Senior Director/Vice President, Program Management (Cambridge)

Senior Director/Vice President, Program Management
Beam Therapeutics, Cambridge, MA, USA
Posted on Jul 17, 2026

Company Overview

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double‑stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values‑driven organization committed to its people, cutting‑edge science, and a vision of providing life‑long cures to patients suffering from serious diseases.

Position Overview

As an experienced Program Manager, you will play a critical role in achieving outcomes for our innovative next‑generation gene editing programs, with a primary focus on leading the Project Management function. In this role, you will manage a team of PMs, who partner closely with the Program Leads to ensure seamless alignment on strategy, execution, and delivery of key milestones. You will harmonize best‑practices in project management and operational execution across the organization, work closely with the Development Review Board (DRB) chair to devise and implement portfolio‑level resource and strategy optimizations, and influence and drive team performance, flexibility, and progress. Your leadership will directly impact Beam’s pipeline and the realization of transformative therapies for patients.

Responsibilities

• Lead the Project Management function by managing a team of PMs and partnering closely with Program Leads.
• Integrate program plans and cross‑functional deliverables (timelines, budgets, resource allocation, risk identification, mitigation plans, scenarios, key documents such as TPPs and IDPs) across the overall portfolio, in line with corporate goals, working closely with the DRB chair.
• Ensure cross‑functional alignment and organizational support for the program plan by facilitating internal and external stakeholder management and communicating program updates at internal forums.
• Provide strategic input into program objectives and ensure alignment with corporate goals.
• Drive scenario planning and trade‑off discussions to enable informed decision‑making at governance forums.
• Establish proactive risk management frameworks and ensure timely escalation of critical issues.
• Develop contingency plans for high‑impact risks and communicate mitigation strategies to leadership.
• Support identification of areas for improvement and provide feedback on potential strategies to achieve successful outcomes.
• Develop agendas, dashboards, and other content to support governance and key leadership forums.
• Partner with functions on portfolio activities such as long‑range planning and budgeting.
• Lead operational excellence initiatives and drive adoption of best practices across the organization.
• Leverage new technologies and AI to drive consistency, improve efficiency, and accelerate execution across the Program Management group.

Qualifications

• 15+ years of experience in the life sciences industry, with at least 5 years of demonstrated program management experience leading cross‑functional teams in biotechnology.
• BS required; preference for an advanced degree (MS, PhD, MBA, etc.).
• Strong preference for experience driving cell and/or gene therapy programs.
• Must live locally and be able to visit Cambridge, MA 1–3 days per week.
• Proven ability to manage competing priorities, influence diverse teams, identify barriers, and manage budgets, timelines, and meeting plans.
• Demonstrated strategic leadership skills, including influencing senior stakeholders and driving decision‑making in complex, matrixed environments.
• Experience managing multiple programs or contributing to portfolio strategy and governance.
• Expertise in risk management, scenario planning, and contingency development.
• Thorough understanding of the R&D phases within a fast‑moving biopharmaceutical organization, including regulatory requirements and clinical development processes for advanced therapies; experience taking programs to commercial launch is strongly preferred.
• Strong leadership and team‑building skills, with experience in conflict resolution and real‑time problem solving.
• Exceptional written and verbal communication skills and proficiency with project‑management tools.
• Comfort with leveraging new technologies and AI‑driven tools to improve program‑management efficiency and consistency.
• Ability to thrive in a fast‑paced, innovative environment and adapt to evolving priorities.

Salary Range

Base salary range: $260,000 – $400,000 USD.