical affairs plan, coach and mentor MSLs to enhance scientific credibility and performance, and partner closely with cross-functional teams to ensure that field insights help inform medical strategy, clinical development, and educational initiatives. At this level, the role also supports the growth of Compass’s treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD) franchises by reinforcing scientific leadership, shaping medical engagement plans, and advancing relationships with key external experts and thought leaders.

Location: Remote on the West Coast, USA.

Reports to : Senior Director, Medical Science Liaison.

Roles and responsibilities:
(include but not limited to)

• Lead, coach, and develop a high-performing MSL team within a region, setting clear expectations for scientific excellence, compliance, and professional growth
• Foster a culture of scientific rigor, collaboration, accountability, and continuous improvement within Field Medical
• Translate medical strategy into effective field execution, ensuring consistent, high-quality scientific engagement across territories
• Oversee territory planning, stakeholder prioritization, and deployment of field medical resources
• Ensure the timely collection, synthesis, and communication of actionable medical insights from the field to inform clinical development, medical strategy, and education planning
• Maintain awareness of emerging science, treatment landscape developments, and competitive activity relevant to TRD and PTSD
• Support medical education initiatives, advisory boards, and scientific congress engagement at the regional or national level
• Contribute to the evolution of Medical Affairs processes, training, tools, and metrics to support a growing field medical organization
• Liaise cross-functionally with Clinical Development, Market Access, Government Affairs, and other internal teams to align field medical activities with organizational priorities

Candidate Profile:

• Advanced scientific training with associated credentials (e.g., PhD, PharmD, PMHNP, MD)
• At least 3 years of Medical Science Liaison experience
• Proven field medical leader with demonstrated ability to manage projects and cross-functional relationships
• Preference for candidates with background/experience in neuroscience, psychiatry or psychology
• Experience managing and supporting direct reports required
• Experience in pre-commercial or early-launch environments preferred
• Ability to travel up to 50-75%, including overnight stays and weekends, as needed
• A thoughtful leader
• Highly organized and accountable
• Excellent verbal and written communication, listening skills, and emotional intelligence
• Proven experience of self-motivation, accountability, integrity & teamwork
• Passion for improving and transforming mental health – full alignment with Compass values

Compensation Description (annually):

Our compensation package for permanent hires includes base salary, discretionary bonus, and equity, alongside our comprehensive benefits offering.

Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and work location.

These include f lexibility & generous time off, parental & reproductive support, health & medical, mental health & wellbeing and Financial health.

Equal opportunities:

Reasonable accommodation
We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know.

UK applicants

We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability.

US applicants

Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law.

Sponsorship :

Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying.

Data Privacy:

All data is confidential and protected by all legal and data privacy requirements, please see our recruitment Privacy Notice to learn more about how we process personal data.