Principal Scientist, Machine Learning (Large Language Models)
Flagship Ventures
The Role FL97 is seeking an experienced, creative, and talented Principal Scientist, ML (LLMs) to join our team. You will be part of an agile, cross-functional team responsible for training state-of-the-art, large-scale models on the scientific corpora, fine-tuning models with feedback (e.g. RLHF/DPO) and integrating multimodal scientific data. Together with biologists, bioinformaticians, software developers, and automation engineers, you will work on reimagining the way scientific research is conducted. The ideal candidate has a machine learning background, with previous experience building large-scale generative models, complex pre-processing pipelines, and comprehensive benchmarks to support scientific tasks. Mature software engineering skills and familiarity with best practices in software development are also highly desired. Candidates should have experience and/or interest in: Designing, training, and fine-tuning large language models (LLMs), including the ability to successfully adapt an LLM for use in a specific domain. Leveraging NLP tools to solve real world problems that require sequential decision making. Implementing rigorous testing, documentation, and model benchmarking. Qualifications: PhD in computer science, applied mathematics, physics, computational biology or other quantitative disciplines. 5+ years of experience in developing deep learning and/or NLP models. Contributions to research conferences or journals (e.g. NeurIPS, ICML, AAAI, ICLR) Expertise in at least one ML framework (PyTorch/TensorFlow/Jax) and robust experience in the Python data science ecosystem. Experience in training and deploying ML models on distributed computing services (g. AWS/GCP/Azure, or clusters). Bonus: Experience with knowledge graphs, prompting techniques (e.g., Chain-of-Thought), RAG, and/or autonomous agents. Bonus: Incorporating these models into AI-enabled toolchains for the biology lab. Working at FL97, you would have access to advanced technology in the areas of: AI experimental design and simulation Automated liquid handling and instrumentation Generative molecular design More About Flagship Pioneering Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. #J-18808-Ljbffr Flagship Ventures
$168k - $252k
...scientifically rigorous AI co-scientists that enhance compound... ...operational guardrails governing model usage, data access,... ...cheminformatics, molecular design, machine learning, scientific data science,... ...AI technologies, including large language models, agentic systems,...PrincipalLanguageFull timeSummer workRemote workFlexible hours2 days per week3 days per week$216k - $297k
...recent advances in AI, machine learning, and data to... ...Flagship’s integrated model of science, entrepreneurship... ...talented machine learning scientists innovating on model... ...Intelligence and Flagship-at-large to apply our reasoning... ...models, protein language models, genomic foundation...PrincipalLanguage$168k - $252k
...project teams to develop and deploy AI co-scientists supporting design, analysis, and lead... ...computational chemistry, cheminformatics, machine learning, or scientific data science ~ Strong understanding of large language models, agentic systems, and AI-assisted scientific...PrincipalLanguage$146k - $236k
...and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a... ...portfolio of AI-first companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms...Principal$168k - $252k
...is seeking an accomplished Senior Principal Scientist with proven record of developing, testing... ...Python skills and solid machine learning/AI foundations - able to write clean... ...modern AI technologies, including large language models, agentic systems, retrieval-augmented...PrincipalLanguageFull timeSummer workRemote workFlexible hours2 days per week3 days per week$270k - $300k
....We are seeking a Principal AI Researcher to join... ...the foundation models that underpin WHOOP... ...wearable sensors, language, biomarkers,... ...the development of large-scale models spanning... ...and representation learning are worth making,... ...experience in large-scale machine learning and AI...PrincipalLanguageFull timeWork at officeRelocation- This AI Research Scientist will lead the design and build... ...biological foundation models that learn shared representations across Quiver’s large-scale all-optical... ...applications. Develop machine learning models to learn... ...multiple programming languages and computational APIs...LanguageRemote work3 days per week
$167.1k - $226.1k
...assistants to guide learning and reasoning. Our neuro... ....As a Senior Applied Scientist, you will play a... ...3+ years of building machine learning models for business application... ...C++, Python or related language- Experience with... ...etc.- Experience with large scale distributed systems...LanguageFlexible hours$157k - $249k
Job TitleSenior Scientist - Physical AI for Surgical... ...by combining model-based robotics... ...including Vision-Language-Action (VLA) models... ...models, multimodal AI, large language models,... ...with reinforcement learning and learning from... ...evaluating, and deploying machine learning models....LanguageFull timeWork at officeImmediate startWork visaRelocation package3 days per week$159.75k - $255.6k
...seeking highly skilled and innovative Machine Learning Scientists to join our AI team, focusing on AI... ...advancing the state-of-the-art in Large Language Models (LLMs), Multimodal Large Language... ...for Sr. ML Scientist, +10 years for Principal ML Scientist experience in Computer...LanguageWork experience placementWork at officeRemote work- ...available for a Research Scientist specializing in AI and Machine Learning for biologics. This... ...sequence-aware predictive models to prioritize oligonucleotide... ..., fine-tuning protein language models, and developing... ...essential. Familiarity with large-scale computing, cloud...LanguageContract workRemote work
- ...collaboration with data scientists, product managers,... ...responsible for large-scale, cross-... ...large-scale ML and AI models underpinning... ...to create a strong learning environment for the... ...implementing production machine learning systems (... ...or a similar language You keep up with state...PrincipalLanguage
