Scientist, Safety Pharmacology

Job Description The Nonclinical Drug Safety (NDS) division at our company is seeking a motivated and talented biomedical engineer or integrative systems scientist with experience in signal processing and/or computational modeling using physiologic signals to join our Safety & Exploratory Pharmacology group. The Safety & Exploratory Pharmacology (SEP) collaborates with our discovery research, preclinical, and clinical development partners to identify and develop effective, safe therapeutics. SEP utilizes a purposeful blend of standard screening tools, regulatory-enabling assays, fit‑for‑purpose capabilities and forward‑looking innovative solutions to understand potential major organ system pharmacodynamic risk to influence drug development strategy. Key Responsibilities Analyzing physiologic signals to contribute to risk assessment evaluations and developing data visualizations for scientific exploration. Building new in vivo analysis tools (signal processing, machine learning, AI) for nonclinical data and refining or developing new endpoints. Working with external vendors to identify and incorporate potential solutions. Collaborating with internal data science and IT teams to implement data tools. Integrating new analysis workflows into SEP. Contributing to SEP initiatives to develop and characterize novel alternative methods (NAMs) with in vitro scientists. Qualifications Education Bachelor’s (with 3+ years) or Master’s in Biomedical Engineering, Bioengineering, Computational Biology or related scientific field. Relevant experience in the collection and computational analysis of physiologic signals (e.g., ECG, EEG, blood pressure) and a background in pharmacology, physiology, biology, biomedical sciences, or toxicology. Required Experience and Skills Experience with nonclinical signal analysis and/or algorithm development. Proficiency with programming tools (Python, MATLAB, R) for physiological signal analysis, feature extraction, and data interpretation. Ability to work within teams as a contributor and enable collaborations across departments that deliver current needs and future capabilities. Ability to collaborate with both laboratory scientists and data scientists/IT specialists. Motivation and enthusiasm to expand programming/analysis skillset and learn new software tools. Excellent communication skills and ability to translate complex technical issues to laboratory scientists. Preferred Experience and Skills Experience with nonclinical data acquisition. Experience with machine learning and/or artificial intelligence tools and workflows. Experience with statistical and data visualization tools and libraries. Experience with cloud computing environments. Prior experience in cardiovascular, neuroscience, or respiratory endpoints. Previous exposure to data science best practices and reproducibility. Prior experience working in a multidisciplinary environment within the Pharmaceutical Industry. Willingness to influence safety pharmacology science through active participation in external consortiums, publications, and/or scientific presentations. Compensation & Benefits Salary range: $87,300.00 - $137,400.00. The successful candidate will be eligible for annual bonus and long‑term incentive, if applicable. We offer a comprehensive package of benefits including medical, dental, vision, healthcare and other insurance benefits (for employee and family), retirement benefits including a 401(k), paid holidays, vacation, and compassionate and sick days. EEO Statement As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. #J-18808-Ljbffr Merck & Co.