Senior Advisor, Circular RNA Drug Substance Process
BioSpace
Orna Therapeutics, Inc., a Lilly subsidiary based in Watertown, MA, seeks a Senior Advisor to lead downstream process development and scale-up for circular RNA drug substances. The role emphasizes design of experiments, process optimization, and cross-functional transfer to clinical material. The candidate will collaborate with supply chain, quality, and regulatory teams, and contribute to regulatory documentation while driving rapid project progression in a fast-paced biotech environment. #J-18808-Ljbffr BioSpace
$141k - $228.8k
...cannot address. With our pioneering circular RNA technology, developed at MIT, we are... ...Summary We are seeking an exceptional Senior Advisor to join our team. The candidate will... ...development and scale‑up of drug substance processes. The ideal candidate will have a strong...Senior$141k - $228.8k
Eli Lilly and Company in Watertown, MA, is seeking a Senior Advisor to lead process development for circular RNA manufacturing. The role requires a strong background in downstream process development, with responsibilities including designing experiments and collaboration...Senior- Initial Therapeutics, Inc. is looking for a Senior Advisor to lead process development for circular RNA manufacturing, affecting pre-clinical and clinical studies. The ideal candidate should possess strong skills in problem-solving, collaboration, and communication, along...Senior
- Amgen Inc. is currently seeking a talented Process Development Senior Scientist to join our Drug Substance Technologies group in Cambridge, MA. The successful candidate will leverage their background in organic chemistry and/or biochemistry to invent synthetic routes and...SeniorRemote jobFlexible hours
- What you will do Amgen is currently seeking a talented Process Development Senior Scientist to join our Drug Substance Technologies - Synthetics (DSTS) group at Cambridge, MA. Amgen’s DSTS group within Process Development (PD) is responsible for the invention and development...SeniorContract workRemote workFlexible hours
$141k - $228.8k
...address. With our pioneering circular RNA technology, developed at... ...are seeking an exceptional Senior Advisor, Manufacturing Science and... ...development lifecycle. Support drug substance (DS) and drug product (DP)... ...as part of the application process and any other...SeniorFull timeWork at officeFlexible hours- Relay Therapeutics in Cambridge, MA is seeking a seasoned process chemist to lead drug substance development, scale-up, and external manufacturing collaborations across programs from late research through clinical trials. You will manage tech transfer to global CRO/CDMOs...Senior
- Orna Therapeutics, Inc., a subsidiary of Eli Lilly, is seeking a Senior Advisor to oversee external manufacturing for lipid materials and platform support for circular RNA and LNP therapies, based in Watertown, MA. The role requires extensive CDMO coordination, tech transfers...Senior
- Amgen is seeking a Process Development Senior Scientist to lead development, characterization, scale-up, and support of drug substance processes for late-stage programs. You will work with cell culture and purification experts to advance a diverse pipeline, contributing...Senior
$122k - $174k
The Opportunity:Are you a seasoned process chemist who enjoys working on drug substance projects? Do you love working closely with pharmaceutical development teams and external collaborators to seamlessly transition process development and help drug substance scale up...SeniorContract work$141k - $206.8k
...candidate will design, execute, and oversee experiments for the technical development and scale-up of lipid nanoparticle (LNP) drug product processes. This role offers a unique opportunity to independently drive LNP platform science within Orna, identify knowledge gaps,...Full timeFlexible hours$173k - $285.33k
...and developing novel small molecule drugs for indications in virology and immunology... ...What You'll Do As a Director/Senior Director, CMC Drug Substance Development, you will be an integral... ...design, execute, and lead chemical process development and manufacturing...Senior$150k - $211k
...for an Associate Director in Boston to oversee biopharmaceutical processes. This pivotal role commands responsibility for technical oversight, lifecycle management, and regulatory support for drug substances. The ideal candidate will have a Ph.D. and extensive experience...SeniorRemote job- ...external studies. You will partner with multiple functions to align priorities, monitor KPIs, and drive continuous improvement in early drug discovery programs. This role emphasizes data-driven decision making, concise communication, and proactive problem-solving to...Senior
$220k - $240k
