Senior Clinical Trial Manager

Job Opportunity At Genmab

At Genmab, we are dedicated to building extraordinary futures, together, by developing antibody products and groundbreaking antibody medicines that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals' unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

Key Responsibilities

• Lead the operational planning, setup, and execution of global clinical trials, ensuring delivery on time, and in compliance with regulatory and quality standards.
• Oversee trial documentation and systems, ensuring accuracy, completeness, and continuous inspection readiness.
• Drive site feasibility, selection, and activation strategies in collaboration with CROs and internal stakeholders.
• Manage and oversee CROs and other service providers, ensuring high-quality deliverables, adherence to timelines, and effective collaboration.
• Proactively identify, assess, and mitigate operational risks using risk-based quality management approaches.
• Oversee protocol deviations, issue management, and ensure appropriate escalation and resolution of trial-level challenges.
• Monitor trial performance and data quality, leveraging key metrics to drive decision-making and continuous improvement.
• Act as a key cross-functional leader, fostering strong collaboration across internal teams, vendors, and investigators.

Qualifications

• Bachelor's degree in life sciences or related field (Master's degree preferred).
• 8+ years of experience in clinical trial management within the pharmaceutical or biotechnology industry.
• Solid understanding of ICH/GCP regulations and the clinical drug development lifecycle.
• Proven experience managing global, multi-center trials and working in a complex, matrixed organization.
• Strong project management and service provider oversight skills.
• Excellent communication, collaboration, and interpersonal skills.
• Oncology and/or therapeutic area–specific experience is highly desirable.
• Ability to lead without authority and mentor others in a cross-functional environment.

What We Offer

• A dynamic, collaborative, and science-driven culture.
• Opportunities to grow and lead within a high-performing global organization.
• The chance to contribute to meaningful innovation that impacts patients' lives.

For US based candidates, the proposed salary band for this position is as follows:

$130,720.00---$196,080.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives.

When you join Genmab, you're joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for:

• 401(k) Plan: 100% match on the first 6% of contributions
• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

About You

• You are genuinely passionate about our purpose
• You bring precision and excellence to all that you do
• You believe in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with a broad spectrum of backgrounds
• You take pride in enabling the best work of others on the team
• You can grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so!

Locations

Genmab maximizes the efficiency of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are crafted as open, community-based spaces that work to connect employees while being immersed in our powerful laboratories. Whether you're in one of our office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab's vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific.