Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Staff/Principal Machine Learning Engineer

Full-time

Epia Neuro

About Us

Epia Neuro is a neural technology company developing intent-driven systems that restore function and independence for people living with neurological conditions. Our platform integrates implantable neural interfaces, adaptive algorithms, and assistive devices to translate neural intent into real-world action. Our initial focus is stroke-related motor impairment, with planned expansion into cognitive decline and other neurological disorders.

The Role

We have a strong research group driving early brain-computer-interface (BCI) algorithm development. We are looking for someone with deep, hands-on BCI machine learning (ML) expertise to own neural decoding and carry it from validated research approaches to real-time algorithms running in human clinical studies. This is where applied BCI work gets real: your models decode intent from actual participants, under the constraints of a live clinical program.

This is a senior individual-contributor leadership role, open at the Staff or Principal level depending on skills and experience. You will set ML technical strategy across decoder design, the decoding platform, and system architecture. Your focus is neural decoding, but your influence won't stop there: you will help raise the bar for ML engineering and modeling practices across the company. You will stay hands-on, working closely with our research team and with Software, Firmware, Hardware, and Robotics.

How We Work

  • We are intentional. We prioritize and are thoughtful about how we use others' time.

  • We care for others. We prioritize safety both for patients and one another.

  • We own outcomes, not just tasks. Our work demands the highest standards because it impacts real patients and real lives.

  • Humility is a strength. We are honest about what we know and what we don't know. Getting it right matters more than being right.

Location

This role is based out of the San Francisco Bay Area and expected to work on site from our Alameda headquarters 2–3 days a week.

Key Responsibilities

Technical Direction and Strategy

  • Own ML technical strategy for neural decoding, from validated approaches through real-time algorithms deployed in human clinical studies, spanning decoder design, the decoding platform, and system architecture.

  • Define data collection, labeling, and evaluation protocols for neural and behavioral data, and set performance criteria tied to clinical use.

  • Contribute to long-term BCI and machine learning platform strategy.

Decoding and Deployment

  • Partner with our research team to take neural decoding approaches from concept through validated prototype, including model design, training, and evaluation.

  • Develop and improve real-time, closed-loop decoding of neural intent, including online calibration, decoder adaptation, and robustness over time.

  • Own productization of the decoding algorithms, taking validated approaches to a deployable real-time inference runtime that meets latency and power budgets on the device.

  • Own integration of decoding models into the broader medical device product across Software, Firmware, Hardware, and Robotics.

  • Lead the ML side of human clinical study deployment, accounting for signal non-stationarity, session-to-session variability, limited participant time, and clinical-trial safety and regulatory constraints.

  • Lead debugging and root-cause analysis across the ML, firmware, and controls boundaries.

Standards and Cross-Functional Leadership

  • Set ML engineering standards, documentation practices, and test methodologies within our regulated software lifecycle, and review the work of other engineers against them.

  • Mentor engineers across the ML function and strengthen the team's technical depth.

  • Represent ML technical positions in regulatory strategy, partner discussions, and work with scientific advisors.

Qualifications

  • PhD in computational neuroscience, machine learning, or a related field is expected.

  • 4-8+ years developing and deploying BCI algorithms in an industry or product setting, with a track record of owning technical direction at a scope that spans teams.

  • Production-quality Python and strong software engineering fundamentals, including testing, code review, and maintainable design in a collaborative codebase.

  • Deep expertise in neural signal processing and real-time, closed-loop decoding, calibration, and adaptation.

  • A working understanding of the practical constraints and failure modes of real BCI clinical trials.

  • Excellent communication and cross-functional collaboration skills.

Preferred Qualifications

  • Direct experience leading neural decoding through an end-to-end human clinical deployment.

  • PhD or postdoctoral training in a leading neural prosthetics, motor systems, or BCI research lab.

  • Proficiency in C++ or embedded development for an inference runtime, and edge or on-device ML.

  • Familiarity with safety-critical or regulated systems, such as medical devices (IEC 62304, ISO 13485, design controls).

Physical Requirements

Ability to work on site in a lab environment, including participating in hands-on data collection and bench testing with prototype hardware. Requires manual dexterity for handling devices, some standing during test and integration sessions, and the ability to safely operate lab equipment.

Benefits

Full-time employees are eligible for the following benefits listed below.

  • Competitive base salary with equity

  • 100% of healthcare coverage for you and your dependents

  • Generous vacation policy

  • Paid parental leave

  • Work from our beautiful waterfront office in Alameda, CA, with access to collaborative spaces and labs.