...and safe manufacture of new drug therapies. When you join... ...professional to serve as a Senior Principal Scientific Advisor within our Safety Assessment... ...therapies, oligonucleotides, RNA-based therapeutics,... ...participate in the resume submission process, please contact a member of...SeniorContract workLocal areaRemote workWorldwideFlexible hours- Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, seeks a Senior Principal Scientist to drive analytical characterization of circular RNA and LNP-based therapeutics, focusing on LC‑MS/MS methods and cross‑functional collaboration in a fast-paced...Senior
$165k - $200k
...Manager / Associate Director, Late-Phase Drug Substance PD/MSAT At Merida Biosciences, we are... ...closely with our upstream and downstream process development SMEs and Head of Drug Substance... ...this role upfront: typically for the Senior Manager/Associate Director we target $1...SeniorLocal area- ...together with Orna Therapeutics, Inc., a Lilly subsidiary based in Watertown, MA, is seeking a Senior Principal Scientist to drive analytical characterization of circular RNA and lipid nanoparticle‑based therapeutics using LC‑MS/MS. You will partner with Platform Science...Senior
$153k - $211k
...support cross‑site collaboration and business needs. Responsibilities Subject matter expert (SME) for Small Molecules Drug Substance Manufacturing. Process owner of Small Molecules process validation for Sobi products. Lead and execute MSAT projects such as...SeniorContract workTemporary workOverseas- Lilly is seeking a Senior Principal Scientist to drive analytical characterization of circular RNA and lipid nanoparticle-based therapeutics with a focus on mass spectrometry. The candidate will develop and qualify LC-MS/MS assays and lead method transfer to partners in...Senior
$71.25k - $187k
...are seeking an exceptional Senior Principal Scientist to join... ...analytical characterization of circular RNA and lipid nanoparticle-based... .... Develop and optimize drug substance and drug product LC‑MS/MS assays... ...as part of the application process and any other correspondence...SeniorFull timeH1bVisa sponsorshipWork visaFlexible hours$122k - $174k
...:You will be an integral part of Relay’s drug product development team supporting Relay... ...drug product formulations and manufacturing process to enable early-stage clinical studies.... ...compoundsYou will coordinate with drug substance, DMPK, toxicology and analytical, to ensure...Senior- Eli Lilly and Company seeks a Senior Advisor, Manufacturing Science and Technology in Watertown, MA. You'll manage external manufacturing activities for proprietary lipid manufacturing while working closely with suppliers and internal teams. The ideal candidate has a PhD...Senior
- Amgen is hiring a Process Development Senior Scientist to lead development, characterization, scale-up and support of drug substance processes to advance programs from Ph II/III through regulatory submission. You will work in a cross-functional team with bioprocessing,...Senior
- ...The role involves executing production processes, collaborating with Analytical and QC teams... ...statistical analyses to support drug development. The ideal candidate holds a... ...field and has extensive experience in drug substance process development, specifically with mRNA...Senior
$122k - $174k
...You will be an integral part of Relay’s drug product development team supporting Relay... ...product formulation and manufacturing processes that ensure product quality and are commercially... ...supply.You will partner with drug substance and analytical development functions to...SeniorImmediate start- Drug Development Project Manager - Boston ICON plc is a world-leading healthcare intelligence... ...the future of clinical development. The Senior Drug Development Project Manager oversees... ...for project management techniques and processes, coaching team members on consistent...SeniorFlexible hours
- Emergent Biosolutions is seeking a Bioprocess Specialist at its Canton, MA site to support GMP vaccine drug substance manufacturing. This senior role involves hands-on technical leadership, ensuring production quality, compliance, and successful regulatory inspections....Senior
- Senior Research Associate, Process Sciences -- for growing RNA CDMO in Boston Full-time, permanent, fully onsite role No visa... ...generation RNA therapeutics and drug product manufacturing. As a Senior... ...experience in mRNA/xRNA or drug substance process development. Hands-on...SeniorPermanent employmentFull timeWork at officeVisa sponsorshipFree visa
$126.07k - $170.56k
...transform the lives of patients while transforming your career.Process Development Senior ScientistWhat you will doLet’s do this. Let’s change the... ...development, characterization, scale-up and support of drug substance processes to enable commercial advancement of programs...SeniorFull timeFlexible hours
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