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Senior Global Director Medical Affairs (GDMA) - Genitourinary Malignancies

$210.4k - $331.1k

Merck & Co.

Job Description

Role Summary

The Global Senior Director Medical Affairs (GDMA) is a subject matter expert responsible for driving execution of the Global Medical and Scientific Affairs (GMSA) portion for their assigned Therapeutic Areas (TA) as part of the Global Value & Implementation (V&I) Plans. The GDMA brings business savviness to the organization and focuses primarily on the US while supporting the Rest of the World (ROW). The GDMA may also serve as a V&I Lead for their disease/asset area, adding additional organizational responsibilities. The GDMA works as part of a high‑performing, results‑driven team that focuses on executional excellence.

Responsibilities and Primary Activities

  • Drive execution of the annual V&I plan with medical affairs colleagues from key countries and regions, focusing on the US.
  • Serve as the subject matter expert (SME) and connector across assigned therapeutic areas, translating global scientific platforms into actionable Medical Value Narratives (MVNs). Engage with country‑level stakeholders—including medical advisors, payers, and scientific leaders—to ensure strategic alignment and support local data generation, congress planning, and advisory boards.
  • Act as the medical representative within Product Development sub‑teams (Clinical, V&I, Commercial, Publications, and Label), leveraging the GMSA vision to drive strategic planning, outcome delivery, and tactical execution.
  • Collaborate closely with V&I Outcomes Research (VIOR), Policy, Commercial, and Market Access teams to identify and address opportunities and barriers in key countries.
  • Serve as a strategic partner for Big Country Markets (US, China, Japan) without an RDMA role, bridging global strategy with local execution.
  • Consolidate actionable medical insights from countries and regions.
  • Engage a network of international scientific leaders and key stakeholders (therapeutic guideline committees, payers, public groups, government officials, medical societies) about the company’s emerging science.
  • Organize global expert input events (advisory boards, expert input forums) to answer questions about developing and implementing new medicines or vaccines.
  • Collaborate with Global Human Health executive directors to inform the GMSA portion of V&I plans and independently lead execution of these plans.
  • Organize global symposia and educational meetings.
  • Support key countries with local data generation study concepts and protocols when requested.
  • Review investigator‑initiated study proposals from key countries before headquarters submission and serve as a review panel member on TA‑specific MISP’s to support the EDSA review process.
  • Manage programs (patient support, educational or risk management) to support safe utilization of company medicines or vaccines.
  • Champion ways of working, emphasizing innovation, medical modernization, and impacting patient outcomes.
  • Manage assigned budget with strong financial stewardship, ensuring delivery within a 3% variance.

Minimum Qualifications

  • M.D., Ph.D. or Pharm.D. (M.D. preferred) with recognized medical expertise.
  • Minimum of 5 years experience in country/region medical affairs or clinical development.
  • Strong prioritization and decision‑making skills.
  • Ability to effectively collaborate with partners across divisions in a matrix environment.
  • Excellent interpersonal, analytical, and communication (written and oral) skills, plus results‑oriented project management abilities.

Preferred Qualifications

  • At least 3 years regional medical affairs experience (e.g., Regional Director Medical Affairs) in GU cancers with a proven track record of contribution to medical affairs strategies.
  • Customer expertise, especially with scientific leadership and other key stakeholders (payers, public groups, government officials, medical professional organizations) in the assigned therapeutic area.

Equal Employment Opportunity Statement

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under U.S. Equal Opportunity Employment laws, visit EEOC Know Your Rights and EEOC GINA Supplement. We are proud to be a company that embraces the value of bringing together talented, committed people with diverse experiences, perspectives, skills, and backgrounds.

Compensation and Benefits

Salary range: $210,400.00 – $331,100.00. Successful candidates will be eligible for annual bonus and long‑term incentive, if applicable. A comprehensive benefits package includes medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits (including 401(k)), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at

Additional Information

  • Location: US and Puerto Rico residents only; San Francisco and Los Angeles residents only per local Fair Chance Ordinances.
  • Travel required: 25%
  • Hybrid work arrangement.
  • Relocation not offered.
  • VISA sponsorship available.
  • Job posting end date: 06/27/2026.

To apply, submit your application through (or via the Workday Jobs Hub if you are a current employee). The application deadline is stated in the posting.

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Vacancy posted 6 hours ago
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