Principal Scientist in particulate materials characterization & digital sciences

Pfizer seeks a Principal Scientist to advance manufacturing science of solid oral dosage forms by developing innovative characterization methodologies and digital approaches for particulate materials. The role combines experimental expertise with AI and machine learning to generate mechanistic insights that accelerate pharmaceutical development and inform predictive tools.

Responsibilities

• Lead development of innovative characterization methods for drug substances and materials across particulate to bulk scales
• Apply AI and machine learning to analyze particulate materials and extract insights from complex datasets
• Develop and implement automated, high-throughput characterization workflows integrated with digital laboratory environments
• Partner with process modelers and data scientists to establish experimental pipelines supporting model-informed drug product development
• Communicate scientific findings through technical reports, presentations, publications, and patents

Requirements

• PhD with 3+ years relevant experience OR MS with 9+ years in pharmaceutical sciences, chemical engineering, materials science, or related field
• Demonstrated expertise characterizing powders, particulate materials, granular systems, or complex materials
• Strong quantitative and analytical skills with experience managing complex experimental datasets
• Record of scientific publications, presentations, patents, or technology development
• Excellent written and verbal communication and interpersonal skills
• Experience with AI, machine learning, or advanced data-science tools (preferred)
• Familiarity with laboratory automation, robotics, or high-throughput experimentation (preferred)

Compensation: $106,000–$176,600 annual base salary