Vacancy posted 13 hours ago
Similar jobs that could be interesting for youBased on the Staff/Principal Machine Learning Engineer in Alameda, CA vacancy
  • Senior ML Operations Engineer We are seeking a Senior ML Operations Engineer with advanced Python and Flask, back-end API engineering with Swagger expertise for a multi-year engagement to work with a foremost Healthcare IT Solutions Group in their Innovations Project Team... 
    Suggested

    Samprasoft

    Oakland, CA
    1 day ago
  • $1,000 per month

    Machine Learning Engineer As a Machine Learning Engineer at Elicit, you'll build products and workflows...  ...(L4): $220-260K + equity Expert/Staff (L5): $250-320K + significant equity We...  ...level or above. We'd love to meet staff/principal level contributors as well. We also offer... 
    Suggested
    Work at office
    Local area
    Remote work
    Home office
    Relocation package
    Flexible hours

    Elicit

    Oakland, CA
    5 days ago
  •  ...Every day, our community of students, parents, teachers and staff come together to learn and grow so that every child’s aspirations are within...  ...and instruction needed to be successful! The Assistant Principal works closely with the Principal to manage all the functions... 
    Suggested
    Full time
    Work at office
    Home office

    Aspire Public Schools

    Oakland, CA
    13 hours ago
  • $200k - $330k

    Machine Learning Research Engineer Emeryville, California, United States; Hybrid (2-3 days on-site) Profluent is the frontier AI lab for biology. Profluent builds powerful foundation models for all of life's molecules, unlocking solutions that transform medicine, agriculture... 
    Suggested

    Profluent

    Emeryville, CA
    1 day ago
  • $105k - $123k

     ...potential. Position Description Assistant Principals (APs) at Rocketship are charged with...  ...grade level as well as instructional support staff. APs lead their grade levels by driving...  ...expected to teach for three or more weeks to learn the curriculum and model. Other duties... 
    Suggested
    Local area
    Flexible hours

    Rocketship Public Schools

    Oakland, CA
    4 days ago
  • $15k

     ...company that applies state-of-the-art AI and machine learning techniques to real-world problems in...  ..., and more.As a Senior Machine Learning Engineer on one of Voleon's Research teams, you will partner directly with research staff to advance our quantitative trading... 
    Work at office
    Local area

    The Voleon Group

    Berkeley, CA
    a month ago
  • mZero in Emeryville, CA is looking for a Full-time, in-office ML systems engineer to build reliable data pipelines from assay recordings to models and actionable recommendations. You will own ingestion, validation, versioning, and joining of video, metadata, compound records... 
    Full time
    Work at office

    mZero

    Emeryville, CA
    2 days ago
  • $160k - $260k

     ...interfaces between computer vision, molecular models, active-learning systems, and the lab workflow Improve developer and...  ...Required qualifications Strong production software engineering experience in Python and modern machine-learning or data systems Experience deploying and... 
    Full time
    Work at office
    Shift work

    mZero

    Emeryville, CA
    2 days ago
  • $150k - $250k

     ...Responsibilities Develop deep learning models for a variety of...  ...Computer Science, Mechanical Engineering, Electrical Engineering, or equivalent...  ...in any field related to machine learning, as evidenced by top...  ...as the team grows (for Sr Staff level candidates) \n $150,... 
    Full time
    Local area

    Bluespace

    Oakland, CA
    13 hours ago
  • $200k - $250k

     ...Description Job Description Atomic Machines is ushering in a new era of...  ...: We are seeking an MLOps Engineer to join our AI and Modeling...  ...that takes AI and machine learning models from experimentation...  ...from early in career though Staff (L4 through L6). We'll determine... 

    Atomic Machines

    Emeryville, CA
    17 days ago
  • $25 - $35 per hour

     ...motivate student-athletes to participate and sustain their interests in the program. Be a positive role model for students, coaching staff, and the College Prep community. Ability to supervise, organize, and motivate a coaching staff at all levels Working... 
    Visa sponsorship
    Work visa
    Flexible hours
    Afternoon shift

    The College Preparatory School

    Oakland, CA
    5 days ago
  •  ...Catholic school in California is seeking a dedicated and visionary Principal to lead and enhance the educational environment. The...  ...requires a strong commitment to the integration of faith and learning within the school community. Submit applications by February 6... 

    Sacramento

    Alameda, CA
    13 hours ago
  • $151k - $177.5k

     ...building a better lithium-ion battery from the inside out today. We engineer and manufacture ground-breaking battery materials that...  ...execution speed Develop Models That Matter Build and deploy machine learning models for anomaly detection, fault classification, process... 

    Sila

    Alameda, CA
    18 days ago
  • SAR Academy in Emeryville is seeking dedicated Head Teachers for the 2026-2027 school year in our Early Learning Center. Candidates should foster curiosity and creativity in young children while maintaining a warm and inclusive classroom environment. Responsibilities include... 

    SAR Academy

    Emeryville, CA
    1 day ago
  •  ...educational day school in Riverdale, NY, is seeking dedicated and passionate Head Teachers for the 2026-2027 school year in our Early Learning Center (Nursery-Kindergarten). We are looking for educators who foster curiosity, creativity, and a love of learning in young... 

    SAR Academy

    Emeryville, CA
    1 day ago
  •  ...preparing for a procedure, researching a rare condition, or learning from experts across thousands of specialties. We're...  ...love to talk. The Opportunity:  We're looking for a Principal AI/ML Engineer to lead the architecture and development of Vumedi's AI-powered... 
    Work at office
    Worldwide
    Monday to Friday
    3 days per week

    VuMedi Inc.

