Senior Python Backend Engineer

Senior Python Backend Engineer

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Senior Python Backend Engineer based in the United States.

This role offers the opportunity to work on highly impactful, cloud-native backend systems powering data-intensive applications in the healthcare and clinical research domain. You will design and scale Python-based backend services that support complex, mission-critical workflows used in global clinical trial environments. The position blends hands-on engineering with architectural leadership, requiring strong ownership of backend systems from design through production. You will work with modern cloud infrastructure on AWS, building highly available and secure services using Kubernetes, serverless components, and microservices patterns. This is a senior-level role where you will collaborate with cross-functional stakeholders while mentoring engineers and driving technical excellence. You will contribute directly to building reliable, scalable systems that improve how clinical data is processed and used worldwide.

Accountabilities:

In this role, you will lead backend engineering efforts while ensuring scalable, secure, and high-performance system design and delivery.

• Design, develop, and maintain backend services and APIs using Python and modern web frameworks
• Architect and optimize PostgreSQL databases, ensuring performance, scalability, and data integrity
• Build and manage AWS-based infrastructure including EKS, Lambda, API Gateway, S3, and IAM
• Define and enforce backend engineering standards, including API design, security practices, and testing strategies
• Lead cloud-to-cloud integrations and implement secure authentication and authorization mechanisms (e.g., OAuth2)
• Mentor and guide backend engineers through code reviews, best practices, and technical leadership
• Collaborate in agile ceremonies and drive end-to-end delivery of backend features and systems
• Ensure observability, reliability, and security of production systems through monitoring and proactive optimization

Requirements:

This role requires strong backend engineering expertise with deep experience in Python, cloud infrastructure, and scalable system design.

• 6+ years of backend engineering experience, including leadership or tech lead responsibilities
• Strong proficiency in Python, REST APIs, SQL, and modern backend frameworks (Pyramid preferred)
• Deep experience with PostgreSQL including schema design, performance tuning, and query optimization
• Hands-on experience with AWS services such as EKS, Lambda, API Gateway, RDS, S3, and IAM
• Strong understanding of microservices, serverless architectures, and distributed systems
• Experience with Docker, CI/CD pipelines, and modern DevOps practices
• Solid grasp of software engineering principles (SOLID, OOP, clean architecture) and security best practices (OWASP)
• Strong communication skills and ability to collaborate across global teams
• Exposure to healthcare or clinical data systems (HL7, FHIR, GxP) is a strong plus
• Bachelor's or Master's degree in Computer Science or related field (or equivalent experience)

Benefits:

• Competitive hourly compensation ($85–$95/hour)
• Comprehensive health coverage including medical, dental, and vision insurance
• Employer-paid disability, life, and AD&D insurance
• Unlimited PTO and generous paid holidays
• Paid parental leave to support work-life balance
• 401(k) retirement savings plan
• Flexible remote-first work environment
• Opportunity to work on impactful, global healthcare technology solutions
• Strong focus on engineering growth, mentorship, and career development.