Senior IT Infrastructure Engineer

Overview SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. Role We are seeking a highly skilled Senior IT Infrastructure Engineer to join our growing organization. While we are not a startup, we are in an active growth phase, and this role requires someone who thrives in a dynamic, evolving environment. This is a hands-on, high-impact position where you will work closely with IT leadership to manage and scale a complex hybrid infrastructure spanning on-premises data centers and cloud environments. You will play a critical role in maintaining stability while also driving improvements, standardization, and growth. We are looking for a self-driven, solution-oriented engineer who is comfortable wearing multiple hats, taking ownership of large initiatives, and operating at a senior technical level. This role requires full-time onsite presence in our Redmond, WA office, with a planned relocation to our new Bothell, WA facility in fall 2026. Key Responsibilities Manage and support a hybrid infrastructure (on-prem + cloud) Administer Palo Alto firewalls, Cisco switches and routers, VMware and Hyper-V environments Design and troubleshoot network configurations including site-to-site VPNs and routing Oversee Microsoft 365 administration including licensing and user management Manage remote tools such as Datto RMM, TeamViewer, GoToAssist Support conference room systems (Logitech) Administer NAS/storage systems for hypervisors Work across Windows Server and Linux (Ubuntu, CentOS, Debian) Assist with SQL systems (preferred) Support Azure/cloud infrastructure (plus) Create documentation, SOPs, and diagrams Support users across multiple locations Qualifications Bachelor's degree in Information Technology, Information Management Systems, Computer Science, or a related field required. Minimum of 5–8 years of hands-on IT infrastructure experience, including server administration, enterprise networking, and end-user support; prior experience in a senior or lead capacity is strongly preferred. Preferred Experience Life Sciences environment experience Waters Empower, UNIFI, Connect Geneious Prime, Dotmatics Discovery Studio, Tableau Regulated environments (GxP, HIPAA) What We’re Looking For Strong network engineering expertise Independent troubleshooting ability Comfort in a fast-paced environment Proactive, go-getter mindset Ability to leverage AI/tools for research Strong documentation and communication skills Ownership and accountability Work Environment Primarily on-site with local travel. Supports distributed teams across the U.S. High-autonomy, collaborative environment. Compensation and Benefits The expected base salary range for this position is $100,000 - $135,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills. SystImmune is a leading and well-funded biotech company with a bright future. We offer a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of 5 years, 15 PTO days per year, sick leave, 11 paid holidays, and more. Equal Opportunity SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. #J-18808-Ljbffr SystImmune Inc.