Principal Scientist, Computational-Immunology Discovery

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Job Function: Data Analytics & Computational Sciences Job Sub Function: Bioinformatics Job Category: Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America, La Jolla, California, United States of America, Spring House, Pennsylvania, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at About Immunology Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. We are searching for the best talent for a Principal Scientist, Computational-Immunology Discovery, to be in Spring House, PA, La Jolla, CA or Cambridge, MA. This role is on the Immune Pathway Discovery (IPD) team which is part of Immunology Discovery in the Immunology Therapeutic Area. IPD is responsible for identifying the next wave of transformational therapeutic pathways and applying human ‘omics data to advance our Discovery portfolio. We analyze and interpret high-dimensional molecular ‘omics data to identify new therapeutic pathways, build disease rationales, and identify patient stratification approaches. IPD supports Discovery projects from inception, through preclinical testing, and up to the transition to clinical trials. We partner closely with biologists to formulate questions, interpret results, and apply the insights we generate to influence the strategic direction of the program. This is an individual contributor role focused on supporting key projects and initiatives with computational analysis. The successful candidate will have a strong technical background in bioinformatics and established track record of using bioinformatics to drive business impact. Due to the interdisciplinary nature of this role, strong technical, collaboration, communication, and time management skills are critical. Key Responsibilities: Independently build, align, and execute technical plans to achieve objectives across multiple programs. Timely delivery of hands-on data analysis, visualization, and interpretation for Discovery portfolio decision-making. Substantially impact Discovery programs through direct technical execution and indirect contribution as a member of Discovery project teams. Collaborate with cross-functional teams to drive computational insights for Discovery programs. Requirements: PhD in a field relevant to bioinformatics including, but not limited to, Computational Biology, Immunology, Biostatistics, or Computer Science. 4+ years work experience using computational biology to discover biological insights from molecular data in immunology or an immunology-related field. Deep technical expertise analyzing ‘omics data, including bulk and single cell RNA-seq. Fluent in R and/or Python. Cloud computing experience is a plus. A proven ability to communicate and collaborate across disciplines. Exceptional scientific rigor and attention to detail. Agentic AI and AI-assisted coding experience in an industry setting, or a strong motivation to learn. Preferred experiences: Background in inflammatory diseases, wet lab experience is a plus. Motivation to shape the technical direction of Immune Pathway Discovery by piloting new approaches and demonstrating their potential impact. Expertise in machine learning, data management, spatial transcriptomics, or network biology. Ability to build and leverage a strong scientific network to drive portfolio impact. The anticipated base pay range for this position is $115,000 to $227,000 Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program. Employees are eligible for the following time off benefits: – Vacation – up to 120 hours per calendar year – Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year – Holiday pay, including Floating Holidays – up to 13 days per calendar year – Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below. For additional general information on company benefits, please go to: - Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via . Internal employees contact AskGS to be directed to your accommodation resource. #LI-Hybrid Required Skills: Preferred Skills: Advanced Analytics, Analytical Reasoning, Bioinformatics, Coaching, Critical Thinking, Database Structures, Data Privacy Standards, Data Science, Industry Analysis, Interdisciplinary Work, Organizing, Productivity Planning, Quality Standards, Science, Technology, Engineering, and Math (STEM) Application, Scripting Languages, Statistical Computing, Technical Credibility, Technical Writing The anticipated base pay range for this position is : $117,000.00 - $201,250.00 Additional Description for Pay Transparency: At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at Do Not Sell or Share My Personal Information Limit the Use of My Personal Information