Sr Computational Biologist (Clinical Biomarkers & Outcomes)
$145k - $180kFoundation Medicine Inc
About the Job The Sr Computational Biologist position sits within the Computational Discovery team and is responsible for building advanced algorithms and technical features that will drive R&D's innovation roadmap. This role leverages multi-modal data, including large scale genomics, real-world clinical outcomes, and imaging datasets, to identify and establish feasibility of novel biomarkers and therapeutic targets. The Sr Computational Biologist contributes as a subject matter expert in cross-functional initiatives to identify opportunities for growth and innovation that can advance FMI's assay and data product capabilities. This position requires a deep understanding of cancer biology and bioinformatics, as well as the ability to communicate complex findings to internal and external stakeholders.
Key Responsibilities
Key Responsibilities
- Utilize statistical expertise to explore multimodal data and lead scientific investigations into mechanisms of oncogenesis, prognostic and predictive biomarkers, drug resistance, and disease monitoring.
- Manage and/or support code bases/repositories and dataset versioning and quality control.
- Represent Computational Discovery to cross-functional departments and leadership teams to refine product strategy.
- Collaborate with clinical partners in translational research projects that result in abstracts and publications.
- Communicate results to both technical and non-technical stakeholders.
- Other duties as assigned.
- PhD in a life science or mathematical field with a clinical focus and 4+ years of industry or post-doctorate experience within Cancer Biology, Bioinformatics, Biochemistry, or another related life science; OR Master's degree in a life science or mathematical field with clinical focus and 6+ years of industry experience within Cancer Biology, Bioinformatics, Biochemistry, or another related field
- Proficiency with one or more of the following scientific computing languages: Python, R, Matlab, or Java
- Practical graduate and post-doctoral experience exhibited by first-author publications
- Subject matter expertise in one of the following areas: cancer genomics, bioinformatics, biostatistics, or machine learning
- Working knowledge of NGS technology, biomarker development, and real-world clinical outcomes
- Working knowledge of clinical nomenclature including line of therapy, stage, ECOG, and the patient journey in oncology
- Experience with computational technologies such as databases (SQL), cloud computing (AWS), and deep learning (AI)
- Experience managing collaborations with multiple stakeholders
- Experience mentoring and developing junior scientists
- Translational research experience and ability to analyze and critically interpret scientific literature
- Understanding of HIPAA and the importance of patient data privacy
- Commitment to reflect FMI's values: Integrity, Courage, and Passion
Vacancy posted 5 days ago
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