Sr Engineer - Process Development

Position Summary We are looking for driven, talented Process Engineers to join the Manufacturing Technology & Transfer team within Global Operations. This position is an integral part of our Reagent Development team and is tasked with developing and deploying oligonucleotide manufacturing processes. The individual will partner closely with development teams, Quality, Production, Supply Chain, and other engineering groups to develop and transfer sustainable manufacturing processes. Responsibilities Execute feasibility and development oligonucleotide builds as necessary to support various project timelines. Ideate and create manufacturing processes and define technical requirements for new production equipment. Author procedures and instructions for new manufacturing processes and train production operators to manufacture product in a GMP environment. Troubleshoot new product and manufacturing process issues related to yield, quality and throughput. Construct and execute controlled experiments including DOE’s to optimize processes and scale; address yield/quality issues and drive implementation of solutions into a production environment to meet project goals. Analyze process test results, author reports and inform technical recommendations to improve product and process quality. Work cross functionally with Product Development, Supply Chain, Manufacturing, Quality, EHS and Facilities teams by representing Oligo MTT on NPI core teams. Ensure successful transfer of knowledge into manufacturing and the sustaining support teams. Qualifications Expertise with all oligonucleotide processes (synthesis, cleavage/deprotection, purification, desalting, and in-process and final QC) and equipment (synthesizers, preparative HPLCs, analytical HPLCs, MSs, UVSpecs, etc.). Experience with liquid handlers and ERP systems is a plus. Demonstrated ability to accomplish goals while working across departments. Effective communication (both verbal and written) and organizational skills to manage competing project priorities. Expertise with Statistics, Statistical Process Control and DOE techniques. Experience with cGMP and 21 CFR Part11 and supporting manufacturing in an FDA regulated environment is preferred. Experience with high‑volume production in a high‑tech consumables industry is a plus. Experience with product development processes and project management is a plus. Education / Experience Typically requires a minimum of 5 years of related oligonucleotide experience with a Bachelor’s degree; or 3+ years and a Master’s degree; or a PhD without experience in Chemistry, Biochemistry, Chemical Engineering or equivalent. The estimated base salary range for this Senior Engineer - Process Development role based in the United States is $98,400–$147,600. The actual base pay may be updated during the hiring process. In addition to a base salary, employees are eligible for variable cash programs and equity as part of the compensation package. Benefits Health, dental and vision coverage. Retirement benefits. Paid time off. Access to genomics sequencing and family planning resources. This role is not eligible for visa sponsorship. Illumina is an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. #J-18808-Ljbffr Illumina