In Vivo Research Associate

WHO WE ARE Immunovec is a pioneering biotechnology company developing cell type-specific immunotherapies for autoimmune diseases, cancer, and genetic disorders. Launched from stealth in October 2025 with $40.7 million in funding from ARPA‑H's EMBODY program and additional private seed funding, Immunovec is pushing the boundaries of in vivo cell engineering. Our proprietary platform combines cell-type-specific DNA constructs with targeted non-viral delivery particles. We aim to deliver safer, more potent, and far more accessible therapies at unprecedented scale, speed, and cost. When you join Immunovec, you’re joining a mission-driven team at the forefront of in vivo cell engineering, based in the Los Angeles area. ABOUT THE ROLE We are looking for a hands‑on, detail‑oriented Research Associate (RA) or Senior Research Associate (SRA) to join our preclinical research team. You will assist our in vivo cell engineering programs by performing critical procedures such as injection of therapeutic agents, animal health monitoring, sample collection, imaging, and ex vivo analysis. Title and compensation will be commensurate with education and experience. KEY RESPONSIBILITIES Multi-route dosing: Administer cell therapies and nanoparticles via IV (tail vein), IM, SC, and RO routes. Bleeding and sample collection: Conduct retro‑orbital, submandibular, and tail vein bleeds; collect tissues and organs at study timepoints. Humanized mouse models: Generate and maintain PBMC‑engrafted and CD34 HSPC‑engrafted NSG models; monitor engraftment and immune reconstitution. Animal health monitoring: Perform clinical observation scoring, body weight, tumor measurements, and welfare checks per IACUC SOPs. In Vivo and Ex vivo analysis: Perform live animal IVIS imaging. Process blood and tissues/organs for flow cytometry, cytokine profiling, and immune phenotyping. Downstream analysis: Perform multi‑colored flow cytometry analysis of homogenized tissues. Documentation: Maintain accurate ELN entries, animal records, and IACUC compliance logs; update SOPs as needed. Collaboration: Partner with Immunology, Cell Therapy, and Delivery teams; communicate timelines and results clearly. Vivarium operations: Support animal supply management, colony records, and vivarium upkeep. QUALIFICATIONS AND REQUIREMENTS Education: BSc and at least 4 years of hands‑on in vivo experience. Dosing routes: Proficient in at least three of: IV, IM, SC, and RO in rodents. Health monitoring: Skilled in clinical scoring, body weight tracking, and humane endpoint assessment. Imaging: Experience in both live animal and ex vivo organ IVIS imaging. Bleeding: Competent in at least two bleeding techniques (retro‑orbital, submandibular, or tail vein). Immunology foundation: Working knowledge of immune cell biology and standard assays (flow cytometry, ELISA). Organization: Meticulous record‑keeping with strong attention to detail and scientific rigor. Communication: Effective communicator; collaborative team player in a fast‑paced environment. DESIRABLE SKILLS AND EXPERIENCE Experience with T/NK cell engineering in vivo. Xenograft, CDX, or PDX tumor model experience. Flow cytometry panel design and analysis (FlowJo or equivalent). Knowledge and experience with CD34+ HSC‑engrafted humanized mouse models. Molecular biology skills: qPCR, ELISA, Western blot, or IHC. Biotech startup or CRO background. Data analysis proficiency (GraphPad Prism or equivalent). Experience with Larger animal handling is a plus. COMPENSATION AND BENEFITS Compensation range: $75,000-100,000, commensurate with experience and qualifications. Immunovec is proud to provide a comprehensive benefits package, including: 1. Medical, dental, and vision insurance with competitive company contribution. 2. Life, AD&D, and disability insurance. 4. Equity participation (stock options) commensurate with level and experience. 5. Opportunity to work on science with real‑world impact on patient lives. EQUAL OPPORTUNITY EMPLOYER Immunovec is an equal opportunity employer committed to a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, or any other legally protected characteristic. HOW TO APPLY Submit your resume and a brief cover letter to View email address on click.appcast.io . To ensure your application is routed to the right reviewers, please include "In Vivo RA/SRA" in the subject line. For the cover letter, please use the following format: one paragraph describing your work experience and one paragraph describing your goals in your next position. Applications without a cover letter will not be considered. #J-18808-Ljbffr