Sr. Manager, Strategic Operations & Innovation

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

About the Role

McKesson’s Provider Solutions business is transforming how independent specialty and oncology practices operate, grow, and adopt innovation. We are seeking a Sr. Manager, Strategic Operations & Innovation to lead execution across a portfolio of strategic initiatives, operational transformation efforts, and innovation programs.

This role serves as the operational leader for complex, cross-functional programs, translating strategy into measurable outcomes. You will drive portfolio governance, delivery planning, stakeholder alignment, risk management, and organizational readiness while partnering across business, technology, data, finance, and operations teams.

What You’ll Do

• Lead execution of a portfolio of strategic initiatives, ensuring priorities, timelines, resources, and dependencies are aligned to business objectives.
• Develop and maintain integrated program plans, milestones, risks, issues, and key decisions across multiple workstreams.
• Drive program governance, operating reviews, executive updates, and decision-making processes.
• Partner with business leaders, product teams, technology teams, and external vendors to coordinate delivery and resolve obstacles.
• Manage cross-functional dependencies and ensure accountability for achieving program milestones.
• Develop executive-level presentations, business reviews, and portfolio reporting for senior leadership.
• Identify, assess, and mitigate program risks while escalating critical issues and recommendations as needed.
• Support innovation and commercialization initiatives, helping new solutions transition into sustainable operating models.
• Lead change management and stakeholder engagement activities to promote adoption and organizational readiness.
• Establish operating rhythms, performance tracking, and governance processes that improve execution and business outcomes.

Basic Requirements

• Bachelor's degree or equivalent experience.
• Typically requires 7+ years of experience in strategic operations, program management, business transformation, management consulting, operational excellence, innovation, or related fields.
• Experience leading complex cross-functional programs involving multiple stakeholders and workstreams.
• Experience creating and managing program roadmaps, project plans, dependency tracking, and executive reporting.
• Demonstrated success driving initiatives from strategy through implementation and operational adoption.
• Experience presenting recommendations, progress updates, and business insights to senior leaders.

Preferred Skills/Experience

• MBA or other advanced degree.
• Experience within healthcare, specialty care, pharmaceutical distribution, or highly matrixed enterprise organizations.
• Experience supporting innovation, incubation, commercialization, or new business initiatives.
• Knowledge of portfolio management, organizational change management, and operational transformation methodologies.
• Experience managing third-party vendors, statement-of-work (SOW) engagements, and delivery governance.
• Proficiency with project and portfolio management tools, reporting platforms, and AI-enabled productivity solutions.
• Strong facilitation, communication, stakeholder management, and executive influence skills.
• Ability to thrive in fast-paced, evolving environments with changing priorities.

Travel / Physical Requirements

• Ability to travel up to 20%.
• General office environment with the ability to work using standard office technology and equipment.

This position offers the possibility of a hybrid work arrangement based on recent updates to our in-office/work‑from‑home model. If located in DFW area, the selected candidate may be expected to work on‑site at our Las Colinas office a minimum of two (2) days per week, with the remaining days worked remotely. Specific in‑office days may be designated according to team needs and business priorities.

McKesson complies with all applicable U.S. immigration laws and regulations. The Company does not provide employer support or sponsorship for any immigration related employment benefit for this role.

Applicants must be currently authorized to work in the United States on a fulltime basis without the need for employer support or sponsorship now or in the future. This includes having the legal right to work in the United States without the need for McKesson support or sponsorship for any immigration related employment authorization (e.g., H1B, O1, E3, H1B1, TN, F1 OPT, F1 STEM OPT, F1 CPT, etc.) now or in the future.

If you will require McKesson to provide immigration support or sponsorship now or in the future, you should not apply for this role.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$126,000 - $210,000

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com .

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) View email address on aiapply.co or (Canada) View email address on aiapply.co . Resumes or CVs submitted to this email box will not be accepted.

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