    Oakland, CA
    6 days ago
  • $228k - $340k

     ...Everlaw is looking for a Staff/Principal AI Engineer to help design and execute our overall technical strategy of applying AI in our product, directly...  ...organization. You’ll also collaborate with (and learn from) a community of other staff and principal engineers with... 
    Full time
    Work at office
    Local area
    Remote work
    Flexible hours
    3 days per week

    Everlaw

    Oakland, CA
    13 hours ago
  • A local educational institution is seeking a new Principal to provide overall leadership and vision, starting July 1, 2026. This role...  ...requires overseeing academic programs and integrating faith with learning. The successful candidate will engage with the community,... 
    Local area

    Catholic Diocese of Gary

    Alameda, CA
    4 days ago
  • A regional educational organization in California is seeking an experienced Principal starting July 1, 2026. The Principal will lead academic and student affairs, oversee administrative operations, and serve as a role model in a faith-based educational environment. The... 

    Catholic Diocese of Sacramento

    Alameda, CA
    1 day ago
  • $126.23k - $138k

     ...across nursing programs. Guide faculty in developing courses and learning experiences aligned with program learning outcomes and...  ...Hand and finger dexterity for computer, text, calculator, copy machine, and telephone use Must be able to express or exchange ideas... 
    Full time
    Work at office
    Local area
    Shift work

    Samuel Merritt University

    Oakland, CA
    1 day ago
  • Requirements prior to the first day of coaching: NFHS Certification (First Aid, Health and Safety, and Fundamentals of Coaching) CPR/First Aid Certification Minimum Education Requirements: High School Diploma (Bachelor’s Degree preferred) from an accredited...

    Leadership Public Schools

    Hayward, CA
    more than 2 months ago
  • $65k - $70.3k

     ...for students in Grades K-12 with diverse learning needs. You’ll lead and inspire teachers,...  ...organization. Coaching teachers and staff in creating safe, engaging, and...  ...working in an educational leadership, school principal, administrator or related position. Prior... 
    Work at office
    Flexible hours

    Spectrum Center Schools and Programs

    Oakland, CA
    2 days ago
  • Role: ML/AI Engineers (This role is open to US Citizens, Green Card holders, GC-EAD only. We do not sponsor visas.) Summary: Adidev is looking for an adept Machine Learning Engineer to take the helm in deploying advanced machine learning models, with a special emphasis... 
    Remote work
    Visa sponsorship
    Relocation package

    Adidev Technologies Inc

    Oakland, CA
    6 days ago
  • $163k

     ...Finance Job Level: Manager/Principal Business Unit: Technology &...  ...a Principal Data Scientist (AI Engineer focused) to serve as the chief technical staff member within Enterprise AI CoE...  ...AI, agentic systems, machine learning, and enterprise data science.... 
    Work experience placement
    Work at office
    Local area
    Remote work

    Pacific Gas And Electric Company

    Oakland, CA
    2 days ago
  •  ...externally. Ensure monthly disaster drills compliance. (earthquake, fire, shelter in place) Manage human resource functions for staff program staff and ensure staffing levels are compliant to regulatory standards and regulations. Qualifications: Bachelor of... 
    Work from home

    Clausen House

    Oakland, CA
    14 days ago
  • $106.6k - $200k

     ...40 countries. How you'll make an impact: Our Ad Sales Engineering organization builds the technical backbone that enables advertisers...  ...directly impact company revenue. We are looking for a Staff Python Engineer to provide technical leadership across both:... 
    Temporary work
    Local area
    Worldwide

    Sirius XM Radio Inc

    Oakland, CA
    3 days ago
  • YMCA of the East Bay seeks a Preschool Teacher to deliver developmentally appropriate experiences aligned with Head Start and California guidelines. You will create warm classrooms, observe children, and tailor activities to individual progress while partnering with families...

    Ymcatc

    Hayward, CA
    1 day ago
  • $90k - $180k

     ...Working at AbbottAt Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live...  ...discipline including Mathematics, Statistics, Physics, or Engineering Minimum of 4 years of relevant work experience with degree or sufficient... 
    Work experience placement
    Worldwide

    Abbott

    Alameda, CA
    18 days ago
  •  ...entry-level software programmers, Java full stack developers, Python/Java developers, data analysts/data scientists, and machine learning engineers. Who Should Apply Recent computer science/engineering/mathematics/statistics or science graduates looking to make their careers... 
    H1b

    SynergisticIT

    Oakland, CA
    1 day ago
  • California State University - East Bay is seeking temporary, part-time Fieldwork Supervisors for Fall Semester 2026 and Spring Semester 2027. The role involves observing students during their fieldwork experiences in diverse preschool-12th-grade settings. Candidates must...
    Temporary work
    Part time

    California State University - East Bay

    Hayward, CA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Staff/Principal Machine Learning Engineer. Be the first to apply!