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R&D Research Associate Evergreen

$83.42k - $134.8k

Merck

Research Associate II / Sr Research Associate (NGS Applications) Onsite in South San Francisco We are seeking a highly motivated and detail-oriented Research Associate to join our dynamic Next-Generation Sequencing (NGS) product development team. In this hands‑on role, you will support the evaluation, optimization, and advancement of cutting‑edge NGS solutions. You will perform high‑quality laboratory experiments, contribute to critical data generation, and help drive successful internal and external adoption of our products. This position is ideal for someone passionate about molecular biology and eager to grow their expertise in NGS workflows, product development, and applications. Responsibilities Perform a wide range of molecular biology techniques to support NGS workflow optimization (e.g., enzymatic and mechanical library prep, DNA purification, PCR/qPCR, QC using BioAnalyzer/TapeStation). Prepare samples to load sequencing runs and help manage sequencing outputs. Assist in testing and optimizing NGS library preparation kits and sequencing workflows (e.g., Illumina, PacBio, Oxford Nanopore). Execute controlled experiments under the guidance of scientists, ensuring consistency, accuracy, and adherence to experimental plans. Support post‑launch product activities by helping analyze customer samples, participating in troubleshooting experiments, and generating data that informs technical documentation. Contribute to drafting technical summaries, figures, and data packages for internal and external use. Support evaluations of new NGS technologies, methods, or reagents under supervision. Use tools such as Python, R, Jupyter notebooks, and common visualization packages to present data clearly. Maintain detailed electronic lab notebooks and documentation to ensure reproducibility and data integrity. Work closely with R&D scientists, product development, and field teams to support development timelines and deliverables. Participate in routine team meetings, providing updates on progress and observations. Qualifications and Required Skills B.S. or M.S. in Molecular Biology, Biochemistry, Genomics, or related fields. Research Associate II – Requires a BS and 2+ years of professional experience or a Master’s degree and 0‑2 years of work experience Sr Research Associate – Requires a BS and 5+ years of professional experience or a Master’s degree and 3+ years of work experience Experience performing NGS library preparation, target enrichment, sequencing and familiarity with sequencing platforms (Illumina required; experience with PacBio or Oxford Nanopore a plus). Hands‑on experience with DNA/RNA purification, library preparation, quantification (Qubit), PCR/qPCR, and electrophoretic QC (BioAnalyzer/TapeStation), enzymatic assays, and primer design. Basic NGS data analysis knowledge (e.g., FastQ metrics, alignment QC metrics) and familiarity using Python, R, or similar tools for data visualization. Strong attention to detail, excellent organizational skills, and ability to follow SOPs and experimental protocols precisely. Clear communication skills and an ability to work collaboratively in a fast‑paced, cross‑functional R&D environment. Ability to manage multiple tasks/experiments and prioritize effectively. Preferred Skills Experience with NGS applications such as WGS, RNA‑Seq, and Metagenomics. Experience with liquid handling systems and automation tools. Job Compensation San Francisco Bay Area Pay Range: $83,423—$134,800 USD. The base cash compensation for this California‑based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations. Equal Employment Opportunity Statement Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law. #J-18808-Ljbffr Merck & Co.

Vacancy posted 2 days ago
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