Clinical Trial Supply Manager

Business Introduction At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our RDS focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, focusing our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together. Position Summary You will provide tactical oversight of the end‑to‑end supply chain for assigned GSK RDS clinical studies, from protocol review through to study close‑out and reconciliation. You will define detailed demand and supply plans for investigational drugs or treatments that consistently deliver on time to patients while ensuring that supply chain performance supports published study milestones. You will review and influence clinical protocols relative to investigational product supply and determine optimal, patient‑focused, risk‑adjusted and cost‑effective supply plans. As part of the Study Team Operating model (STOM), you will act as the primary interface between supply chain and the clinical study team, ensuring accurate and timely communication across all partner organisations. This role supports Phase I-IV GSK-sponsored clinical studies, investigator-sponsored trials and compassionate use studies. Responsibilities Lead operational supply set‑up and follow‑up for one or more clinical studies, from protocol input through to study close‑out and reconciliation, ensuring investigational product supply is not on the critical path. Serve as the primary supply chain interface with the clinical study team (Global Study Manager/Lead, Local Delivery Lead, Quality...), following STOM principles and supporting asset-level supply strategy in partnership with the Clinical Manufacturing and Supply Chain (CMSC) Workstream Lead. Review and challenge clinical protocols with respect to IP supply, ensuring supply feasibility, identifying constraints, and agreeing supply options and risks with study teams before study initiation. Develop, implement and maintain IP demand and supply plans for each assigned study, modelling demand from patient enrolment forecasts, treatment regimens, duration and protocol design, and keeping plans up to date as studies progress. Define and manage depot and pack site inventory policies and collaborate with worldwide depots to meet in‑country requirements, including management of IP expiry, extensions, replenishment and destruction strategies. Ensure label content and data are defined in the appropriate systems; liaise with labelling and packaging experts on pack design and components; and ensure appropriate IRT contracts and study set‑up are in place, including packing and distribution strategies and IVRS/IWRS specifications as applicable. Execute supply plans to deliver on published study milestones with consistent, on‑time, compliant delivery to patients while minimising waste and ensuring timely communication and escalation of supply issues. Lead complex problem solving across technical, quality, regulatory and operational dimensions without compromising quality, cost or delivery, maintaining appropriate documentation in accordance with GxP and the Trial Master File (TMF). Monitor study KPIs, identify trends and implement corrective and preventive actions, contributing to continuous improvement of supply chain processes and ways of working. Oversee externalised supply chain activities by creating study‑specific technical agreements, providing inputs to vendor proposals and proactively identifying and resolving obstacles with external partners. Basic Qualification University degree in life sciences, pharmacy, logistics, engineering or related field. Minimum 5 years’ experience in clinical supply management, clinical operations or logistics for clinical trials. Experience with clinical trial study designs and approaches and their implications for investigational product supply chains. Demonstrated knowledge of investigational product supply management, inventory management and supply chain/planning principles. Proven ability to manage multiple and complex projects requiring strong problem-solving and innovative thinking to address global supply challenges. Knowledge of regulatory requirements including GMP, GCP and a solid understanding of the drug development process across phases I-IV. Experience with IRT/IVRS/IWRS systems, particularly for supply management and patient randomisation. Strong organisational and planning skills with excellent written and oral communication, and demonstrated ability to work with aggressive, changing timelines and limited information. Ability to lead and work effectively within cross‑functional teams across functional and geographical boundaries, with operational expertise in risk management and contingency planning and strong analytical and strategic thinking. Fluent English (written and spoken); additional local language skills are an advantage. Preferred Qualification APICS or CILT certification, and/or Lean Sigma training or experience. Project management training or experience (e.g. PMP, PRINCE2) and practical experience managing projects in a matrix or remote environment. Experience in warehouse outsourcing oversight, depot network management and global clinical distribution networks. Experience creating and maintaining study documentation (SOPs, guidance, training materials) and study KPIs to support continuous improvement of supply chain processes. Additional language skills (for example, French) are an asset. Salary and Benefits Italian Salary Range: EUR 48,375 to EUR 80,625 Belgium Salary Range: EUR 69,600 to EUR 116,000 The annual gross base salary range for new hires in this position is listed above for each applicable location. These ranges take into account a number of factors including the candidate’s skills, experience, education level and the market rate for the role. In addition, this position may offer an annual bonus and eligibility to participate in our share‑based long‑term incentive programme which is dependent on the level of the role. More detailed information on the total benefits package will be supplied during the recruitment process. Salary ranges for other locations are shown because some markets have pay transparency laws that require salary information on job postings, and those locations are potential job sites for this role. Offers are typically made within the advertised range based on the candidate’s skills, experience and qualifications, with the upper end generally reserved for highly experienced candidates or other exceptional circumstances aligned with these criteria. Accessibility Statement If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements. #J-18808-Ljbffr GlaxoSmithKline