Senior Manager, HTA, Value & Evidence (HV&E)- Breast Cancer

ROLE SUMMARY

As a leading biopharmaceutical company, Pfizer is dedicated to the discovery and delivery of high value therapies across a variety of disease areas. It is our mission to bring innovative medicines to patients that significantly improve their lives, and our priority is to ensure patients have access to these medicines.

The Health Technology Assessment (HTA), Value & Evidence (HV&E) team is responsible for ensuring patients have affordable, timely access to medicines and vaccines by advancing innovative value and evidence solutions to inform healthcare decision-making.

The HV&E Senior Manager is responsible for development and execution of high-quality HV&E strategic efforts to support optimal access and reimbursement for breast cancer medicines. This role directly impacts business objectives on a global basis by providing strategic guidance and robust evidence development relevant to achieve optimal global patient access by demonstrating the value of Pfizer’s breast cancer medicines.

This position will be part of Pfizer’s dynamic HV&E team, part of Pfizer’s US Medical Affairs department and will have an important role of managing health economics and outcomes research (HEOR) to generate data to support patient access to breast cancer with a primary focus on Prifetrastat. This position will be working closely with the broader breast cancer team, various cross-functional teams (e.g., medical, clinical, commercial, etc.), and country colleagues to foster a culture that promotes innovation and thrives on doing better for Pfizer’s patients and society in general. This position will function in a closely aligned fashion with the Global Access Strategy and Pricing (GASP) team to ensure there is a single and coordinated view on strategy and project execution for optimizing access evidence generation.

This position will function with a “One Pfizer” mindset and will be expected to partner with Pfizer colleagues in various regional and national markets to ensure a consistent and robust evidence generation strategy.

ROLE RESPONSIBILITIES

• Support the development of the Global HTA Value & Evidence Strategy in close partnership with the cross-functional Prifetrastat team
• Manage execution of clinically relevant and scientifically valid Value & Evidence studies and projects (including non-interventional studies, registries, etc.) in alignment with the global Value & Evidence Strategy to demonstrate the value proposition catered to diverse stakeholders (regulators, payers, patients, physicians, and policy makers)
• Lead updates of tools including global value dossiers (GVDs), economic models, and innovative tools to support value proposition
• Develop real world evidence generation strategies and execute studies to support brand differentiation and value proposition
• Lead the coordination of input from local country/regional Access & Value teams on evidence needs and ensure that input is appropriately incorporated to support demonstration of product value and optimize patient access
• Lead the development of data dissemination plans and communicate, in a timely manner, evidence generated for various stakeholders via publications and conference presentations

• Provide leadership on projects to ensure timely execution of PRO/PCOA research to characterize patient outcomes, identify patient preferences and unmet needs, inform patient-focused measurement strategies, and develop and validate innovative patient-relevant outcomes measures and endpoints to differentiate Pfizer’s portfolio and meet business and global needs.
• Ensures the scientific quality and integrity of PRO research through development of rigorous qualitative and quantitative study research proposals, protocols, analysis plans and reports

BASIC QUALIFICATIONS

• Graduate degree (e.g., MSc, MPH, PhD, DrPH) in HEOR-relevant field such as health services research, health economics, epidemiology, pharmacy administration/pharmaceutical policy, or other research-focused public health field.
• Minimum 5 years of years of experience with MSc/MPH/MBA degree; ≥ 1 years with PharmD/PhD/DrPH in HEOR or relevant related fields (health economics, epidemiology, health services research, or other research-focused public health field)
• Advanced understanding of HEOR concepts, fundamental health services research methods (e.g., health economics, patient reported outcomes, research study design, database analyses, epidemiology, and statistics), data interpretation and external environmental trends influencing health care/pharmaceuticals in key markets worldwide
• Strong project management skills (contracting, budgeting, vendor management)
• Demonstrated ability to oversee small project teams and leadership exposure
• Demonstrated advanced understanding of project execution, ability to manage multiple projects involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
• Excellent interpersonal skills required; ability to understand and respond to multiple internal and external customers and influence in a matrix environment
• Excellent oral and written English communication skills required
• Skilled in functioning within a matrix organization where managing through influence is required

PREFERRED QUALIFICATIONS

• Experience with clinical trials, patient reported outcomes, and real-world study design and implementation desirable
• Knowledge and experience in breast cancer
• Experience in the biotech/pharmaceutical industry
• Completion of an HEOR-related fellowship

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Ability to travel domestically and internationally
• Ability to work in all US time zones

Other Job Details

• Last Date to Apply: October 22, 2026

The annual base salary for this position ranges from $139,100.00 to $231,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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Market Access