Senior Director, Investor Relations

About Stoke: Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to selectively restore naturally-occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke’s initial focus are diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for Stoke’s proprietary approach. Stoke is headquartered in Bedford, Massachusetts. For more information, visit Position Purpose: The Sr. Director, Investor Relations will be responsible for leading the development and execution of Stoke’s strategic planning and engagement with the investment community to support the company’s goal of ensuring an accurate understanding of the company’s vision, strategy and its fair valuation. As the primary point of contact for all Stoke investor relations, s/he will establish and maintain credibility and trust with the investment community, including current shareholders, prospective shareholders and sell-side financial analysts. This position will report to the Chief of Corporate Affairs and Strategic Partnerships and will work closely with members of the executive team, providing guidance on all investor interactions. Key Responsibilities: Lead investor relations efforts on behalf of Stoke, including the development and implementation of a strategic plan that helps ensure an accurate understanding of the company story (vision, strategy, pipeline, competitive position) and a fair valuation. Cultivate and maintain strong relationships with investors (current and potential future) and sell-side research analysts. Effectively anticipate investor needs by maintaining a current understanding of the industry and competitive landscape as well as a deep understanding of Stoke’s business and progress. Serve as primary point of contact for all investor inquiries, providing timely, consistent, compliant and accurate responses. Monitor and assess market and sector dynamics as well as all investment research (including models and estimates) on Stoke and its industry peers. Provide data and metrics-driven insights into the market and competitive landscape, using the information to counsel senior management and guide investor communications and activities. Provide internal and external audiences with an accurate and timely view of the company’s performance and perception among the investment community. Provide feedback to management and advise the organization on ways to engage and continuously improve. Continuously evaluate Stoke’s performance with investors and use data, including keen observation and critical thinking skills, to guide Stoke’s ongoing investor-focused activities. Work to establish the optimal mix of shareholders for Stoke at each stage of its evolution through strategic and thoughtful targeting initiatives. Partner closely with Finance, Legal and other departments to ensure accurate and appropriate information for financial reporting, including as part of quarterly communications and regular SEC filings. Partner closely with business partners and collaborators on investor-facing content and disclosures. Work collaboratively across the organization to stay current on company progress to guide investor-focused communications. Lead the planning and development of road shows, conferences, shareholder meetings, bus tours and one-on-one meetings. Review, develop and provide input into external communications materials with Wall Street in mind. This includes corporate materials (press releases, presentations, scripts, website content) as well as publications, medical and scientific communications among other content. Manage the Investor Relations section of the company website and assist with social and digital communications. Establish and maintain the company’s Investor Relations calendar to ensure consistent news flow delivered with an appropriate cadence. Manage external agencies and vendors that are supporting investor communications and activities. Required Skills & Experience: Bachelor’s Degree, preferably in Business, Finance, Accounting or a related field. Post-graduate degree a plus. 12+ years of investor relations in a publicly-traded biotech or pharmaceutical company, preferably for a high-growth organization. Ideal candidate has experience in investor relations, corporate communications, corporate strategy, equity research, investment banking and/or finance. Established relationships with industry analysts and institutional investors with a demonstrated ability to successfully manage these relationships. Has a reputation as a trusted IR professional. Excellent communications skills: written, verbal and presentation delivery. Experience in financial writing. Demonstrated ability to effectively influence, with and without authority. Demonstrated ability to simplify complex information and synthesize and distill information into clear, concise and simple messages that help to effectively communicate the company story. Results-driver with proven ability to identify and analyze business dynamics to develop and implement plans to support investor relations activities. Strategic thinker and problem solver; intellectually curious and perceptive; able to identify interdependencies and connections across the business; a critical thinker. Comfortable in a fast-moving, rapidly changing environment; able to establish structure and process when needed; consistently prioritizes high-impact projects; calm under pressure; works with a sense of purpose and urgency. Understanding of laws and regulations governing the industry and publicly-traded company communications and investor engagement activities. Holds self and others to a high standard of ethics and integrity. Maintains confidentiality, exercises good judgment and discretion. Demonstrated ability to lead, influence and collaborate across the organization and at all levels, both internally and externally. Able to work independently with minimal supervision. Location(s): Stoke is located in Bedford, MA, and will be moving to a new location in Waltham, MA by the end of 2026. This position is a hybrid position currently based in Bedford and will later be based in Waltham. Travel: This position will require approximately 20-30% travel. Compensation & Benefits: At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program. The anticipated salary range for this role is $268,000 - $308,000. The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation. Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP). Culture & Values: At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation. Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do. Interested candidates: Please visit Stoke’s website to learn more and apply directly to the position listed on our Career Center: For more information, visit All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E-Verify.