Senior Clinical Scientist

Company Overview Crinetics is a pharmaceutical company based in San Diego, California, focused on developing therapies for endocrine diseases and endocrine‑related tumors. Position Summary The Senior Clinical Scientist works within a multidisciplinary Clinical Development Program to monitor, track, and analyze clinical trial subjects’ data across Phase1‑3 studies, collaborating closely with the Medical Lead and across cross‑functional teams (Pharmacokinetics, Clinical Operations, Biometrics, Pharmacovigilance, Medical Affairs). Key Responsibilities Monitor, track, and analyze clinical trial subjects’ data under supervision of the Clinical Medical Lead, collaborating with investigators, CRO monitors, and the Biometrics team. Regularly review safety and efficacy data, laboratory parameters, patient profiles, listings, summary tables, and coded terms for events of interest. Collaborate with clinical leads and medical directors to align scientific content and program strategy. Support authoring and review of clinical documents such as protocols, amendments, clinical study reports, IBs, ICFs, training documents, charters, manuals, newsletters, monitoring plans, SAPs, DMPs, eCRFs, and regulatory submissions. Address scientific and protocol‑related questions from investigators with the Medical Lead. Contribute to safety narratives, manuscripts, scientific presentations, and regulatory submissions. Support preparation for safety review committees, DSMB/DMC meetings, and database lock activities. Review protocol deviations, propose causes and resolutions, and participate in internal data‑management meetings. Collaborate with Medical Affairs and Patient Advocacy to maintain relationships with investigators, opinion leaders, and patient advocates. Participate in research site identification and relationship building with CROs. Required Education & Experience MD, PhD, PharmD, MPH, MSN, or RN with 8‑10years of industry experience, including 3‑5years in clinical development within a biopharmaceutical company. Knowledge of FDA/EMA regulations, Good Clinical Practice, ICH guidelines, and clinical drug development. Practical experience in daily medical monitoring of clinical trials (safety parameter review, etc.). Strong analytical skills, collaborative team play, interpersonal communication, and leadership influence. Additional Requirements Software proficiency: Windows, MS Office (Outlook, Word, Excel, PowerPoint). Travel: up to 5% of the time. Physical demands: primarily desk work with occasional walking and lifting up to 25lbs. Salary Range $180,000 – $210,000, plus discretionary annual target bonus, stock options, ESPP, and 401(k) match. Equal Opportunity Employer Crinetics is a proud equal‑opportunity employer. We provide equal employment opportunities to all applicants without regard to unlawful considerations of sex, sexual orientation, gender identity, pregnancy, race, color, creed, national or ethnic origin, citizenship, religion, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute protected by applicable local, state or federal laws. #J-18808-Ljbffr Crinetics Pharmaceuticals, Inc.