Director, Portfolio Governance

Director, Portfolio Governance

The Director, Portfolio Governance is a strategic leadership role accountable for designing, enabling, and continuously improving the Development governance framework that drives high-quality, timely decision-making across the development portfolio. This role embeds decision excellence, clarity of decision rights, and disciplined execution across the governance forums. This leader ensures decisions are made at the right level, with the right information, at the right time—enabling portfolio tradeoff decisions, reducing cycle time, and improving decision quality and durability.

This role is a hands-on contributor and people manager responsible to build relationships at all levels of the organization in order to solicit and action stakeholder input regarding the governance framework. This role will navigate the fast-paced and agile environment of Regeneron in a collaborative and innovative manner.

***Please note this role is an onsite opportunity and is not eligible remote.

A typical day in this role looks like:

• Own and continuously evolve the governance framework to enable effective, scalable decision-making across the portfolio.
• Establish and enforce decision quality and readiness standards, including clear articulation of options, trade-offs, risks, and recommendations.
• Where required, facilitate governance forums to ensure structured, decision-focused discussions and clear, actionable outcomes.
• Define and manage governance performance metrics (e.g., decision cycle time, right-first-time decisions, deferrals, forum utilization) to assess effectiveness.
• Translate governance metrics and feedback into actionable insights, driving a closed-loop continuous improvement model.
• Synthesize governance outputs into portfolio-level insights, identifying cross-program risks, recurring issues, and systemic bottlenecks.
• Establish and maintain centralized decision documentation and knowledge management practices to ensure transparency and traceability.
• Oversee governance intake, prioritization, and scheduling to ensure alignment to strategic importance, while advancing efficient, scalable processes and leveraging technology to streamline execution.
• Drive cross-forum integration to streamline escalation pathways, eliminate duplication, and improve decision flow.
• Partner closely with senior leaders, governance chairs, and stakeholders to align priorities and reinforce governance expectations.
• Implement governance quality and experience measurement, incorporating multi-directional feedback from teams, executives, and chairs to improve effectiveness.
• Coach and develop team members ensuring that the organizational strategy delivers the skills, capabilities and processes that enable portfolio delivery are present in his/her team

This role may be for you if you have:

• Deep understanding of drug development lifecycle and portfolio management.
• Proven experience designing governance frameworks, operating models, or decision-making processes.
• Strong analytical skills with ability to translate data into insights and actions.
• Experience with process improvement methodologies (Lean, Six Sigma) preferred.
• Exceptional executive communication and facilitation skills.
• Demonstrated ability to influence senior leadership and drive change in matrixed environments.
• Strong stakeholder management and cross-functional leadership capabilities.
• Demonstrate experience leading and developing high-performance teams, including direct people management.
• Experience leveraging technology and digital solutions to enable scalable processes, improve efficiency and enhance decision-making (e.g. dashboards, workflow tools, analytics platforms).
• Ability to travel (<10%).

In order to be considered qualified for the this role a minimum of a Bachelor's degree and Minimum 12+ years of experience in biotechnology, pharmaceutical development, or consulting.

Salary Range (annually)

$183,100.00 - $305,200.00