Associate Scientist, In vivo Pharmacology, Inflammation

Associate Scientist, In Vivo Pharmacology, Inflammation What You Will Do In this vital role you will work in a highly dynamic in vivo pharmacology team executing in vivo preclinical disease models and in vitro assays in the vivarium and lab supporting pipeline programs. Key Responsibilities Perform hands‑on in vivo work primarily mice, possibly rats in the vivarium daily. Provide technical support for studies, dosing, sample/tissue collection, health checks, study setup and take down. Work side‑by‑side with scientists/senior scientists to execute and help design experiments. Run concurrent studies, stay organized and detail‑oriented to meet study timelines. Participate in weekend/evening dosing rotations as needed. Support in vitro assays as required. Communicate results to immediate team and follow established protocols and safety procedures. Work in a flexible team‑oriented environment; weekend and evening work may be required. What We Expect Of You We seek a driven, proactive, independent, and enthusiastic scientist who wants to contribute to cutting‑edge science and serve patients in a highly productive team environment. Basic Qualifications Master's degree and 1 year of immunology or related experience. OR Bachelors degree and 3 years of immunology or related experience. Preferred Qualifications M.S. degree in immunology or related disciplines, or B.S. degree with commensurate scientific–drug discovery experience and track record of scientific excellence and productivity. Strong understanding of immunology and inflammation biology and principles. Willingness and curiosity to learn and explore new areas of research. Significant experience designing and executing concurrent in vivo preclinical inflammation and autoimmune disease models. Experience with colitis (DSS, CD45RBhi T cell transfer, IL‑10 KO), lupus (NZB/W, MRL‑lpr, Imiquimod), and arthritis (CIA, CAIA), GvHD models preferred. Experience in asthma, COPD, HS, PBC a plus. Hands‑on experience with in vivo techniques including dosing route of administration (i.v., i.p., p.o., i.n., i.t., r.o., i.d., s.c.), bleeds (r.o., cheek, tail), necropsy (organ collection intestine/colon, lung, lymphnodes, spleen, liver, kidney, skin), cardiac bleed, lung BAL collection. Hands‑on experience in cellular, biochemical, histological, and molecular biology assay techniques (ELISA, MSD, quantitative RT‑PCR, BCA protein measurements) preferred. Hands‑on experience with multicolor flow cytometry including spectral flow approaches and immune cell populations is essential. Computer literacy, especially proficiency with GraphPad Prism, Excel, PowerPoint and Word. Attention to detail, excellent organizational and communication skills, accurate & timely record keeping and data analysis are essential. Demonstrated track record of independent critical thinking and scientific achievement. Demonstrated experience in pharmacology and in vivo models of inflammation/immunology. What You Can Expect Of Us From our competitive benefits to our collaborative culture, we support your professional and personal growth. Benefits A comprehensive employee benefits package including retirement and savings plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan. Stock‑based long‑term incentives. Award‑winning time‑off plans. Flexible work models where possible. Equal Opportunity Employer Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. #J-18808-Ljbffr BioSpace