$167.1k - $226.1k
...talented, and inventive Senior Applied Scientist with a strong deep learning background, to build industry-... ...Intelligence (GenAI) technology with Large Language Models (LLMs).Key job responsibilities- Design and implement novel machine learning and deep learning models...LanguageTemporary workFlexible hoursShift workDay shift- Role Principal Scientist in Translational Informatics and Predictive Sciences at BMS, focusing... ..., bioinformatics, and machine learning approaches to large-scale clinical and real-world datasets... ..., proteomics), develop predictive models, generate mechanistic insights, and...Principal
$192k - $265k
...seeking a creative, rigorous, and execution-oriented machine learning scientist to join our Model-Driven Design team. This role will focus on building the... ...intent. By integrating machine learning with large-scale experimentation, this approach aims to reduce the...Work at officeShift work$179k - $236k
...disease through single-cell omics and large-scale patient datasets ? This role... ...world-class computational biologists, machine learning scientists, experimental biologists, chemists, clinicians... ...and advance programs from biological model development through hit identification...PrincipalFull timeShift work$204.5k - $267k
...Principal Data ScientistNew York, NY; Boston, MAAbout... ...a Principal Data Scientist at Formation Bio, you... ...developing sophisticated models for patient selection... ...biology, machine learning, and drug development... ...applicationsExperience with large language models (LLM)Demonstrated...PrincipalLanguageWork at officeLocal areaRelocation3 days per week$188k - $282k
...DescriptionVertex is seeking a Senior Principal AI Engineer to design,... ...platform services for model integration, prompt... ...Software Engineering, Machine Learning, Data Engineering, or... ...reusable services for large-scale enterprise... ...AI systems and large language model integration...PrincipalLanguageFull timeSummer work$192.5k - $302.5k
...hardest of these problems. You'll decide when classical machine learning, statistics, or language models is the right tool, and turn good judgment into... ...You bring breadth across classical machine learning on large, messy tabular data, applied statistics, language processing...PrincipalLanguageRemote workWorldwide- ...that work is happening.Principal Solution Architect -... ..., semantic data modeling, enterprise integration... ...to deploy and govern large-scale, production grade... ...Knowledge of graph query languages, ideally including... ...understanding of AI, machine learning, generative AI,...PrincipalLanguageFull timeShift work
$166.64k - $250k
...Experience in full-stack software engineering, AI engineering, machine learning engineering, or intelligent application development Hands... ...and operating production applications powered by large language models, AI workflows, or agentic systems Experience designing and...PrincipalLanguageFull timeSummer workRemote workFlexible hours2 days per week$114.1k - $211.9k
...biomarker plans encompassing assays, models, samples, analyses, timelines,... ...Ethics. Read our brochure to learn more about our global total... ..., Inventory Management, Machine Learning (ML), Medical Research... ...Biology, Python (Programming Language), ScienceSummaryLocation: Cambridge...PrincipalLanguageFull timeLocal areaFlexible hours$144.8k - $217.2k
...approaches including molecular modeling, cheminformatics, data... ...skills and the ability to guide scientists in drug discovery.This is a... ...and programming expertise in languages such as PythonEducation and... ...Vertex, we embrace continuous learning and encourage employees to...PrincipalLanguageFull timeSummer workRemote workFlexible hours2 days per week3 days per week$192.5k - $302.5k
...hardest of these problems. You'll decide when classical machine learning, statistics, or language models is the right tool, and turn good judgment into... ...You bring breadth across classical machine learning on large, messy tabular data, applied statistics, language processing...PrincipalLanguageRemote workWorldwide$142.5k - $256.5k
...and highly motivated Principal Scientist to support computational... ..., and active-learning cycles. Establish computational... ...teams to convert model outputs into... ...generation, protein language models, molecular docking... ...leading-edge methods in machine learning, predictive...PrincipalLanguagePermanent employmentWork at officeWork from home$108.5k - $201.5k
...SummaryInternal Position Title: Principal Scientist I/IILocation:... ...with animal models and ex vivo assays is... ...holidays and other leaves.To learn more about the culture... ...Inventory Management, Machine Learning (ML), Medical... ..., Python (Programming Language), ScienceSummaryLocation...PrincipalLanguageFull timeRelocation package$177k - $221.3k
...Build production machine learning systems that power risk assessment, engagement... ...Convert advanced models for sequential and multi-modal... ...experience using computer languages such as Python , C++ , Scala... ...Experience building large-scale data processing and orchestration...PrincipalLanguageTemporary workSummer workWork from homeWorldwideFlexible hours$181k - $300k
...OpportunityChewy is looking for a Principal Software Engineer to... ..., optimization, machine learning, and AI-assisted... ...learning and optimization models, robotics, and... ...incrementally modernizing large-scale, business-critical... ...programming ability in modern languages, with Java/Kotlin...PrincipalLanguageLocal areaFlexible hours$119.7k - $222.3k
...disciplines, Drug Disposition (ADME, BA), Modeling & Simulation (M&S), and Operations... ...of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided... ...in AI strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered...PrincipalFull time$208k - $286k
...ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental... .... As part of Flagship’s integrated model of science, entrepreneurship, and... ...and beyond. THE ROLE We are seeking a Principal Scientist (Embedded ML/Computational) to lead AI...Principal
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